Urethral involvement of myeloma: A rare case of visible haematuria leading to a diagnosis of relapsed multiple myeloma after curative stem cell transplantation

Abstract

Extramedullary multiple myeloma involving the urinary tract is extremely rare. We report an unusual case of visible haematuria in a 45-year-old male who had a stem cell transplant for multiple myeloma 18 months previously. Cysto-urethroscopy revealed a mid-urethral lesion that was then fully excised by endoscopic resection. Histology confirmed malignant plasma cell infiltrate with subsequent staging and skeletal biopsy of a rib lesion confirming relapse of multiple myeloma. We believe this is the first case of urethral involvement to reveal a relapse of multiple myeloma after autologous stem cell transplant.

Keywords

Urethral tumour urinary tract myeloma extramedullary myeloma haematuria malignancy

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