CardioCel® is bovine pericardium which is subjected to a novel tissue engineering process (ADAPT®) to reduce cytotoxicity and retard calcification while maintaining strength and elasticity. We present a case where CardioCel® showed rapid degeneration and calcification after repair of an aortic valve.
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References
1.
NordmeyerSMurinPSchulzA, et al. Results of aortic valve repair using decellularized bovine pericardium in congenital surgery. Eur J Cardiothorac Surg. 2018;54(6):986-992.
2.
IonescuMITandonAPMaryDA, et al. Heart valve replacement with the Ionescu-Shiley pericardial xenograft. J Thorac Cardiovasc Surg.1977;73(1):31-42.
3.
NeethlingWMStrangeGFirthL, et al. Evaluation of a tissue-engineered bovine pericardial patch in paediatric patients with congenital cardiac anomalies: initial experience with the ADAPT-treated CardioCel® (R) patch. Interact Cardiovasc Thorac Surg. 2013;17(4):698-702.
4.
PavyCMichielonGRobertusJL, et al. Initial 2-year results of CardioCel® patch implantation in children. Interact Cardiovasc Thorac Surg. 2018;26(3):448-453.
5.
MazzitelliDNobauerCRankinJS, et al. Complete aortic valve cusp replacement in the pediatric population using tissue-engineered bovine pericardium. Ann Thorac Surg.2015;100(5):1923-1925.
6.
ChiversSCPavyCVajaR, et al. The Ozaki procedure with CardioCel® patch for children and young adults with aortic valve disease: preliminary experience - a word of caution. World J Pediatr Congenit Heart Surg.2019;10(6):724-730.