Occlusion is an effective therapeutic modality for treating psoriasis either by itself or by enhancing the efficacy of topical agents. However, the affordable material available, namely Saran wrap and other similar plastic sheets, make it unfeasible for widespread use. The hydrogel patch is a new medical device that is not only efficacious, but also improves upon the shortcomings of previous occlusive dressing materials. It is not yet available in the market but is expected to become available soon. This article introduces the use of the hydrogel patch and presents patient input regarding its feasibility and acceptability from a bilaterally controlled study for the treatment of psoriasis.
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References
1.
ShoreR.N.Treatment of psoriasis with prolonged application of tape. J Am Acad Dermatol.1986; 15: 540–2.
2.
A trial of the Actiderm dermatological patch, and topical corticosteroids in the treatment of psoriasis vulgaris. The Actiderm Multi-Center Study Group. Cutis.1990; 46: 84–8.
3.
FriedmanS.J.Management of psoriasis vulgaris with a hydrocolloid occlusive dressing. Arch Dermatol.1987; 123: 1046–52.
4.
GottliebA.B., Staiano-CoicoL., CohenS.R.Occlusive hydrocolloid dressings decrease keratinocyte population growth fraction and clinical scale and skin thickness in active psoriatic plaques. J Dermatol Sci.1990; 1: 93–6.
5.
JuhlinL.Treatment of psoriasis and other dermatoses with a single application of a corticosteroid left under a hydrocolloid occlusive dressing for one week. Acta Derm Venereol.1989; 69: 355–7.
6.
VoldenG.Successful treatment of chronic skin diseases with clobetasol propionate and a hydrocolloid occlusive dressing. Acta Derm Venereol.1992; 72: 69–71.
7.
VoldenG., KragballeK., Van De KerkhofP.C.Remission and relapse of chronic plaque psoriasis treated once a week with clobetasol propionate occluded with a hydrocolloid dressing versus twice daily treatment with clobetasol propionate alone. J Dermatolog Treat.2001; 12: 141–4.
8.
WilkinsonR.D., OhayonM.Therapeutic response to a dermatologic patch and betamethasone valerate 0.1 percent cream in the management of chronic plaques in psoriasis. Cutis.1990; 45: 468–70.
9.
KragballeK., LarsenF.G.A hydrocolloid occlusive dressing plus triamcinolone acetonide cream is superior to clobetasol cream in palmo-plantar pustulosis. Acta Derm Venereol.1991; 71: 540–2.
10.
van Vlijmen-WillemsI.M., ChangA., BoezemanJ.B.The immunohistochemical effect of a hydrocolloid occlusive dressing (DuoDERM E) in psoriasis vulgaris. Dermatology.1993; 187: 257–62.
HwangS.M., AhnS.K., MenonG.K.Basis of occlusive therapy in psoriasis: correcting defects in permeability barrier and calcium gradient. Int J Dermatol.2001; 40: 223–31.
16.
DavidM., LoweN.J.Psoriasis therapy: comparative studies with a hydrocolloid dressing, plastic film occlusion, and triamcinolone acetonide cream. J Am Acad Dermatol.1989; 21: 511–4.
17.
MartinG., MarriottC.The influence of a new hydrocolloid dermatological patch on the blanching response induced by topical corticosteroid formulations. Curr Ther Res.1989; 46: 828–36.
18.
CastelijnsF.A., GerritsenM.J., van ErpP.E.Dermatology.2000; 200: 25–30.
19.
AlyR., ShirleyC., CunicoB.Effect of prolonged occlusion on the microbial flora, pH, carbon dioxide and transepidermal water loss on human skin. J Invest Dermatol.1978; 71: 378–81.
20.
ColacoS., SivanesanP., F MalickP.Occlusion with specially designed occlusive hydrogel patch enhancing the efficacy of topical agents in the treatment of psoriasis. Submitted to J Am Acad Dermatol.2007.
21.
van de KerkhofP.C., ChangA., van der WalleH.B.Weekly treatment of psoriasis with a hydrocolloid dressing in combination with triamcinolone acetonide. A controlled comparative study. Acta Derm Venereol.1994; 74: 143–6.
