MertensJ, HerdyJR, TraxlerL, et al.Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients. Cell Stem Cell, 2021; 28(9):1533–1548.e6.
2.
MertensJ, PaquolaACM, KuM, et al.Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects. Cell Stem Cell, 2015; 17(6):705–718.
3.
PitrezPR, MonteiroLM, BorgognoO, et al.Cellular reprogramming as a tool to model human aging in a dish. Nat Commun, 2024; 15(1):1816.
4.
TraxlerL, HerdyJR, StefanoniD, et al.Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease. Cell Metab, 2022; 34(9):1248–1263.e6.
5.
TraxlerL, KarbacherL, Borgogno O, et al.An accelerated human in-vitro aging model mimics in-vivo aging and facilitates dynamic testing of anti-aging compounds. Res Sq, 2025.