Purpose: To describe a case of a drusenoid pigment epithelial detachment that resolved after retinal detachment (RD) repair using multimodal imaging. Methods: A single case was evaluated. Results: An 83-year-old woman with intermediate age-related macular degeneration had repair of a rhegmatogenous RD with subsequent resolution of macular drusen and improved visual acuity and metamorphopsia. Conclusions: RD repair may be associated with resolution of drusen, leading to improved functional outcomes.
WiecekELashkariKDakinSCBexP. A statistical analysis of metamorphopsia in 7106 Amsler grids. Ophthalmology. 2015;122(2): 431-433.
2.
AbdelsalamADel PrioreLZarbinMA. Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression. Surv Ophthalmol. 1999;44(1):1-29.
3.
CukrasCAgrónEKleinML, et al. Natural history of drusenoid pigment epithelial detachment in age-related macular degeneration: Age-Related Eye Disease Study Report No. 28. Ophthalmology. 2010;117(3):489-499.
4.
ParodiMBVirgiliGEvansJR. Laser treatment of drusen to prevent progression to advanced age-related macular degeneration. Cochrane Database Syst Rev. 2009(3):Cd006537.
5.
SalloFBRechtmanEPetoT, et al. Functional aspects of drusen regression in age-related macular degeneration. Br J Ophthalmol. 2009;93(10):1345.
6.
BresslerNMMunozBMaguireMG, et al. Five-year incidence and disappearance of drusen and retinal pigment epithelial abnormalities. Waterman study. Arch Ophthalmol. 1995;113(3):301-308.
7.
KleinRKleinBETomanySCMeuerSMHuangGH. Ten-year incidence and progression of age-related maculopathy: the Beaver Dam eye study. Ophthalmology. 2002;109(10):1767-1779.
8.
SparrowJMDickinsonAJDukeAMThompsonJRGibsonJMRosenthalAR. Seven year follow-up of age-related maculopathy in an elderly British population. Eye (Lond). 1997;11(Pt 3):315-324.
9.
DithmarSPollithySAchT. Disappearance of central confluent soft drusen following vitrectomy and ILM peeling. Eye (Lond). 2013;27(6):779-781.
10.
HolzFGStaudtS. Disappearance of soft drusen following macular hole surgery. Retina. 2001;21(2):184-186.
11.
LeeJHLeeTLeeSCLeeCS. Disappearance of soft drusen and subsequent development of choroidal neovascularization following macular hole surgery: a case report. BMC Ophthalmol. 2015; 15:43.
12.
LimLTHolickiJWalkerJD. Disappearance of extramacular drusen after chronic retinal detachment. Oman J Ophthalmol. 2012; 5(1):67.
13.
MargolisROberMDFreundKB. Disappearance of drusen after rhegmatogenous retinal detachment. Retin Cases Brief Rep. 2010;4(3):254-256.
14.
HollbornMFranckeMIandievI, et al. Early activation of inflammation- and immune response-related genes after experimental detachment of the porcine retina. Invest Ophthalmol Vis Sci. 2008; 49(3):1262-1273.
