Are statins back for patients on hemodialysis?

Thomas B Matsushita K Abate KH , et al. Global cardiovascular and renal outcomes of reduced GFR. J Am Soc Nephrol 2017; 28: 2167–2179.

Kendrick J Chonchol MB. Nontraditional risk factors for cardiovascular disease in patients with chronic kidney disease. Nat Clin Pract Nephrol 2008; 4: 672–681.

Kwan BCH Kronenberg F Beddhu S , et al. Lipoprotein metabolism and lipid management in chronic kidney disease. J Am Soc Nephrol 2007; 18: 1246–61.

Wanner C Krane V März W , et al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 2005; 353: 238–248.

Fellström BC Jardine AG Schmieder RE , et al. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med 2009; 360: 1395–1407.

Baigent C Landray MJ Reith C , et al. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): A randomised placebo-controlled trial. Lancet 2011; 377: 2181–2192.

März W Genser B Drechsler C , et al. Atorvastatin and low-density lipoprotein cholesterol in type 2 diabetes mellitus patients on hemodialysis. Clin J Am Soc Nephrol 2011; 6: 1316–1325.

Genser B, Wanner C and März W. A scoring system for predicting individual treatment effects of statins in type 2 diabetes patients on haemodialysis. Eur J Prev Cardiol 2020. Epub ahead of print, DOI: 10.1177/2047487320905721.

Mach F Baigent C Catapano AL , et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk. Eur Heart J 2020; 41: 111–188.

Wanner C Tonelli M and the Kidney Disease: Improving Global Outcomes Lipid Guideline Development Work Group Members. KDIGO clinical practice guideline for lipid management in CKD: Summary of recommendation statements and clinical approach to the patient. Kidney Int 2014; 85: 1303–1309.

Streja E Gosmanova EO Molnar MZ , et al. Association of continuation of statin therapy initiated before transition to chronic dialysis therapy with mortality after dialysis initiation. JAMA Netw Open 2018; 1: e182311.