Abstract
Background
Van Wyk–Grumbach (VWG) syndrome is a rare complication of juvenile hypothyroidism characterized by precocious puberty, delayed bone age, and ovarian cysts.
Case presentation
We report the case of an 8-year-old girl who presented with intermittent vaginal bleeding and abdominal pain. Imaging revealed bilateral multiseptate ovarian cystic lesions. She had been advised to undergo surgical management at a community health center and was subsequently referred to our institution. Following comprehensive clinical, radiological, and biochemical evaluation, a diagnosis of VWG syndrome was established.
Conclusion
VWG syndrome should be considered in pediatric females with bilateral ovarian enlargement and precocious puberty, particularly in the context of delayed bone age and hypothyroidism. Prompt thyroid hormone replacement can prevent unnecessary surgical procedures.
Get full access to this article
View all access options for this article.