Sage Journals: Discover world-class research

Abstract

Background:

Reconstruction of the medial patellofemoral ligament (MPFL) has become a popular surgical procedure to address patellofemoral instability. As a consequence of the growing number of MPFL reconstructions performed, a higher rate of failures and revision procedures has been seen.

Purpose:

To perform a failure analysis in patients with patellar redislocation after primary isolated MPFL reconstruction.

Study Design:

Case series; Level of evidence, 4.

Methods:

Patients undergoing revision surgery for reinstability after primary isolated MPFL reconstruction were included. Clinical notes were reviewed to collect demographic data, information on the primary surgery, and the mechanism of patellar redislocation (traumatic vs nontraumatic). Preoperative imaging was analyzed regarding femoral tunnel position and the prevalence of anatomic risk factors (ARFs) associated with patellofemoral instability: trochlear dysplasia (types B through D), patella alta (Caton-Deschamps index >1.2, patellotrochlear index <0.28), lateralization of the tibial tuberosity (tibial tuberosity–trochlear groove distance >20 mm, tibial tuberosity–posterior cruciate ligament [TT-PCL] distance >24 mm), valgus malalignment (mechanical valgus axis >5°), and torsional deformity (internal femoral torsion >25°, external tibial torsion >35°). The prevalence of ARF was compared between patients with traumatic and nontraumatic redislocations and between patients with anatomic and nonanatomic femoral tunnel position.

Results:

A total of 26 patients (69% female) with a mean age of 25 ± 7 years were included. The cause of redislocation was traumatic in 31% and nontraumatic in 69%. Position of the femoral tunnel was considered nonanatomic in 50% of patients. Trochlear dysplasia was the most common ARF with a prevalence of 50%, followed by elevated TT-PCL distance (36%) and valgus malalignment (35%). The median number of ARFs per patient was 3 (range, 0-6), and 65% of patients had 2 or more ARFs. Patients with nontraumatic redislocations showed significantly more ARFs per patient, and the presence of 2 or more ARFs was significantly more common in this group. No significant difference was observed between patients with anatomic versus nonanatomic femoral tunnel position.

Conclusion:

Multiple anatomic risk factors and femoral tunnel malposition are commonly observed in patients with reinstability after primary MPFL reconstruction. Before revision surgery, a focused clinical examination and adequate imaging including radiographs, magnetic resonance imaging (MRI), standing full-leg radiographs, and torsional measurement with computed tomography or MRI are recommended to assess all relevant anatomic parameters to understand an individual patient’s risk profile. During revision surgery, care must be taken to ensure anatomic placement of the femoral tunnel through use of anatomic and/or radiographic landmarks.

Keywords

patellar instability medial patellofemoral ligament MPFL failure revision

Patellofemoral stability is a complex interaction between dynamic muscle action, passive soft tissue restraints, the surface geometry of the patella and trochlea, and limb alignment.^38,71 Therefore, patellofemoral instability is commonly seen as a multifactorial problem.

The medial patellofemoral ligament (MPFL) is the main passive soft tissue restraint against lateral patellar translation during the first 30° of flexion, providing 50% to 60% of the total restraining force.^18,71 MPFL insufficiency is found in most patients with recurrent patellar dislocation.⁵⁸ Therefore, reconstruction of the MPFL has become a popular surgical procedure to address patellofemoral instability with good clinical results and a low redislocation rate.^36,66 However, as a consequence of the increasing number of MPFL reconstructions performed, a higher rate of failures and revision procedures has been seen.^29,59 The main reasons for failed MPFL reconstruction are technical errors and disregard for additional risk factors.^13,56,59,73 With regard to technical errors, femoral tunnel positioning is especially critical because a nonanatomically placed tunnel can cause excessive strain on the graft, leading to stretching and insufficiency of the reconstructed MPFL.^11,37,77,78

Multiple anatomic risk factors (ARFs) predisposing to first-time patellar dislocation and recurrence after first-time dislocation have been described, including trochlear dysplasia, patella alta, lateralization of the tibial tuberosity, valgus malalignment, and torsional deformity.^{1

–4,14,17,22,75} In the presence of 1 or more ARFs, MPFL reconstruction may not be sufficient as an isolated procedure, because the lack of bony constraint and an increased laterally directed force vector may lead to overload of the MPFL graft. Several authors have found an association between the presence of ARFs and unsatisfactory outcomes as well as failure after isolated MPFL reconstruction.^§ Therefore, failure to consider additional risk factors must also be regarded as an important risk factor for redislocation after MPFL reconstruction.^13,56,59,73

Revision surgery after primary MPFL reconstruction is complex, and the results have been reported to be worse than after primary procedures.^13,56 Thorough knowledge of possible risk factors is therefore necessary for adequate preoperative patient assessment and consecutive individualized treatment. However, few studies have specifically analyzed patients after failed MPFL reconstruction .^13,56 The purpose of this study was thus to perform a detailed failure analysis among patients with patellar redislocation after primary MPFL reconstruction. The hypothesis was that ARFs and femoral tunnel malposition are commonly observed in this group of patients.

Methods

Ethical approval for this study was granted from the Technical University Munich. A retrospective cohort design was used to conduct a failure analysis of patients with patellar redislocation after primary isolated MPFL reconstruction.

A chart review was performed using an electronic medical record system to identify all patients undergoing revision surgery after primary MPFL reconstruction between November 2012 and April 2019 at our institution. A total of 83 patients were initially identified. For the purpose of this study, only patients with patellar reinstability, defined as at least 1 patellar redislocation after primary isolated MPFL reconstruction, were included. Excluded were patients undergoing revision surgery for other reasons, such as patellofemoral pain, patellofemoral cartilage defects, and restricted range of motion. Further exclusion criteria were previous or concomitant soft tissue or bony procedures at the ipsilateral knee; absence of preoperative imaging, with conventional radiographs and magnetic resonance imaging (MRI) representing the minimum requirement; and metal implants in the knee area with artifacts on MRI scans or motion artifacts. A flowchart of patient inclusion in the analysis is shown in Figure 1.

Figure 1.

Flowchart of patient inclusion in the analysis. MPFL, medial patellofemoral ligament; MRI, magnetic resonance imaging; ROM, range of motion.

Preoperative (prerevision) workup consisted of a thorough clinical examination and an extended radiographic analysis. In all patients, we performed conventional radiographs of the affected knee in 3 planes as well as MRI. Additional radiographic examination of coronal and torsional limb alignment depended on the clinical examination: Coronal limb alignment was evaluated visually with the patient in a standing position and neutral foot position.³⁵ Patients were asked to adduct their lower limbs until either the knees or ankles touched. Neutral coronal alignment was assumed if knees and ankles touched simultaneously.³⁵ If either the knees or ankles touched first, coronal malalignment was assumed and a standing full-leg radiograph was performed for further evaluation (n = 21; 81% of patients). Screening for abnormal femoral torsion was performed with the patient in the prone position with the hips extended and the knees flexed to 90°. Passive internal and external rotation of the hip was then measured with a goniometer. The maximal external-internal rotation angle was defined as the angle between the tibia and a virtual axis vertical to the ground.¹⁵ In addition, the trochanteric prominence angle test was performed, as described in detail elsewhere.⁶¹ In brief, external rotation of the hip was measured when the greater trochanter was at its most laterally prominent position. Values indicating increased femoral torsion were maximal internal rotation greater than 60°, maximum external rotation less than 30°, and trochanteric prominence angle test greater than 25°.^15,61 Tibial torsion was estimated in the same patient position by measuring the transmalleolar angle, which was defined as the angle between a line perpendicular to the axis connecting the most prominent aspects of the medial and lateral malleolus and the line of the longitudinal axis of the thigh.⁷⁴ If the transmalleolar angle was greater than 35°, increased tibial external torsion was assumed. In the case of clinically abnormal femoral and/or tibial torsion, axial MRI scans that included the hip, knee, and ankle were performed for further evaluation (n = 18; 69% of patients). Furthermore, in patients with unclear position of the femoral tunnel, a computed tomography (CT) scan of the knee with 3-dimensional reconstruction was obtained.

Data Collection

Preoperative clinical notes of all patients were reviewed to collect demographic data, including sex, age at surgery, and body mass index (BMI). Furthermore, relevant information about the primary surgery and the mechanism of injury leading to redislocation of the patella was collected. Redislocations occurring during high-impact sports (eg, football, basketball, downhill skiing) and contact injuries were considered traumatic redislocations, whereas redislocations that occurred during low-impact sports or activities of daily living were considered nontraumatic.

All analyzed images were obtained before revision surgery (after the failed primary isolated MPFL reconstruction). Imaging was analyzed regarding femoral tunnel position and the prevalence of ARFs associated with patellofemoral instability (trochlear dysplasia, patella alta, lateralization of the tibial tuberosity, valgus malalignment, and torsional deformity).^{1

–4,14,17,22,75} All radiographic measurements were performed by 2 orthopaedic residents specifically trained in the measurements obtained in the present study (J.M., D.P.B.). To determine the interobserver reproducibility, intraclass correlation coefficients (ICCs) were calculated.

The following measurements and classifications were performed:

Femoral Tunnel Position

The position of the femoral tunnel was analyzed on lateral radiographs through use of the landmarks described by Schöttle et al⁶⁸ or, if available, on 3-dimensional CT reconstructions according to Fujino et al.³⁰ The femoral tunnel was considered nonanatomic if the center of the tunnel was more than 7 mm away from the Schöttle point, as described by Servien et al.⁷²

Trochlear Dysplasia

The shape of the trochlea was categorized according to the Dejour classification on MRI through use of the 3 most proximal images demonstrating articular cartilage.¹⁶ Significant trochlear dysplasia was defined as a flat or convex trochlea (Dejour type B, C, and D).^48,75

Caton-Deschamps Index (CDI)

The CDI was determined on lateral radiographs as the ratio between the distance from the lower border of the patella to the tibial plateau and the length of the retropatellar surface.⁹ Knees with a ratio greater than 1.2 were considered to have patella alta (pathologic CDI).^9,17

Patellotrochlear Index (PTI)

The PTI was measured on sagittal MRI as described by Biedert and Albrecht.⁸ In contrast to the original protocol, imaging was obtained with the knee in a slightly flexed position instead of a fully extended position. The length ratio between the articular surface of the patella and the articulating trochlea was calculated. A ratio less than 0.28 was considered pathologic.⁹

Tibial Tuberosity–Trochlear Groove (TT-TG) Distance

The TT-TG distance was measured on axial MRI scans as the mediolateral distance between the midpoint of the insertion of the patellar tendon and the trochlear groove.^17,67 A TT-TG distance of greater than 20 mm was considered pathologic.¹⁷

Tibial Tuberosity–Posterior Cruciate Ligament (TT-PCL) Distance

The TT-PCL distance was measured on axial MRI scans as described by Seitlinger et al⁷⁰ and defined as the mediolateral distance between the midpoint of the insertion of the patellar tendon and the medial border of the PCL. A TT-PCL distance of greater than 24 mm was considered pathologic.⁷⁰

Coronal Mechanical Axis

Coronal mechanical alignment was measured on standing full-leg radiographs as the angle between a line from the center of the femoral head to the center of the knee and a line from the center of the ankle to the center of the knee. Positive values indicate a mechanical valgus axis, and a valgus angle greater than 5° was considered pathologic. In patients with no measurement (n = 5; 19% of patients), frontal mechanical axis was considered normal based on the clinical examination described above.

Femoral and Tibial Torsion

Torsion of the lower extremity was assessed on rotational MRI as described by Schneider et al.⁶⁵ Femoral torsion was calculated as the angle between a line through the center of the femoral head and neck and a tangent along the posterior border of the femoral condyles. Tibial torsion was measured as the angle between the dorsal tibial condylar line and a line through the medial and lateral malleolus. For femoral torsion, positive values indicate internal femoral torsion and values greater than 25° were considered pathologic.⁸⁰ For tibial torsion, positive values indicate external tibial torsion and values greater than 35° were considered pathologic.⁸⁰ In patients with no measurement (n = 8; 31% of patients), torsion was considered normal based on the clinical examination described above.

Statistical Analysis

Statistical analysis was performed with SPSS software (version 25.0; IBM-SPSS). Continuous variables were calculated as mean ± SD (normal distribution) or median and range (nonnormal distribution). Categorical variables were reported as count and percentage.

Normal distribution of all data was evaluated with the Kolmogorov-Smirnoff test. For each ARF, the prevalence of pathologic values based on the above-mentioned thresholds was calculated. Furthermore, the total number of ARFs was calculated for each patient (combined prevalence). The number of ARFs per patient and the combined prevalence of ARFs was compared between patients with traumatic versus nontraumatic redislocations and between patients with anatomic versus nonanatomic femoral tunnel position through use of the Fisher exact test, Mann-Whitney U test, or unpaired t test, as appropriate. ICCs were calculated to determine the interobserver reproducibility. ICC values greater than 0.9 were considered excellent, values between 0.8 and 0.9 were considered good, and values less than 0.8 were considered poor.

Results

A total of 26 patients (69% female) with a mean age of 25 ± 7 years were included. The left knee was affected in 54%, and the mean BMI was 24 ± 5 kg/m². The primary MPFL reconstruction was performed at our institution in 46% of patients, whereas 54% of patients underwent MPFL reconstruction elsewhere. MPFL reconstruction was performed with a gracilis tendon autograft in 24 patients (92%) and with a semitendinosus tendon autograft in 2 patients (8%).

The cause of redislocation was traumatic in 31% of patients and nontraumatic in 69%. Position of the femoral tunnel was considered nonanatomic in 50% of patients. ARF measurements and corresponding interobserver ICCs are shown in Table 1, and the prevalence of ARFs is shown in Table 2. In summary, trochlear dysplasia was the most common ARF with a prevalence of 50%, followed by elevated TT-PCL distance (36%) and valgus malalignment (35%).

Table 1

Anatomic Risk Factor Measurements ^a

Anatomic Risk Factor	Mean ± SD or Percentage Distribution	Median (Range)	ICC
Caton-Deschamps index ^b	1.1 ± 0.2	1.1 (0.8 to 1.9)	0.905
Patellotrochlear index ^b	0.37 ± 0.15	0.36 (0.05 to 0.74)	0.872
TT-TG distance, mm ^b	16 ± 6	16 (6 to 29)	0.893
TT-PCL distance, mm ^b	23 ± 5	22 (13 to 35)	0.854
Frontal mechanical axis, deg ^c	3 ± 3	3 (–2 to 6)	0.978
Femoral torsion, deg ^d	18 ± 13	17 (–5 to 49)	0.968
Tibial torsion, deg ^e	32 ± 10	34 (13 to 48)	0.929
Trochlear dysplasia ^b			0.848 ^f
None	19%
Type A	31%
Type B	31%
Type C	15%
Type D	4%

^a ICC, intraclass correlation coefficient; TT-PCL, tibial tuberosity–posterior cruciate ligament; TT-TG, tibial tuberosity–trochlear groove.

^bMeasurements were obtained in 26 patients (100%).

^cMeasurements were obtained in 21 patients (81%); positive values indicate valgus malalignment.

^dMeasurements were obtained in 18 patients (69%); positive values indicate internal femoral torsion.

^eMeasurements were obtained in 18 patients (69%); positive values indicate external tibial torsion.

^fThe ICC was calculated for the 2-type modification of the Dejour classification (no dysplasia and type A dysplasia vs types B, C, and D dysplasia).

Table 2

Prevalence of Anatomic Risk Factors ^a

Anatomic Risk Factor	Prevalence, %
Caton-Deschamps index >1.2 ^b	19
Patellotrochlear index <0.28 ^b	16
TT-TG distance >20 mm ^b	27
TT-PCL distance >24 mm ^b	36
Trochlear dysplasia type B-D ^b	50
Mechanical valgus axis >5° ^c	35
Internal femoral torsion >25° ^d	23
External tibial torsion >35° ^d	31

^a TT-PCL, tibial tuberosity–posterior cruciate ligament; TT-TG, tibial tuberosity–trochlear groove.

^bMeasurements were obtained in 26 patients (100%).

^cMeasurements were obtained in 21 patients (81%). In patients with no measurement, frontal mechanical axis was considered normal based on the clinical examination. The prevalence was calculated for the total study group (n = 26).

^dMeasurements were obtained in 18 patients (69%). In patients with no measurement, torsion was considered normal based on the clinical examination. The prevalence was calculated for the total study group (n = 26).

The combined prevalence of ARFs is summarized in Table 3. The median number of ARFs per patient was 3 (range, 0-6), and 65% of patients had 2 or more ARFs (Figure 2).

Table 3

Combined Prevalence of Anatomic Risk Factors

No. of Anatomic Risk Factors per Patient	Prevalence, %
0	15
1	19
2	15
3	27
4	12
5	8
6	4

Figure 2.

Combined prevalence of anatomic risk factors (ARFs). The majority of patients (65%) had 2 or more ARFs.

The results of the group comparison between patients with a traumatic versus nontraumatic redislocation are shown in Table 4. The group of patients with nontraumatic redislocations showed a significantly higher number of ARFs per patient, and the presence of 2 or more ARFs was significantly more common in this group (P < .001 for both) (Figure 3).

Table 4

Group Comparison Between Traumatic and Nontraumatic Redislocations ^a

	Traumatic	Nontraumatic	P
No. of ARFs per patient, median (range)	1 (0-2)	3 (0-6)	<.001 ^b
Combined prevalence of ARFs, %			<.001 ^b
No ARFs	38	6
1 ARF	50	6
≥2 ARFs	13	89
Femoral tunnel position, %			.673
Anatomic	38	56
Nonanatomic	63	44

^a ARF, anatomic risk factor.

^b Statistically significant difference between both groups.

Figure 3.

Comparison of patients with a traumatic and nontraumatic redislocation. The presence of 2 or more anatomic risk factors (ARFs) was significantly more common in patients with nontraumatic redislocations.

Group comparison between patients with anatomic versus nonanatomic femoral tunnel position did not show any significant differences with regard to the presence of ARFs (P > .05).

Discussion

The most important finding of the present study was that multiple ARFs and femoral tunnel malposition are commonly observed in patients with patellar redislocation after primary MPFL reconstruction. Trochlear dysplasia was the most common ARF, observed in 50% of patients. No ARF was observed in only 15% of patients, whereas 2 or more ARFs were observed in 65%. The group of patients with nontraumatic redislocations had a significantly higher number of ARFs per patient, and the presence of 2 or more ARFs was significantly more common in this group versus patients with traumatic dislocations.

Reconstruction of the MPFL has become a widespread surgical procedure for recurrent patellar dislocation.⁶⁶ One of the most critical steps of MPFL reconstruction is anatomic placement of the femoral tunnel, and several studies have demonstrated significant negative clinical and biomechanical effects of tunnel malposition.^37,59,63,77 In the present study, a nonanatomically placed femoral tunnel was found in 50% of patients. Therefore, femoral tunnel malposition seems to be a common problem in patients with reinstability after primary MPFL reconstruction. This association can be well explained by biomechanical studies. The native MPFL has been found to be nearly isometric between 0° and 110° of knee flexion.⁷⁸ Nonanatomic graft placement, however, has been shown to dramatically alter graft isometry; placement of the attachment site only 5 mm distally or proximally has led to significantly increased length of the MPFL during flexion.⁷⁸ This increased strain on the MPFL graft can cause stretching and elongation of the graft, leading to insufficiency and consecutive redislocation of the patella.¹¹ In other clinical studies, malpositioned femoral tunnels have been associated with postoperative complications,⁸¹ recurrent patellar instability or patellofemoral pain,^37,59 and tunnel widening.⁶⁹ Despite knowledge about the importance of anatomic tunnel placement, the rate of nonanatomic placement is reported to be as high as 60%.^52,72 The femoral MPFL insertion site can be identified fluoroscopically through use of radiographic landmarks on a true lateral knee radiograph or by palpation of anatomic landmarks. Many authors prefer the radiographic method because this technique can be performed percutaneously with very small skin incisions. Several radiographic landmarks have been described in the past,^7,68,78 with the “Schöttle point”⁶⁸ being the most commonly used reference. Despite the widespread use of this method, several authors have questioned its accuracy and have recommended that radiographic landmarks should not be the sole basis for femoral attachment location.^39,62 The most accurate method may therefore be a combination of radiographic and anatomic landmarks.³⁹ The femoral insertion of the MPFL has been reported to be located in between the adductor tubercle and the medial epicondyle, with a closer relationship to the adductor tubercle (2 mm anterior and 4 mm distal, according to LaPrade et al⁴³).

Patellofemoral instability must be considered a multifactorial problem because patellofemoral stability depends on the interaction of dynamic and static soft tissue restraints, the surface geometry of the patella and trochlea, and limb alignment. Increasing evidence shows that the bony geometry and limb alignment play a major role in patellofemoral instability. Several studies have identified multiple ARFs predisposing to first-time patellar dislocation and recurrence after first-time dislocation, including trochlear dysplasia, patella alta, lateralization of the tibial tuberosity, valgus malalignment, and torsional deformity.^{1

–4,14,17,22,75} Whereas some authors have found good clinical outcomes and low redislocation rates after isolated MPFL reconstruction even in the presence of ARFs,^{24,49,51,60,76} other authors have found a correlation between ARFs and unsatisfactory outcomes and failure after MPFL reconstruction.^∥ Therefore, additional stabilization procedures are increasingly performed in combination with MPFL reconstruction, such as trochleoplasty,^5,6,10,34,54 medialization or distalization of the tibial tuberosity,^12,26,44,50 and osteotomies to correct torsion and/or valgus malalignment.^{19

–23,27,28,55} The results of the current study suggest that the presence of ARFs is related to failure after MPFL reconstruction, as only 15% of patients had no ARFs, whereas 2 or more ARFs were observed in 65% of patients.

In the present study, trochlear dysplasia was the most common ARF, with a prevalence of 50%, followed by elevated TT-PCL distance (36%) and valgus malalignment (35%). Trochlear dysplasia and a lateralized tibial tuberosity (defined as a pathologic TT-PCL or TT-TG distance) are well-accepted risk factors for recurrence after first-time patellar dislocation and for failure after MPFL reconstruction.^{4,14,33,37,42,75,82} Both factors are included in well-established risk scores such as the patellar instability severity score.⁴ The role of valgus malalignment and torsional deformities in patellofemoral instability is less well understood. However, increasing evidence shows that both valgus and torsional malalignment promote patellar instability. Valgus malalignment has been shown to alter the force vector on the patella by increasing the Q-angle, leading to lateralization of the patella.^19,28,53,57 In patients with isolated MPFL reconstruction but uncorrected valgus malalignment, the increased laterally directed force vector may lead to failure of the MPFL graft due to repetitive overloading. The same is true for increased internal femoral torsion and increased external tibial torsion. Biomechanical studies have demonstrated that both deformities result in lateralization of the patella and abnormal lateral patellofemoral loads.^{31,40,41,45
–47} Furthermore, Kaiser et al⁴¹ showed that isolated MPFL reconstruction cannot restore patellar stability in cases with higher degrees of internal femoral torsion. In the present study, increased internal femoral torsion and increased external tibial torsion were found in 23% and 31% of patients, respectively. Therefore, assessment of frontal and torsional alignment is important in patients with patellar instability, especially after failed MPFL reconstruction.

Only a few studies have specifically analyzed patients after failed MPFL reconstruction. Nelitz et al⁵⁶ analyzed 19 patients who underwent revision surgery after MPFL reconstruction because of disabling pain and/or loss of flexion (n = 13) or recurrent instability (n = 6). Those investigators observed 3 main reasons for failure after MPFL reconstruction: failure to consider ARFs, technical errors, and inappropriate patient selection. Trochlear dysplasia was the most common ARF, which was observed in 5 of 6 patients with recurrent instability. In 2 patients, concomitant excessive femoral anteversion was detected. Femoral tunnel malposition was commonly observed in patients with pain and loss of flexion. Chatterton et al¹³ evaluated 23 patients undergoing revision surgery after failed primary MPFL reconstruction and compared patient outcomes with 224 primary MPFL reconstructions. Those authors found an incorrectly placed femoral tunnel in 67% of patients with failed MPFL reconstruction. Severe trochlear dysplasia types C and D were seen in 36% of patients with failed MPFL reconstruction compared with 30% of patients with primary MPFL reconstruction. However, this difference was not statistically significant. Subjective outcomes did not improve significantly after revision MPFL reconstruction, and the final results were poorer in the revision group than in the primary MPFL group.

The current study has several limitations. First, this was a descriptive study without a control group. Therefore, we were unable to prove that the identified ARFs were causative for failure. Second, it remains unclear which factors are the most relevant. Therefore, no conclusions about surgical decision making could be drawn. Further research is necessary to determine to what extent each factor contributes to MPFL failure. Third, valgus alignment and torsion were assessed only in patients with conspicuous clinical examination. In patients without radiographic evaluation, leg axis and torsion were considered normal for data analysis. Therefore, valgus and torsional malalignment may have been underestimated in the present study. Fourth, there are other possible factors for failure that could not be assessed in the present study, such as surgeon experience, initial tension of the graft, failure of the graft to incorporate, abrasion of the graft at the femoral or tibial attachment site, and overly aggressive rehabilitation.

Despite these limitations, the findings of the present study have several implications for clinical practice. First, extensive knowledge of both anatomic and radiographic landmarks for anatomic femoral tunnel placement is necessary in order to avoid tunnel malposition.^7,30,39,67 Second, given the high prevalence and combined prevalence of ARFs, a focused clinical examination and adequate imaging are crucial to assess all relevant anatomic parameters in order to understand an individual patient’s risk profile. We recommend conventional radiographs of the affected knee in all 3 planes as well as MRI in all cases. Additional radiographic measurement of coronal alignment and torsion is recommended if the clinical examination as described in the Methods section is conspicuous. If coronal malalignment is suspected, an additional standing full-leg radiograph should be performed. In the case of conspicuous internal rotation of the hip or external rotation of the lower leg, torsion of the femur and tibia should be assessed with hip-knee-ankle CT or MRI.⁶⁵ After all ARFs have been identified, a tailored approach should be considered. In our opinion, isolated revision MPFL reconstruction should be limited for patients without ARFs. In accordance with other authors, we recommend additional stabilization procedures such as trochleoplasty,^5,6,10,34,54 osteotomies to correct torsion and/or valgus alignment,^{19

–23,27,28,55} or transfer of the tibial tuberosity^12,26,44,50 in order to address all possible associated patellar instability risk factors. This is especially important in revision cases because isolated MPFL reconstruction has been shown to be insufficient. Our treatment algorithm for patients with reinstability after primary MPFL reconstruction is presented in Figure 4.

Figure 4.

Treatment algorithm for patients with reinstability after primary MPFL reconstruction. CDI, Caton-Deschamps index; CT, computed tomography; DFO, distal femoral osteotomy; HTO, high tibial osteotomy; MPFL, medial patellofemoral ligament; MRI, magnetic resonance imaging; PTI, patellotrochlear index; TT-PCL, tibial tuberosity–posterior cruciate ligament distance; TT-TG, tibial tuberosity–trochlear groove distance.

An individualized treatment plan is still necessary because it remains unknown when to surgically correct ARFs in isolation or in combination. In most cases, complex corrections are required, and extensive experience in patellofemoral surgery is necessary to achieve satisfying outcomes for patients.

Conclusion

Multiple ARFs and femoral tunnel malposition are commonly observed in patients with reinstability after primary MPFL reconstruction. A focused clinical examination and adequate imaging including radiographs, MRI, standing full-leg radiographs, and torsional measurement with CT or MRI are recommended to assess all relevant anatomic parameters in order to understand an individual patient’s risk profile. During revision surgery, care must be taken to ensure anatomic placement of the femoral tunnel through use of anatomic and/or radiographic landmarks.

Footnotes

Notes

References

Arendt

Askenberger

Agel

Tompkins

. Risk of redislocation after primary patellar dislocation: a clinical prediction model based on magnetic resonance imaging variables. Am J Sports Med. 2018;46(14):3385–3390.

Arendt

England

Agel

Tompkins

. An analysis of knee anatomic imaging factors associated with primary lateral patellar dislocations. Knee Surg Sports Traumatol Arthrosc. 2017;25(10):3099–3107.

Askenberger

Janarv

Finnbogason

Arendt

. Morphology and anatomic patellar instability risk factors in first-time traumatic lateral patellar dislocations: a prospective magnetic resonance imaging study in skeletally immature children. Am J Sports Med. 2017;45(1):50–58.

Balcarek

Oberthur

Hopfensitz

, et al.

Which patellae are likely to redislocate?

Knee Surg Sports Traumatol Arthrosc. 2014;22(10):2308–2314.

Balcarek

Zimmermann

. Deepening trochleoplasty and medial patellofemoral ligament reconstruction normalize patellotrochlear congruence in severe trochlear dysplasia. Bone Joint J. 2019;101(3):325–330.

Banke

Kohn

Meidinger

, et al. Combined trochleoplasty and MPFL reconstruction for treatment of chronic patellofemoral instability: a prospective minimum 2-year follow-up study. Knee Surg Sports Traumatol Arthrosc. 2014;22(11):2591–2598.

Barnett

Howells

Burston

Ansari

Clark

Eldridge

. Radiographic landmarks for tunnel placement in reconstruction of the medial patellofemoral ligament. Knee Surg Sports Traumatol Arthrosc. 2012;20(12):2380–2384.

Biedert

Albrecht

. The patellotrochlear index: a new index for assessing patellar height. Knee Surg Sports Traumatol Arthrosc. 2006;14(8):707–712.

Biedert

Tscholl

. Patella alta: a comprehensive review of current knowledge. Am J Orthop (Belle Mead NJ). 2017;46(6):290–300.

10.

Blond

Haugegaard

. Combined arthroscopic deepening trochleoplasty and reconstruction of the medial patellofemoral ligament for patients with recurrent patella dislocation and trochlear dysplasia. Knee Surg Sports Traumatol Arthrosc. 2014;22(10):2484–2490.

11.

Bollier

Fulkerson

Cosgarea

Tanaka

. Technical failure of medial patellofemoral ligament reconstruction. Arthroscopy. 2011;27(8):1153–1159.

12.

Boutefnouchet

Downham

Bassett

Thompson

Sprowson

. The efficacy of medial patellofemoral ligament reconstruction combined with tibial tuberosity transfer in the treatment of patellofemoral instability. Knee Surg Relat Res. 2016;28(2):99–109.

13.

Chatterton

Nielsen

Sorensen

Lind

. Clinical outcomes after revision surgery for medial patellofemoral ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2018;26(3):739–745.

14.

Christensen

Sanders

Pareek

Mohan

Dahm

Krych

. Risk factors and time to recurrent ipsilateral and contralateral patellar dislocations. Am J Sports Med. 2017;45(9):2105–2110.

15.

Crane

. Femoral torsion and its relation to toeing-in and toeing-out. J Bone Joint Surg Am. 1959;41(3):421–428.

16.

Dejour

Saggin

. The sulcus deepening trochleoplasty—the Lyon’s procedure. Int Orthop. 2010;34(2):311–316.

17.

Dejour

Walch

Nove-Josserand

Guier

. Factors of patellar instability: an anatomic radiographic study. Knee Surg Sports Traumatol Arthrosc. 1994;2(1):19–26.

18.

Desio

Burks

Bachus

. Soft tissue restraints to lateral patellar translation in the human knee. Am J Sports Med. 1998;26(1):59–65.

19.

Dickschas

Ferner

Lutter

Gelse

Harrer

Strecker

. Patellofemoral dysbalance and genua valga: outcome after femoral varisation osteotomies. Arch Orthop Trauma Surg. 2018;138(1):19–25.

20.

Dickschas

Harrer

Pfefferkorn

Strecker

. Operative treatment of patellofemoral maltracking with torsional osteotomy. Arch Orthop Trauma Surg. 2012;132(3):289–298.

21.

Dickschas

Tassika

Lutter

Harrer

Strecker

. Torsional osteotomies of the tibia in patellofemoral dysbalance. Arch Orthop Trauma Surg. 2017;137(2):179–185.

22.

Diederichs

Kohlitz

Kornaropoulos

Heller

Vollnberg

Scheffler

. Magnetic resonance imaging analysis of rotational alignment in patients with patellar dislocations. Am J Sports Med. 2013;41(1):51–57.

23.

Drexler

Dwyer

Dolkart

, et al. Tibial rotational osteotomy and distal tuberosity transfer for patella subluxation secondary to excessive external tibial torsion: surgical technique and clinical outcome. Knee Surg Sports Traumatol Arthrosc. 2014;22(11):2682–2689.

24.

Erickson

Nguyen

Gasik

Gruber

Brady

Shubin Stein

. Isolated medial patellofemoral ligament reconstruction for patellar instability regardless of tibial tubercle-trochlear groove distance and patellar height: outcomes at 1 and 2 years. Am J Sports Med. 2019;47(6):1331–1337.

25.

Franciozi

Ambra

Albertoni

, et al. Increased femoral anteversion influence over surgically treated recurrent patellar instability patients. Arthroscopy. 2017;33(3):633–640.

26.

Franciozi

Ambra

Albertoni

LJB

, et al. Anteromedial tibial tubercle osteotomy improves results of medial patellofemoral ligament reconstruction for recurrent patellar instability in patients with tibial tuberosity-trochlear groove distance of 17 to 20 mm. Arthroscopy. 2019;35(2):566–574.

27.

Frings

Krause

Akoto

Frosch

. Clinical results after combined distal femoral osteotomy in patients with patellar maltracking and recurrent dislocations. J Knee Surg. 2019;32(9):924–933.

28.

Frings

Krause

Akoto

Wohlmuth

Frosch

. Combined distal femoral osteotomy (DFO) in genu valgum leads to reliable patellar stabilization and an improvement in knee function. Knee Surg Sports Traumatol Arthrosc. 2018;26(12):3572–3581.

29.

Frosch

Schmeling

. A new classification system of patellar instability and patellar maltracking. Arch Orthop Trauma Surg. 2016;136(4):485–497.

30.

Fujino

Tajima

Yan

, et al. Morphology of the femoral insertion site of the medial patellofemoral ligament. Knee Surg Sports Traumatol Arthrosc. 2015;23(4):998–1003.

31.

Hefzy

Jackson

Saddemi

Hsieh

. Effects of tibial rotations on patellar tracking and patello-femoral contact areas. J Biomed Eng. 1992;14(4):329–343.

32.

Hiemstra

Kerslake

Lafave

. Quality-of-life outcomes of patients following patellofemoral stabilization surgery: the influence of trochlear dysplasia. J Knee Surg. 2017;30(9):887–893.

33.

Hiemstra

Kerslake

Loewen

Lafave

. Effect of trochlear dysplasia on outcomes after isolated soft tissue stabilization for patellar instability. Am J Sports Med. 2016;44(6):1515–1523.

34.

Hiemstra

Peterson

Youssef

Soliman

Banfield

Ayeni

. Trochleoplasty provides good clinical outcomes and an acceptable complication profile in both short and long-term follow-up. Knee Surg Sports Traumatol Arthrosc. 2019;27(9):2967–2983.

35.

Hinman

May

Crossley

. Is there an alternative to the full-leg radiograph for determining knee joint alignment in osteoarthritis? Arthritis Rheum. 2006;55(2):306–313.

36.

Hinterwimmer

Imhoff

Minzlaff

, et al. Anatomical two-bundle medial patellofemoral ligament reconstruction with hardware-free patellar graft fixation: technical note and preliminary results. Knee Surg Sports Traumatol Arthrosc. 2013;21(9):2147–2154.

37.

Hopper

Leach

Rooney

Walker

Blyth

. Does degree of trochlear dysplasia and position of femoral tunnel influence outcome after medial patellofemoral ligament reconstruction? Am J Sports Med. 2014;42(3):716–722.

38.

Imhoff

Funke

Muench

, et al. The complexity of bony malalignment in patellofemoral disorders: femoral and tibial torsion, trochlear dysplasia, TT-TG distance, and frontal mechanical axis correlate with each other. Knee Surg Sports Traumatol Arthrosc. 2020;28(3):897–904.

39.

Izadpanah

Meine

Kubosch

, et al. Fluoroscopic guided tunnel placement during medial patellofemoral ligament reconstruction is not accurate in patients with severe trochlear dysplasia. Knee Surg Sports Traumatol Arthrosc. 2020;28(3):759–766.

40.

Kaiser

Schmoelz

Schoettle

Zwierzina

Heinrichs

Attal

. Increased internal femoral torsion can be regarded as a risk factor for patellar instability—a biomechanical study. Clin Biomech (Bristol, Avon). 2017;47:103–109.

41.

Kaiser

Schmoelz

Schöttle

Heinrichs

Zwierzina

Attal

. Isolated medial patellofemoral ligament reconstruction for patella instability is insufficient for higher degrees of internal femoral torsion. Knee Surg Sports Traumatol Arthrosc. 2019;27(3):758–765.

42.

Kita

Tanaka

Toritsuka

, et al. Factors affecting the outcomes of double-bundle medial patellofemoral ligament reconstruction for recurrent patellar dislocations evaluated by multivariate analysis. Am J Sports Med. 2015;43(12):2988–2996.

43.

LaPrade

Engebretsen

Johansen

Wentorf

Engebretsen

. The anatomy of the medial part of the knee. J Bone Joint Surg Am. 2007;89(9):2000–2010.

44.

Lee

Wang

Kang

Kim

Haque

Lee

. The clinical and radiological results of individualized surgical treatment depending on pathologic abnormalities in recurrent patellar dislocation: low recurrence rate, but unintended patella baja. Knee Surg Sports Traumatol Arthrosc. 2018;26(9):2558–2567.

45.

Lee

Anzel

Bennett

Pang

Kim

. The influence of fixed rotational deformities of the femur on the patellofemoral contact pressures in human cadaver knees. Clin Orthop Relat Res. 1994;302:69–74.

46.

Lee

Morris

Csintalan

. The influence of tibial and femoral rotation on patellofemoral contact area and pressure. J Orthop Sports Phys Ther. 2003;33(11):686–693.

47.

Lee

Yang

Sandusky

McMahon

. The effects of tibial rotation on the patellofemoral joint: assessment of the changes in in situ strain in the peripatellar retinaculum and the patellofemoral contact pressures and areas. J Rehabil Res Dev. 2001;38(5):463–469.

48.

Lippacher

Dejour

Elsharkawi

, et al. Observer agreement on the Dejour trochlear dysplasia classification: a comparison of true lateral radiographs and axial magnetic resonance images. Am J Sports Med. 2012;40(4):837–843.

49.

Liu

Brady

Kalbian

, et al. Clinical outcomes after isolated medial patellofemoral ligament reconstruction for patellar instability among patients with trochlear dysplasia. Am J Sports Med. 2018;46(4):883–889.

50.

Lobner

Krauss

Reichwein

Patzer

Nebelung

Venjakob

. Surgical treatment of patellar instability: clinical and radiological outcome after medial patellofemoral ligament reconstruction and tibial tuberosity medialisation. Arch Orthop Trauma Surg. 2017;137(8):1087–1095.

51.

Matsushita

Kuroda

Oka

Matsumoto

Takayama

Kurosaka

. Clinical outcomes of medial patellofemoral ligament reconstruction in patients with an increased tibial tuberosity-trochlear groove distance. Knee Surg Sports Traumatol Arthrosc. 2014;22(10):2438–2444.

52.

McCarthy

Ridley

Bollier

Wolf

Albright

Amendola

. Femoral tunnel placement in medial patellofemoral ligament reconstruction. Iowa Orthop J. 2013;33:58–63.

53.

McWalter

Cibere

MacIntyre

Nicolaou

Schulzer

Wilson

. Relationship between varus-valgus alignment and patellar kinematics in individuals with knee osteoarthritis. J Bone Joint Surg Am. 2007;89(12):2723–2731.

54.

Nelitz

Dreyhaupt

Lippacher

. Combined trochleoplasty and medial patellofemoral ligament reconstruction for recurrent patellar dislocations in severe trochlear dysplasia: a minimum 2-year follow-up study. Am J Sports Med. 2013;41(5):1005–1012.

55.

Nelitz

Dreyhaupt

Williams

Dornacher

. Combined supracondylar femoral derotation osteotomy and patellofemoral ligament reconstruction for recurrent patellar dislocation and severe femoral anteversion syndrome: surgical technique and clinical outcome. Int Orthop. 2015;39(12):2355–2362.

56.

Nelitz

Williams

Lippacher

Reichel

Dornacher

. Analysis of failure and clinical outcome after unsuccessful medial patellofemoral ligament reconstruction in young patients. Int Orthop. 2014;38(11):2265–2272.

57.

Nha

, et al. Surgical treatment with closing-wedge distal femoral osteotomy for recurrent patellar dislocation with genu valgum. Am J Sports Med. 2018;46(7):1632–1640.

58.

Nomura

. Classification of lesions of the medial patello-femoral ligament in patellar dislocation. Int Orthop. 1999;23(5):260–263.

59.

Parikh

Nathan

Wall

Eismann

. Complications of medial patellofemoral ligament reconstruction in young patients. Am J Sports Med. 2013;41(5):1030–1038.

60.

Pesenti

Ollivier

Escudier

, et al.

Medial patellofemoral ligament reconstruction in children: do osseous abnormalities matter?

Int Orthop. 2018;42(6):1357–1362.

61.

Ruwe

Gage

Ozonoff

DeLuca

. Clinical determination of femoral anteversion: a comparison with established techniques. J Bone Joint Surg Am. 1992;74(6):820–830.

62.

Sanchis-Alfonso

Ramirez-Fuentes

Montesinos-Berry

Aparisi-Rodriguez

Marti-Bonmati

. Does radiographic location ensure precise anatomic location of the femoral fixation site in medial patellofemoral ligament surgery? Knee Surg Sports Traumatol Arthrosc. 2016;24(9):2838–2844.

63.

Sanchis-Alfonso

Ramirez-Fuentes

Montesinos-Berry

Domenech

Marti-Bonmati

. Femoral insertion site of the graft used to replace the medial patellofemoral ligament influences the ligament dynamic changes during knee flexion and the clinical outcome. Knee Surg Sports Traumatol Arthrosc. 2017;25(8):2433–2441.

64.

Sappey-Marinier

Sonnery-Cottet

O’Loughlin

, et al. Clinical outcomes and predictive factors for failure with isolated MPFL reconstruction for recurrent patellar instability: a series of 211 reconstructions with a minimum follow-up of 3 years. Am J Sports Med. 2019;47(6):1323–1330.

65.

Schneider

Laubenberger

Jemlich

Groene

Weber

Langer

. Measurement of femoral antetorsion and tibial torsion by magnetic resonance imaging. Br J Radiol. 1997;70(834):575–579.

66.

Schneider

Grawe

Magnussen

, et al. Outcomes after isolated medial patellofemoral ligament reconstruction for the treatment of recurrent lateral patellar dislocations: a systematic review and meta-analysis. Am J Sports Med. 2016;44(11):2993–3005.

67.

Schoettle

Zanetti

Seifert

Pfirrmann

Fucentese

Romero

. The tibial tuberosity-trochlear groove distance: a comparative study between CT and MRI scanning. Knee. 2006;13(1):26–31.

68.

Schöttle

Schmeling

Rosenstiel

Weiler

. Radiographic landmarks for femoral tunnel placement in medial patellofemoral ligament reconstruction. Am J Sports Med. 2007;35(5):801–804.

69.

Schuttler

Hoeger

Heyse

, et al. Femoral tunnel widening is associated with tunnel malposition but not with clinical failure after medial patellofemoral ligament reconstruction with a free gracilis tendon graft. Arch Orthop Trauma Surg. 2018;138(7):979–984.

70.

Seitlinger

Scheurecker

Hogler

Labey

Innocenti

Hofmann

. Tibial tubercle-posterior cruciate ligament distance: a new measurement to define the position of the tibial tubercle in patients with patellar dislocation. Am J Sports Med. 2012;40(5):1119–1125.

71.

Senavongse

Amis

. The effects of articular, retinacular, or muscular deficiencies on patellofemoral joint stability: a biomechanical study in vitro. J Bone Joint Surg Br. 2005;87(4):577–582.

72.

Servien

Fritsch

Lustig

, et al. In vivo positioning analysis of medial patellofemoral ligament reconstruction. Am J Sports Med. 2011;39(1):134–139.

73.

Shah

Howard

Flanigan

Brophy

Carey

Lattermann

. A systematic review of complications and failures associated with medial patellofemoral ligament reconstruction for recurrent patellar dislocation. Am J Sports Med. 2012;40(8):1916–1923.

74.

Staheli

Corbett

Wyss

King

. Lower-extremity rotational problems in children: normal values to guide management. J Bone Joint Surg Am. 1985;67(1):39–47.

75.

Steensen

Bentley

Trinh

Backes

Wiltfong

. The prevalence and combined prevalences of anatomic factors associated with recurrent patellar dislocation: a magnetic resonance imaging study. Am J Sports Med. 2015;43(4):921–927.

76.

Steiner

Torga-Spak

Teitge

. Medial patellofemoral ligament reconstruction in patients with lateral patellar instability and trochlear dysplasia. Am J Sports Med. 2006;34(8):1254–1261.

77.

Stephen

Kaider

Lumpaopong

Deehan

Amis

. The effect of femoral tunnel position and graft tension on patellar contact mechanics and kinematics after medial patellofemoral ligament reconstruction. Am J Sports Med. 2014;42(2):364–372.

78.

Stephen

Lumpaopong

Deehan

Kader

Amis

. The medial patellofemoral ligament: location of femoral attachment and length change patterns resulting from anatomic and nonanatomic attachments. Am J Sports Med. 2012;40(8):1871–1879.

79.

Stevens

Gililland

Anderson

Mickelson

Nielson

Klatt

. Success of torsional correction surgery after failed surgeries for patellofemoral pain and instability. Strategies Trauma Limb Reconstr. 2014;9(1):5–12.

80.

Strecker

Keppler

Gebhard

Kinzl

. Length and torsion of the lower limb. J Bone Joint Surg Br. 1997;79(6):1019–1023.

81.

Tscholl

Ernstbrunner

Pedrazzoli

Fucentese

. The relationship of femoral tunnel positioning in medial patellofemoral ligament reconstruction on clinical outcome and postoperative complications. Arthroscopy. 2018;34(8):2410–2416.

82.

Wagner

Pfalzer

Hingelbaum

Huth

Mauch

Bauer

. The influence of risk factors on clinical outcomes following anatomical medial patellofemoral ligament (MPFL) reconstruction using the gracilis tendon. Knee Surg Sports Traumatol Arthrosc. 2013;21(2):318–324.

Failure Analysis in Patients With Patellar Redislocation After Primary Isolated Medial Patellofemoral Ligament Reconstruction

Abstract

Background:

Purpose:

Study Design:

Methods:

Results:

Conclusion:

Keywords

Methods

Data Collection

Femoral Tunnel Position

Trochlear Dysplasia

Caton-Deschamps Index (CDI)

Patellotrochlear Index (PTI)

Tibial Tuberosity–Trochlear Groove (TT-TG) Distance

Tibial Tuberosity–Posterior Cruciate Ligament (TT-PCL) Distance

Coronal Mechanical Axis

Femoral and Tibial Torsion

Statistical Analysis

Results

Discussion

Conclusion

Footnotes

Notes

References