CatapanoALGrahamIDe BackerGet al.2016 ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS). Eur Heart J2016; 37: 2999–3058.
2.
ReinerŽ. Statins in the primary prevention of cardiovascular disease. Nat Rev Cardiol2013; 10: 453–464.
3.
PećinIHartgersMLHovinghGKet al.Prevention of cardiovascular disease in patients with familial hypercholesterolaemia: the role of PCSK9 inhibitors. Eur J Prev Cardiol2017; 24: 1383–1401.
4.
ReinerŽ. PCSK9 inhibitors-past, present and future. Expert Opin Drug Metab Toxicol2015; 11: 1517–1521.
5.
ReinerŽLaufsUCosentinoFet al.The year in cardiology 2018: prevention. Eur Heart J2019; 40: 336–344.
MacchiCBanachMCorsiniAet al.Changes in circulating PCSK9 levels – experimental and clinical approaches with lipid lowering agents. Eur J Prevent Cardiol. 2019; 26: 928–929.
8.
WelderGZinehIPacanowskiMAet al.High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol. J Lipid Res2010; 51: 2714–2721.
9.
VlachopoulosCTerentes-PrintziosDGeorgiopoulosGet al.Prediction of cardiovascular events with levels of proprotein convertase subtilisin/kexin type 9: a systematic review and meta-analysis. Atherosclerosis2016; 252: 50–60.
10.
El KhouryPRousselRFumeronFet al.Plasma proprotein-convertase-subtilisin/kexin type 9 (PCSK9) and cardiovascular events in type 2 diabetes. Diabetes Obes Metab2018; 20: 943–953.