We propose that stakeholders should develop an economically sustainable, public health intervention to improve indoor air quality and to reduce overcrowding in households of underserved U.S. rural, urban and suburban residents exposed to life-threatening respiratory infections, such as caused by coronavirus disease 2019, influenza, and respiratory syncytial virus. We posit that a multifaceted community-based intervention in these households would improve social inequities, promote health justice, and reduce health care expenditure. However, this call for action would require an interdisciplinary, coordinated, and sustainable action plan devised by federal, state, county, and city government departments and agencies in close collaboration with and input from local community leaders, members, and residents.
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