Multiple Adaptive Attention-Bias-Modification Programs to Alter Normative Increase in the Error-Related Negativity in Adolescents

Abstract

In the current article, we examined the impact of two home-delivered attentional-bias-modification (ABM) programs on a biomarker of anxiety (i.e., the error-related negativity [ERN]). The ERN is sensitivity to ABM-related changes; however, it is unclear whether ABM exerts its influence on the ERN and anxiety by increasing general attentional control or by disengaging spatial allocation of attention. In this study, we measured the ERN, anxiety, attention bias, and attention control before and after two versions of ABM training and a waitlist control group in 546 adolescents. An ABM designed to increase attention control modulated the ERN but had no impact on anxiety. An ABM designed to reduce attentional bias changed bias and self-reported anxiety in youths but had no impact on the ERN or parent-reported anxiety. These results suggest that the ERN and normative anxiety may be modified using attention training.

Keywords

anxiety ERN ABM developmental psychopathology

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References

Amir

Kuckertz

J. M.

Strege

M. V.

(2016). A pilot study of an adaptive, idiographic, and multi-component attention bias modification program for social anxiety disorder. Cognitive Therapy and Research, 40(5), 661–671. https://doi.org/10.1007/s10608-016-9781-1

Amir

Weber

Beard

Bomyea

Taylor

C. T.

(2008). The effect of a single-session attention modification program on response to a public-speaking challenge in socially anxious individuals. Journal of Abnormal Psychology, 117(4), 860–868. https://doi.org/10.1037/a0013445

Appelbaum

Cooper

Kline

R. B.

Mayo-Wilson

Nezu

A. M.

Rao

S. M.

(2018). Journal article reporting standards for quantitative research in psychology: The APA Publications and Communications Board task force report. The American Psychologist, 73(1), 3–25. https://doi.org/10.1037/amp0000191

Bar-Haim

(2010). Research review: Attention bias modification (ABM): A novel treatment for anxiety disorders. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 51(8), 859–870. https://doi.org/10.1111/j.1469-7610.2010.02251.x

Bates

Machler

Walker

(2014) Fitting linear mixed-effects models using Ime4. Journal of Statistical Software, 67(1), 1–48.

Beard

(2011). Cognitive bias modification for anxiety: Current evidence and future directions. Expert Review of Neurotherapeutics, 11(2), 299–311. https://doi.org/10.1586/ern.10.194

Beesdo

Bittner

Pine

D. S.

Stein

M. B.

Höfler

Lieb

Wittchen

H. U.

(2007). Incidence of social anxiety disorder and the consistent risk for secondary depression in the first three decades of life. Archives of General Psychiatry, 64(8), 903–912. https://doi.org/10.1001/archpsyc.64.8.903

Beesdo

Knappe

Pine

D. S.

(2009). Anxiety and anxiety disorders in children and adolescents: Developmental issues and implications for DSM-V. Psychiatric Clinics of North America, 32(3), 483–524. https://doi.org/10.1016/j.psc.2009.06.002

Birmaher

Brent

D. A.

Chiappetta

Bridge

Monga

Baugher

(1999). Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): A replication study. Journal of the American Academy of Child and Adolescent Psychiatry, 38(10), 1230–1236. https://doi.org/10.1097/00004583-199910000-00011

10.

Bishop

S. J.

(2008). Neural mechanisms underlying selective attention to threat. Annals of the New York Academy of Sciences, 1129, 141–152. https://doi.org/10.1196/annals.1417.016

11.

Bittner

Egger

H. L.

Erkanli

Jane Costello

Foley

D. L.

Angold

(2007). What do childhood anxiety disorders predict? Journal of Child Psychology and Psychiatry, and Allied Disciplines, 48, 1174–1183. https://doi.org/10.1111/j.1469-7610.2007.01812.x

12.

Brain Vision ActiChamp System. (2016). Brain Products GmbH.

13.

Bretherton

P. M.

Eysenck

M. W.

Richards

Holmes

(2020). Target and distractor processing and the influence of load on the allocation of attention to task-irrelevant threat. Neuropsychologia, 145, Article 106491. https://doi.org/10.1016/j.neuropsychologia.2017.09.009

14.

Britton

J. C.

Bar-Haim

Clementi

M. A.

Sankin

L. S.

Chen

Shechner

Norcross

M. A.

Spiro

C. N.

Lindstrom

K. M.

Pine

D. S.

(2013). Training-associated changes and stability of attention bias in youth: Implications for Attention Bias Modification Treatment for pediatric anxiety. Developmental Cognitive Neuroscience, 4, 52–64. https://doi.org/10.1016/j.dcn.2012.11.001

15.

Britton

M. K.

Anderson

B. A.

(2021). Attentional avoidance of threatening stimuli. Psychological Research, 85(1), 82–90. https://doi.org/10.1007/s00426-019-01255-6

16.

Brown

C. S.

Amir

(2022). The moderating effect of anxiety diagnosis on the relationship between error-related negativity and anxiety sensitivity cognitive concerns. Biological Psychology, 175, Article 108443. https://doi.org/10.1016/j.biopsycho.2022.108443

17.

Browning

Holmes

E. A.

Harmer

C. J.

(2010). The modification of attentional bias to emotional information: A review of the techniques, mechanisms, and relevance to emotional disorders. Cognitive, Affective & Behavioral Neuroscience, 10(1), 8–20. https://doi.org/10.3758/CABN.10.1.8

18.

Carlson

Fang

Andrzejewski

(2021). No change in electrocortical measures of performance monitoring in high trait anxious individuals following multi-session attention bias modification training. NeuroImage: Reports, 1(4), Article 100067. https://doi.org/10.1016/j.ynirp.2021.100067

19.

Clayson

P. E.

Baldwin

S. A.

Larson

M. J.

(2021). Evaluating the internal consistency of subtraction-based and residualized difference scores: Considerations for psychometric reliability analyses of event-related potentials. Psychophysiology, 58(4), Article 13762. https://doi.org/10.1111/psyp.13762

20.

Cosi

Canals

Hernández-Martinez

Vigil-Colet

(2010). Parent-child agreement in SCARED and its relationship to anxiety symptoms. Journal of Anxiety Disorders, 24(1), 129–133. https://doi.org/10.1016/j.janxdis.2009.09.008

21.

Derryberry

Reed

M. A.

(2002). Anxiety-related attentional biases and their regulation by attentional control. Journal of Abnormal Psychology, 111(2), 225–236. https://doi.org/10.1037//0021-843x.111.2.225

22.

EasyCap GmbH. (n.d.). https://www.easycap.de/products/

23.

Endrass

Riesel

Kathmann

Buhlmann

(2014). Performance monitoring in obsessive-compulsive disorder and social anxiety disorder. Journal of Abnormal Psychology, 123(4), 705–714. https://doi.org/10.1037/abn0000012

24.

Eriksen

(1974). Effects of noise letters upon the identification of a target letter in a nonsearch task;. Attention, Perception, & Psychophysics, 16(1), 143–149. https://doi.org/10.3758/bf03203267

25.

European Medicines Agency. (2015). Adjustment for baseline covariates in clinical trials (Reference No. EMA/CHMP/295050/2013). https://www.ema.europa.eu/en/adjustment-baseline-covariates-clinical-trials

26.

Falkenstein

Hoormann

Christ

Hohnsbein

(2000). ERP components on reaction errors and their functional significance: A tutorial. Biological Psychology, 51(2–3), 87–107. https://doi.org/10.1016/s0301-0511(99)00031-9

27.

Fan

McCandliss

B. D.

Sommer

Raz

Posner

M. I.

(2002). Testing the efficiency and independence of attentional networks. Journal of Cognitive Neuroscience, 14(3), 340–347. https://doi.org/10.1162/089892902317361886

28.

Finch

A. J.

Saylor

C. F.

Edwards

G. L.

(1985). Children’s depression inventory: Sex and grade norms for normal children. Journal of Consulting and Clinical Psychology, 53(3), 424–425. https://doi.org/10.1037//0022-006x.53.3.424

29.

Gehring

W. J.

Goss

Coles

M. G. H.

Meyer

D. E.

Donchin

(1993). A neural system for error detection and compensation. Psychological Science, 4(6), 385–390. https://doi.org/10.1111/j.1467-9280.1993.tb00586.x

30.

Gratton

Coles

M. G. H.

Donchin

(1983). A new method for off-line removal of ocular artifact. Electroencephalography and Clinical Neurophysiology, 55(4), 468–484. https://doi.org/10.1016/0013-4694(83)90135-9

31.

Hajcak

Franklin

M. E.

Foa

E. B.

Simons

R. F.

(2008). Increased error-related brain activity in pediatric obsessive-compulsive disorder before and after treatment. American Journal of Psychiatry, 165(1), 116–123. https://doi.org/10.1176/appi.ajp.2007.07010143

32.

Kessler

R. C.

Berglund

Demler

Jin

Merikangas

K. R.

Walters

E. E.

(2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62(6), 593–602. https://doi.org/10.1001/archpsyc.62.6.593

33.

Klawohn

Hajcak

Amir

Kathmann

Riesel

(2020). Application of attentional bias modification training to modulate hyperactive error-monitoring in OCD. International Journal of Psychophysiology, 156, 79–86. https://doi.org/10.1016/j.ijpsycho.2020.07.005

34.

Klein

R. G.

(1991). Parent–child agreement in clinical assessment of anxiety and other psychopathology: A review. Journal of Anxiety Disorders, 5, 187–198.

35.

Kujawa

Weinberg

Bunford

Fitzgerald

K. D.

Hanna

G. L.

Monk

C. S.

Kennedy

A. E.

Klumpp

Hajcak

Phan

K. L.

(2016). Error-related brain activity in youth and young adults before and after treatment for generalized or social anxiety disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 71, 162–168. https://doi.org/10.1016/j.pnpbp.2016.07.010

36.

Ladouceur

C. D.

Dahl

R. E.

Birmaher

Axelson

D. A.

Ryan

N. D.

(2006). Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 47(10), 1073–1082. https://doi.org/10.1111/j.1469-7610.2006.01654.x

37.

Ladouceur

C. D.

Tan

P. Z.

Sharma

Bylsma

L. M.

Silk

J. S.

Siegle

G. J.

Forbes

E. E.

McMakin

D. L.

Dahl

R. E.

Kendall

P. C.

Mannarino

Ryan

N. D.

(2018). Error-related brain activity in pediatric anxiety disorders remains elevated following individual therapy: A randomized clinical trial. Journal of Child Psychology and Psychiatry, 59(11), 1152–1161. https://doi.org/10.1111/jcpp.12900

38.

Lahat

Lamm

Chronis-Tuscano

Pine

D. S.

Henderson

H. A.

Fox

N. A.

(2014). Early behavioral inhibition and increased error monitoring predict later social phobia symptoms in childhood. Journal of the American Academy of Child and Adolescent Psychiatry, 53(4), 447–455. https://doi.org/10.1016/j.jaac.2013.12.019

39.

Little

Yau

(1996). Intent-to-treat analysis for longitudinal studies with drop-outs. Biometrics, 52(4), 1324–1333.

40.

Lonigan

C. J.

Vasey

M. W.

Phillips

B. M.

Hazen

R. A.

(2004). Temperament, anxiety, and the processing of threat-relevant stimuli. Journal of Clinical Child and Adolescent Psychology, 33(1), 8–20. https://doi.org/10.1207/S15374424JCCP3301_2

41.

Lowther

Newman

(2014). Attention bias modification (ABM) as a treatment for child and adolescent anxiety: A systematic review. Journal of Affective Disorders, 168, 125–135. https://doi.org/10.1016/j.jad.2014.06.051

42.

MacLeod

Rutherford

Campbell

Ebsworthy

Holker

(2002). Selective attention and emotional vulnerability: Assessing the causal basis of their association through the experimental manipulation of attentional bias. Journal of Abnormal Psychology, 111, 107–123. https://doi.org/10.1037/0021-843X.111.1.107

43.

Mancebo

M. C.

Boisseau

C. L.

Garnaat

S. L.

Eisen

J. L.

Greenberg

B. D.

Sibrava

N. J.

Stout

R. L.

Rasmussen

S. A.

(2014). Long-term course of pediatric obsessive-compulsive disorder: 3 years of prospective follow-up. Comprehensive Psychiatry, 55(7), 1498–1504. https://doi.org/10.1016/j.comppsych.2014.04.010

44.

Martinelli

Grüll

Baum

(2022). Attention and interpretation cognitive bias change: A systematic review and meta-analysis of bias modification paradigms. Behaviour Research and Therapy, 157, Article 104180. https://doi.org/10.1016/j.brat.2022.104180

45.

Mathews

MacLeod

(2005). Cognitive vulnerability to emotional disorders. Annual Review of Clinical Psychology, 1, 167–195. https://doi.org/10.1146/annurev.clinpsy.1.102803.143916

46.

McDermott

J. M.

Perez-Edgar

Henderson

H. A.

Chronis-Tuscano

Pine

D. S.

Fox

N. A.

(2009). A history of childhood behavioral inhibition and enhanced response monitoring in adolescence are linked to clinical anxiety. Biological Psychiatry, 65(5), 445–448. https://doi.org/10.1016/j.biopsych.2008.10.043

47.

Meyer

(2017). A biomarker of anxiety in children and adolescents: A review focusing on the error-related negativity (ERN) and anxiety across development. Developmental Cognitive Neuroscience, 27, 58–68. https://doi.org/10.1016/j.dcn.2017.08.001

48.

Meyer

Gibby

Wissemann

Klawohn

Hajcak

Schmidt

N. B.

(2020). A brief, computerized intervention targeting error sensitivity reduces the error-related negativity. Cognitive, Affective & Behavioral Neuroscience, 20(1), 172–180. https://doi.org/10.3758/s13415-019-00760-w

49.

Meyer

Hajcak

(2019). A review examining the relationship between individual differences in the error-related negativity and cognitive control. International Journal of Psychophysiology, 144, 7–13. https://doi.org/10.1016/j.ijpsycho.2019.07.005

50.

Meyer

Hajcak

Torpey

D. C.

Kujawa

Kim

Bufferd

Carlson

Klein

D. N.

(2013). Increased error-related brain activity in six-year-old children with clinical anxiety. Journal of Abnormal Child Psychology, 41(8), 1257–1266. https://doi.org/10.1007/s10802-013-9762-8

51.

Meyer

Hajcak

Torpey-Newman

D. C.

Kujawa

Klein

D. N.

(2015). Enhanced error-related brain activity in children predicts the onset of anxiety disorders between the ages of 6 and 9. Journal of Abnormal Psychology, 124(2), 266–274. https://doi.org/10.1037/abn0000044

52.

Meyer

Mehra

Hajcak

(2021). Error-related negativity predicts increases in anxiety in a sample of clinically anxious female children and adolescents over 2 years. Journal of Psychiatry & Neuroscience, 46(4), E472–E479. https://doi.org/10.1503/jpn.200128

53.

Meyer

Nelson

Perlman

Klein

D. N.

Kotov

(2018). A neural biomarker, the error-related negativity, predicts the first onset of generalized anxiety disorder in a large sample of adolescent females. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 59(11), 1162–1170. https://doi.org/10.1111/jcpp.12922

54.

Meyer

Weinberg

Klein

D. N.

Hajcak

(2012). The development of the error related negativity (ERN) and its relationship with anxiety: Evidence from 8 to 13 year-olds. Developmental Cognitive Neuroscience, 2(1), 152–161. https://doi.org/10.1016/j.dcn

55.

Mikhael

Watson

Anderson

B. A.

Le Pelley

M. E.

(2021). You do it to yourself: Attentional capture by threat-signaling stimuli persists even when entirely counterproductive. Emotion, 21(8), 1691–1698. https://doi.org/10.1037/emo0001003

56.

Mogg

Waters

A. M.

Bradley

B. P.

(2017). Attention Bias Modification (ABM): Review of effects of multisession ABM training on anxiety and threat-related attention in high-anxious individuals. Clinical Psychological Science, 5(4), 698–717. https://doi.org/10.1177/2167702617696359

57.

Moser

J. S.

Hajcak

Simons

R. F.

(2005). The effects of fear on performance monitoring and attentional allocation. Psychophysiology, 42(3), 261–268. https://doi.org/10.1111/j.1469-8986.2005.00290.x

58.

Moser

J. S.

Moran

T. P.

Schroder

H. S.

Donnellan

M. B.

Yeung

(2013). On the relationship between anxiety and error monitoring: A meta-analysis and conceptual framework. Frontiers in Human Neuroscience, 7, Article 466. https://doi.org/10.3389/fnhum.2013.00466

59.

Muris

Merckelbach

Van Brakel

Mayer

(1999). The revised version of the screen for child anxiety related emotional disorders (SCARED-R): Further evidence for its reliability and validity. Anxiety, Stress, & Coping, 12, 411–425.

60.

Muris

Ollendick

T. H.

(2005). The role of temperament in the etiology of child psychopathology. Clinical Child and Family Psychology Review, 8(4), 271–289. https://doi.org/10.1007/s10567-005-8809-y

61.

Nelson

B. D.

Jackson

Amir

Hajcak

(2015). Single-session attention bias modification and error-related brain activity. Cognitive, Affective & Behavioral Neuroscience, 15(4), 776–786. https://doi.org/10.3758/s13415-015-0365-4

62.

Nelson

B. D.

Jackson

Amir

Hajcak

(2017). Attention bias modification reduces neural correlates of response monitoring. Biological Psychology, 129, 103–110. https://doi.org/10.1016/j.biopsycho.2017.08.059

63.

Ollendick

T. H.

White

S. W.

Richey

Kim-Spoon

Ryan

S. M.

Wieckowski

A. T.

Coffman

M. C.

Elias

Strege

M. V.

Capriola-Hall

N. N.

Smith

(2019). Attention bias modification treatment for adolescents with social anxiety disorder. Behavior Therapy, 50(1), 126–139. https://doi.org/10.1016/j.beth.2018.04.002

64.

Olvet

D. M.

Hajcak

(2008). The error-related negativity (ERN) and psychopathology: Toward an endophenotype. Clinical Psychology Review, 28(8), 1343–1354. https://doi.org/10.1016/j.cpr.2008.07.003

65.

Olvet

D. M.

Hajcak

(2009a). Reliability of error-related brain activity. Brain Research, 1284, 89–99. https://doi.org/10.1016/j.brainres.2009.05.079

66.

Olvet

D. M.

Hajcak

(2009b). The stability of error-related brain activity with increasing trials. Psychophysiology, 46(5), 957–961. https://doi.org/10.1111/j.1469-8986.2009.00848.x

67.

Pergamin-Hight

Pine

D. S.

Fox

N. A.

Bar-Haim

(2016). Attention bias modification for youth with social anxiety disorder. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 57(11), 1317–1325. https://doi.org/10.1111/jcpp.12599

68.

Pettit

J. W.

Bechor

Rey

Vasey

M. W.

Abend

Pine

D. S.

Bar-Haim

Jaccard

Silverman

W. K.

(2020). A randomized controlled trial of attention bias modification treatment in youth with treatment-resistant anxiety disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 59, 157–165.

69.

Pine

D. S.

Cohen

Gurley

Brook

(1998). The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders. Archives of General Psychiatry, 55, 56–64. https://doi.org/10.1001/archpsyc.55.1.56

70.

Posner

M. I.

(1980). Orienting of attention. The Quarterly Journal of Experimental Psychology, 32(1), 3–25. https://doi.org/10.1080/00335558008248231

71.

Posner

M. I.

Rothbart

M. K.

(2000). Developing mechanisms of self-regulation. Development and Psychopathology, 12(3), 427–441. https://doi.org/10.1017/s0954579400003096

72.

Rabinak

C. A.

Holman

Angstadt

Kennedy

A. E.

Hajcak

Phan

K. L.

(2013). Neural response to errors in combat-exposed returning veterans with and without post-traumatic stress disorder: A preliminary event-related potential study. Psychiatry Research, 213(1), 71–78. https://doi.org/10.1016/j.pscychresns.2013.01.002

73.

Riesel

Endrass

Auerbach

L. A.

Kathmann

(2015). Overactive performance monitoring as an endophenotype for obsessive-compulsive disorder: Evidence from a treatment study. The American Journal of Psychiatry, 172(7), 665–673. https://doi.org/10.1176/appi.ajp.2014.14070886

74.

Rosnow

R. L.

Rosenthal

(1996). Computing contrasts, effect sizes, and counternulls on other people’s published data: General procedures for research consumers. Psychological Methods, 1(4), 331–340. https://doi.org/10.1037/1082-989X.1.4.331

75.

Rothbart

M. K.

Ellis

L. K.

Rueda

M. R.

Posner

M. I.

(2003). Developing mechanisms of temperamental effortful control. Journal of Personality, 71(6), 1113–1143. https://doi.org/10.1111/1467-6494.7106009

76.

Runyon

Chesnut

S. R.

Burley

(2018). Screening for childhood anxiety: A meta-analysis of the screen for child anxiety related emotional disorders. Journal of Affective Disorders, 240, 220–229. https://doi.org/10.1016/j.jad.2018.07.049

77.

Sawaki

Luck

S. J.

(2010). Capture versus suppression of attention by salient singletons: Electrophysiological evidence for an automatic attend-to-me signal. Attention, Perception, & Psychophysics, 72(6), 1455–1470. https://doi.org/10.3758/APP.72.6.1455

78.

Schroder

H. S.

Moran

T. P.

Moser

J. S.

(2018). The effect of expressive writing on the error-related negativity among individuals with chronic worry. Psychophysiology, 55(2), Article 10.1111/psyp.12990. https://doi.org/10.1111/psyp.12990

79.

Shackman

A. J.

Salomons

T. V.

Slagter

H. A.

Fox

A. S.

Winter

J. J.

Davidson

R. J.

(2011). The integration of negative affect, pain and cognitive control in the cingulate cortex. Nature Reviews Neuroscience, 12, 154–167. https://doi.org/10.1038/nrn2994

80.

Sheehan

Lecrubier

Sheehan

Amorim

Janavs

Weiller

Hergueta

Baker

Dunbar

G. C.

(1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. The Journal of Clinical Psychiatry, 59(Suppl. 20), 22–33.

81.

Simons

R. F.

(2010). The way of our errors: Theme and variations. Psychophysiology, 47(1), 1–14. https://doi.org/10.1111/j.1469-8986.2009.00929.x

82.

Singer

J. D.

Willett

J. B.

(2003). Applied longitudinal data analysis: Modeling change and event occurrence. Oxford University Press. https://doi.org/10.1093/acprof:oso/9780195152968.001.0001

83.

Spielberger

C. D.

Gorsuch

R. L.

Lushene

Vagg

P. R.

Jacobs

G. A.

(1983). Manual for the state-trait anxiety inventory. Consulting Psychologists Press.

84.

Stockings

Degenhardt

Lee

Y. Y.

Mihalopoulos

Liu

Hobbs

Patton

(2015). Symptom screening scales for detecting major depressive disorder in children and adolescents: A systematic review and meta-analysis of reliability, validity and diagnostic utility. Journal of Affective Disorders, 174, 447–463. https://doi.org/10.1016/j.jad.2014.11.061

85.

Tan

P. Z.

Rozenman

Chang

S. W.

Jurgiel

Truong

H. V.

Piacentini

Loo

S. K.

(2021). The ERN as a neural index of changes in performance monitoring following attention training in pediatric obsessive-compulsive disorder. Biological Psychology, 166, Article 108206. https://doi.org/10.1016/j.biopsycho.2021.108206

86.

Taylor

C. T.

Aupperle

R. L.

Flagan

Simmons

A. N.

Amir

Stein

M. B.

Paulus

M. P.

(2014). Neural correlates of a computerized attention modification program in anxious subjects. Social Cognitive and Affective Neuroscience, 9(9), 1379–1387. https://doi.org/10.1093/scan/nst128

87.

Tingley

Yamamoto

Hirose

Keele

Imai

(2014). mediation: R package for causal mediation analysis. Journal of Statistical Software, 59(5), 1–38. https://doi.org/10.18637/jss.v059.i05

88.

Vaidyanathan

Nelson

L. D.

Patrick

C. J.

(2012). Clarifying domains of internalizing psychopathology using neurophysiology. Psychological Medicine, 42(3), 447–459. https://doi.org/10.1017/S0033291711001528

89.

Vasey

M. W.

MacLeod

(2001). Information-processing factors in childhood anxiety: A review and developmental perspective. In Vasey

M. W.

Dadds

M. R.

(Eds.), The developmental psychopathology of anxiety (pp. 253–277). Oxford University Press.

90.

Weinberg

Dieterich

Riesel

(2015). Error-related brain activity in the age of RDoC: A review of the literature. International Journal of Psychophysiology, 98(2, Pt. 2), 276–299. https://doi.org/10.1016/j.ijpsycho.2015.02.029

91.

Weinberg

Hajcak

(2011). Longer term test-retest reliability of error-related brain activity. Psychophysiology, 48(10), 1420–1425. https://doi.org/10.1111/j.1469-8986.2011.01206.x

92.

Weinberg

Klein

D. N.

Hajcak

(2012). Increased error-related brain activity distinguishes generalized anxiety disorder with and without comorbid major depressive disorder. Journal of Abnormal Psychology, 121(4), 885–896. https://doi.org/10.1037/a0028270

93.

Weinberg

Meyer

Hale-Rude

Perlman

Kotov

Klein

D. N.

Hajcak

(2016). Error-related negativity (ERN) and sustained threat: Conceptual framework and empirical evaluation in an adolescent sample. Psychophysiology, 53(3), 372–385. https://doi.org/10.1111/psyp.12538

94.

Weinberg

Olvet

D. M.

Hajcak

(2010). Increased error-related brain activity in generalized anxiety disorder. Biological Psychology, 85(3), 472–480. https://doi.org/10.1016/j.biopsycho.2010.09.011

95.

Wittchen

Lieb

Pfister

Schuster

(2000). The waxing and waning of mental disorders: Evaluating the stability of syndromes of mental disorders in the population. Comprehensive Psychiatry, 2, 122–132.

96.

Xiao

Wang

Zhang

Tang

Wang

Fan

Fromson

J. A.

(2011). Error-related negativity abnormalities in generalized anxiety disorder and obsessive-compulsive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 35(1), 265–272. https://doi.org/10.1016/j.pnpbp.2010.11.022

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