Neurohormonal modulation for treatment of cardiac involvement in dystrophinopathies and mitochondrial disease

Abstract

Get full access to this article

View all access options for this article.

References

Aimo A, Giannoni A, Castiglione V, et al. Neurohormonal modulation for treatment of cardiac involvement in dystrophinopathies and mitochondrial disease. Eur J Prevent Cardiol. 2017; 24: 1718–1724.

Raman

Hor

Mazur

et al.

Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: results of a two-year open-label extension trial. Orphanet J Rare Dis 2017; 12: 39–39.

Finsterer

. Left ventricular non-compaction and its cardiac and neurologic implications. Heart Fail Rev 2010; 15: 589–603.

Psotka

Teerlink

. Ivabradine: role in the chronic heart failure armamentarium. Circulation 2016; 133: 2066–2075.

Doehner

Frenneaux

Anker

. Metabolic impairment in heart failure: the myocardial and systemic perspective. J Am Coll Cardiol 2014; 64: 1388–1400.

Coats

Clark

Piepoli

et al.

Symptoms and quality of life in heart failure: the muscle hypothesis. Br Heart J 1994; 72: S36–S39.

Piepoli

Coats

. The ‘skeletal muscle hypothesis in heart failure’ revised. Eur Heart J 2013; 34: 486–488.

Piepoli

Crisafulli

. Pathophysiology of human heart failure: importance of skeletal muscle myopathy and reflexes. Exp Physiol 2014; 99: 609–615.

Piepoli

Clark

Volterrani

et al.

Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure: effects of physical training. Circulation 1996; 93: 940–952.

10.

Smith

Downey

Williamson

et al.

Autonomic dysfunction in muscular dystrophy: a theoretical framework for muscle reflex involvement. Front Physiol 2014; 5: 47–47.

11.

Bates

Newman

Jakovljevic

et al.

Defining cardiac adaptations and safety of endurance training in patients with m.3243A>G-related mitochondrial disease. Int J Cardiol 2013; 168: 3599–3608.

12.

Taivassalo

Jensen

Kennaway

et al.

The spectrum of exercise tolerance in mitochondrial myopathies: a study of 40 patients. Brain 2003; 126: 413–423.

13.

Aimo

Giannoni

Piepoli

et al.

Myocardial damage in a mitochondrial myopathy patient with increased ergoreceptor sensitivity and sympatho-vagal imbalance. Int J Cardiol 2014; 176: 1396–1398.

14.

Giannoni A, Aimo A, Mancuso M, et al. Autonomic, functional, skeletal muscle, and cardiac abnormalities are associated with increased ergoreflex sensitivity in mitochondrial disease. Eur J Heart Fail. Epub ahead of print 24 February 2017. DOI: 10.1002/ejhf.782.