Purpose: To describe a case of lipemia retinalis, a rare ocular manifestation of hypertriglyceridemia that is characterized by a creamy-white to salmon-colored appearance to the fundus. Methods: A 55-year-old man was referred for an evaluation for diabetic retinopathy and was subsequently found to have marked lipemia retinalis. Results: The patient’s triglyceride levels were 3141 mg/dL; therefore, treatment was initiated with high-intensity statin therapy and lifestyle modifications. At the 3-month follow-up, the patient had significantly reduced triglyceride levels (689 mg/dL) and full resolution of lipemia retinalis. Conclusions: Lipemia retinalis may be an initial finding of a severe systemic problem and a harbinger for more severe, and potentially fatal, consequences. Thus, a complete systemic assessment is warranted for any patient with signs of lipemia retinalis.
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