Presented is a case of Klippel-Trénaunay-Weber (KTW) syndrome. This rare syndrome is associated with a triad of anomalies including varicose veins, cutaneous hemangiomas, and bony or soft tissue hypertrophy. The prominent sonographic finding is multiple cystic areas or localized edema most often located on the lower torso of the fetus. Findings suggestive of KTW syndrome were noted following an 18-week gestation fetal survey and were later confirmed at autopsy.
Warhit J, Goldman M, Sachs L, Weiss L, Pek H: Klippel-Trenaunay-Weber syndrome-appearance in utero. J Clin Ultrasound Med1983;2:515–518.
2.
Yankowitz J, Slagel D, Williamson R: Prenatal diagnosis of Klippel-Trenaunay-Weber syndrome by ultrasound. Prenat Diagn1994;14:745–749.
3.
Benacerraf B: Ultrasound Evaluation of Fetal Syndromes. Philadelphia, PA, Churchill Livingstone, 1998, p 277-227.
4.
Hatjis C, Philip A, Anderson G, Mann L: The in utero ultrasonographic appearance of Klippel-Trenaunay-Weber syndrome. Am J Obstet Gynecol1981;139:972–974.
5.
Sanders R: Structural Fetal Abnormalities—The Total Picture. St Louis, MO, CV Mosby, 1996, pp 17–19, 39–40.
6.
Yancy M, Lasley D, Richards D: An unusual neck mass in a fetus with Klippel-Trenaunay-Weber syndrome. J Ultrasound Med1993;12:779–782.
7.
Klippel M, Trénaunay P: Du naevus variqueux osteohypertophiique. Arch Gen Med1900;185:641–652.
8.
Parkes-Weber F: Angioma formation in connection with hypertrophy of limbs and hemi-hypertrophy. Br J Dermatol1907;19:231-231.
9.
Meholic A, Freimanis A, Stueka J, Lo Piccolo M: Sonographic in utero diagnosis of Klippel-Trenaunay-Weber syndrome. J Ultrasound Med1991;10:111–114.
10.
Drose J, Thickman D, Wiggins J, Haverkamp A: Fetal echocardiographic findings in the Klippel-Trenaunay-Weber syndrome. J Ultrasound Med1991;10:525–527.
11.
Meizner I, Rosenak D, Nadjari M, Maor E: Sonographic diagnosis of Klippel-Trenaunay-Weber syndrome presenting a sacrococcygeal mass at 14-15 weeks gestation. J Ultrasound Med1994;13:901–904.
12.
Shalev E, Romano S, Nseir T, Zuckerman H: Klippel-Trenaunay syndrome—ultrasonic prenatal diagnosis. J Clin Ultrasound1988;16:268–270.
