ChenRModyPSGuptaAet al.Most important outcomes research papers on body weight, obesity and cardiovascular outcomes. Circ Cardiovasc Qual Outcomes2013; 6: e48–e56.
2.
DoresHde Araujo GoncalvesPCarvalhoMSet al.Body mass index as a predictor of the presence but not the severity of coronary artery disease evaluated by cardiac computed tomography. Eur J Prev Cardiol2014; 21: 1387–1393.
3.
RoeverLSResendeESDinizALet al.Abdominal obesity and association with atherosclerosis risk factors: The Uberlandia Heart Study. Medicine (Baltimore)2016; 95: e1357–e1357.
4.
ReederBASenthilselvanADespresJPet al.The association of cardiovascular disease risk factors with abdominal obesity in Canada. Canadian Heart Health Surveys Research Group. CMAJ1997; 157(Suppl 1): S39–S45.
5.
FranksPWHansonRLKnowlerWCet al.Childhood obesity, other cardiovascular risk factors, and premature death. N Engl J Med2010; 362: 485–493.
6.
BalkauBDeanfieldJEDespresJPet al.International Day for the Evaluation of Abdominal Obesity (IDEA): A study of waist circumference, cardiovascular disease, and diabetes mellitus in 168,000 primary care patients in 63 countries. Circulation2007; 116: 1942–1951.
7.
FranssensBTNathoeHMLeinerTet al.Relation between cardiovascular disease risk factors and epicardial adipose tissue density on cardiac computed tomography in patients at high risk of cardiovascular events. Eur J Prev Cardiol2017; 24: 660–670.
RosenquistKJPedleyAMassaroJMet al.Visceral and subcutaneous fat quality and cardiometabolic risk. JACC Cardiovasc Imaging2013; 6: 762–771.
10.
HotamisligilGSShargillNSSpiegelmanBM. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science1993; 259: 87–91.
11.
WeisbergSPMcCannDDesaiMet al.Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest2003; 112: 1796–1808.
12.
XuHBarnesGTYangQet al.Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest2003; 112: 1821–1830.
13.
CuratCAMiranvilleASengenesCet al.From blood monocytes to adipose tissue-resident macrophages: Induction of diapedesis by human mature adipocytes. Diabetes2004; 53: 1285–1292.
14.
SicaAMantovaniA. Macrophage plasticity and polarization: In vivo veritas. J Clin Invest2012; 122: 787–795.
15.
ZhouYYuXChenHet al.Leptin deficiency shifts mast cells toward anti-inflammatory actions and protects mice from obesity and diabetes by polarizing M2 macrophages. Cell Metab2015; 22: 1045–1058.
16.
LohmannCSchaferNvon LukowiczTet al.Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets. Atherosclerosis2009; 207: 360–367.
PolsTWNomuraMHarachTet al.TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading. Cell Metab2011; 14: 747–757.
20.
Lesna IK, Petras M, Cejkova S, et al. Cardiovascular disease predictors and adipose tissue macrophage polarization: Is there a link? Eur J Prev Cardiol. 2018; 25: 328–334.
21.
BeaFBlessingEShelleyMIet al.Simvastatin inhibits expression of tissue factor in advanced atherosclerotic lesions of apolipoprotein E deficient mice independently of lipid lowering: Potential role of simvastatin-mediated inhibition of Egr-1 expression and activation. Atherosclerosis2003; 167: 187–194.
22.
LeungPOWangSHLuSHet al.Simvastatin inhibits pro-inflammatory mediators through induction of heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW264.7 macrophages. Toxicol Lett2011; 207: 159–166.
23.
ShyuKGChuaSKWangBWet al.Mechanism of inhibitory effect of atorvastatin on resistin expression induced by tumor necrosis factor-alpha in macrophages. J Biomed Sci2009; 16: 50–50.
24.
TuomistoTTLumivuoriHKansanenEet al.Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2. Cardiovasc Res2008; 78: 175–184.
25.
FoxCSMassaroJMHoffmannUet al.Abdominal visceral and subcutaneous adipose tissue compartments: Association with metabolic risk factors in the Framingham Heart Study. Circulation2007; 116: 39–48.
26.
YingWRiopelMBandyopadhyayGet al.Adipose tissue macrophage-derived exosomal miRNAs can modulate in vivo and in vitro insulin sensitivity. Cell2017; 171: 372–384e12.
