Apoptosis: A Strategy for Psoriasis

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References

Abbas

A.K.

, Lichtman

A.H.

, Pober

J.S.

Cellular and Molecular Immunology. Philadelphia, W.B. Saunders Company 2000, pp 130–491

Godar

D.E.

Light and Death: Photons and Apoptosis.

J Invest Dermatol. Symposium Porceedings. Photobiology 1999; 4(1): 17–23.

Pope

R.M.

Apoptosis as a therapeutic tool in rheumatoid arthritis.

Immunology 2002; 2: 527–535.

Nickoloff

B.J.

The immunologic and genetic basis of psoriasis.

Arch Dermatol 1999; 135: 1104–1110.

Gottlieb

AB.

Product development for Psoriasis: Clinical Challenges and Opportunities, in Psoriasis, edited by Roenigk

, and Maibach

, Third Edition, Marcel Dekker, Inc., NY, NY, 1998, 421–433.

Gottlieb

A.B.

Psoriasis: Immunopathology and Immunomodulation, Dermatologic Clinics 19: 649–657, 2001.

Cather

, Menter

Novel Therapies for Psoriasis.

Am J Clin Dermatol 2002; 3(3): 159–173.

Ellis

C.N.

, Krueger

G.G.

Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes.

N Engl J Med 2001; 345: 248–256.

Granstein

R.D.

New treatments for psoriasis.

N Engl J Med 2001; 345: 284–287.

10.

Krutmann

, Morita

Mechanisms of Ultraviolet (UV) B and UVA Phototherapy.

J Invest Dermatol, 1999; 4: 70–72.

11.

Krueger

J.G.

The immunologic basis for the treatment of psoriasis with new biologic agents.

J Am Acad Dermatol 2002; 46: 1–23.

12.

Mrowietz

Advances in systemic therapy for psoriasis.

Clin Exp Dermatol 2001; 26: 362–367.

13.

Singri

, West

D.P.

, Gordon

K.B.

Biologic Therapy for Psoriasis. The new therapeutic frontier.

Arch Dermatol 2002. 138: 657–662.

14.

Kumar

. Robbins Basic Pathology. Philadelphia, Saunders 2003, pp 26–30.

15.

Berlinger

Adaptations and Cell Injury. David Geffen School of Medicine at UCLA, Department of Pathology and Laboratory Medicine 2003, pp 23–27.

16.

Gottlieb

S.L.

, Gilleaudeau

, Johnson

, Estes

, Woodworth

T.G.

, Gottlieb

A.B.

, Krueger

J.G.

: Response of psoriasis to a lymphocyte-selective toxin (DAB₃₈₉ IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nat Med 1: 442–447, 1995

17.

Manggau

, Kim

D.S.

, Ruwisch

. 1alpha25-Dihydroxyvitamin D3 Protects Human Keratincytes from Apoptosis by the formation of sphingosine-1-phosphate. J Invest Dermatol 2001; 117: 1241–1248.

18.

Martin

. A multicenter dose-escalation trial with denileukin diftitox (ONTAK, DAB389IL-2) in patients with severe psoriasis. J Am Acad Dermatol 2001; 45: 871–880.

19.

Murphy

. Clinical Clearing of Psoriasis by 6-Thioguanine Correlates with Cutaneous T-cell Depletion via Apoptosis. Arch Dermatol 1999; 135: 1495–1501.

20.

Atreya

. Turning on T-Cell Death and Turning off Crohn's Disease. Gastroenterology 2000; 119: 1166–1168.

21.

Iyer

, Yamauchi

, Lowe

N.J.

. Etanercept for sever psoriasis and psoriatic arthritis: observations on combination therapy. Br J Dermatol 2002; 146: 118–121.

22.

Perlman

. Differential Expression Pattern of the Antiapoptotic Proteins, Bcl-2 and FLIP, in Experimental Arthritis. Arthritis Rheum 2001; 44: 2899–2908.

23.

Zhang

. Regulation of Tumor Necrosis Factor α-Mediated Apoptosis of Rheumatoid Arthritis Synocial Fibroblasts by the Protein Kinase Akt. Arthritis Rheum 2001; 44: 1555–1567.

24.

Van Deventer

S.J.H.

Transmembrane TNF-α, Induction of Apoptosis, and the Efficacyof TNF-targeting Therapies in Crohn's Disease.

Gastroenterology 2001; 121: 1242–1245.

25.

ten Hove

. Infliximab treatment iduces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002; 50: 206–211.

26.

Wei

. The Sushi Domain of Soluble IL-15 Receptor alpha is Essential for Binding IL-15 and Inhibiting Inflammatory and Allogenic Responses in Vitro and In Vivo. J Immunol 2001; 280–282.

27.

Lugering

Andreas

. Infliximab Induces Apoptosis in Monocytes from Patients with Chronic Active Crohn's Disease by Using a Caspase-Dependent Pathway. Gastroenterology 2001; 121(5): 1145–57.

28.

LaDuca

J.R.

, Gaspari

A.A.

Targeting Tumour Necrosis Factor Alpha: New Drugs Used to Modulate Inflammatory Disease.

Dermatologic Clinics 2001; 19: 1–21.

29.

Scallon

. Binding and Functional Comparisons of Two Types of Tumor Necrosis Factor Antagonists. J Pharmacol Exp Ther 2002; 310: 418–426.

30.

Girolomoni

, Abeni

Anti-Tumor Necrosis Factor-α Therapy in Psoriatic Arthritis and Psoriasis.

Arch Dermatol 2001; 137.

31.

Koreck

. CD3+CD56+NK T cells are significantly decreased in the peripheral blood of patients with psoriasis. Clin Exp Immunol 2002; 127: 176–182.

32.

Greaves

M.W.

The immunopharmacology of skin inflammation: the future is already here!

Br J Dermatol 2000; 143: 47–52.

33.

Kirby

, Griffiths

C.E.M.

Psoriasis: the future.

Br J Dermatol 2001; 144: 37–43.

34.

Miracco

. Cyclin D1, B and A expression and cell turnover in psoriatic skin lesions before and after cyclosporin treatment. Br J Dermatol 2000; 143: 950–956.

35.

Trepicchio

WL.

. Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions. J Clin Invest 1999; 104: 1527–1537.

36.

Nakagawa

. Structure-specific control of differentiation and apoptosis of human promyelocytic leukemia (HL-60) cells by A-ring diastereomers of 2-methyl-1alpha, 25-dihydroxyvitamin D₃ and its 20-epimer. Biochem Pharmacol 2000; 60: 1937–1947.

37.

Kondo

, Hozumi

Comparative inhibitory effects of vitamin D₃ and an analogue on normal and psoriatic epidermis in organ culture.

Arch Dermatol 2000; 292: 550–555.

38.

McCarty

M.F.

Upregulation of lymphocyte apoptosis as a strategy for preventing and treating autoimmune disorders: a role for whole-food vegan diets, fish oil and dopamine agonists.

Med Hypotheses 2000; 57: 258–275.

39.

Rodenburg

R.J.T.

. The Antiinflammatory Drug Sulfasalazine Inhibits Tumor Necrosis Factor a Expression in Macrophages by Inducing Apoptosis. Arthritis Rheum 2000; 43: 1941–1950.

40.

Migita

. Nitric Oxide protects cultured rheumatoid synovial cells from Fas-induced apoptosis by inhibiting caspase-3. Immunology 2001; 103: 362–367.

41.

Chou

C.T.

, Yang

J.S.

, Lee

M.R.

Apoptosis in rheumatoid arthritis - expression of Fas, Fas-L, p53, and Bcl-2 in rheumatoid synovial tissues.

J Pathol 2001; 193: 110–116.