Erythema nodosum (EN), a form of septal panniculitis, is rare in pediatric age group. It can be primary/idiopathic as well as secondary due to various conditions such as tuberculosis, streptococcal infections, autoimmune disorders, drugs, and inflammatory bowel diseases. The association of EN with latent tuberculosis has been widely reported in the adult population but literature is scarce on the association of EN with tuberculosis in the pediatric age group.
Here we present a case of a child who presented with pleural effusion of tubercular origin with a recent history of EN. The patient was also evaluated for the other causes of EN and responded well to the antitubercular treatment.
TrapaniS, RubinoC, LodiL, RestiM, & IndolfiG.Erythema nodosum in children: a narrative review and a practical approach. Children (Basel). 2022;9(4):511. Published 2022 Apr 4. doi:10.3390/children904051.
2.
ChenS, ChenJ, ChenL, . Mycobacterium tuberculosis infection is associated with the development of erythema nodosum and nodular vasculitis. PLoS ONE. 2013;8(5):e62653. doi: 10.1371/journal.pone.0062653
Pérez-GarzaDM, Chavez-AlvarezS, Ocampo-CandianiJ, & Gomez-FloresM.Erythema nodosum: a practical approach and diagnostic algorithm. Am J Clin Dermatol. 2021;22(3):367–378.
5.
Bjorn-MortensenK, LadefogedK, SimonsenJ, . Erythema nodosum and the risk of tuberculosis in a high incidence setting. Int J Circumpolar Health. 2016;75(1):32666.
6.
RodriguesCC, NevesFL, & CardosoPN.Tuberculosis presenting as erythema nodosum in childhood. J Paediatr Child Health. 2022;58(9):1674–1675.
7.
KiazykS, & (TB)BallTB.Tuberculosis: latent tuberculosis infection: an overview. Can Commun Dis Rep. 2017;43(3-4):62.
8.
SuárezI, FüngerSM, KrögerS, RademacherJ, FätkenheuerG, & RybnikerJ.The diagnosis and treatment of tuberculosis. Dtsch Arztebl Int. 2019;116:729–735. doi: 10.3238/arztebl.2019.0729
