Abstract
KM Singleton, SF Morris, a Freiberg. Keratoacanthoma in the immunocompromised patient - Surgical concerns. Can J Plast Surg 1994;2(3): 108-112. It is well known that clinical and histological differentiation between keratoacanthoma and squamous cell carcinoma is often difficult. The two lesions share many common features, but have very different outcomes. Both occur with increased frequency in immunosuppressed patients. This report documents two cases of histologically confirmed keratoacanthoma in immunosuppressed patients. These lesions were excised but had frequent recurrences and in both cases underwent histologically proven malignant transformation. The purpose of this report is to demonstrate the potentially aggressive nature of keratoacanthomas in the immunocompromised patient.
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