Balancing the evidence on the cardiovascular determinants of oxygen uptake improvement after endurance training in the elderly: What are the next steps?
Restricted accessEditorialFirst published online May, 2016
Balancing the evidence on the cardiovascular determinants of oxygen uptake improvement after endurance training in the elderly: What are the next steps?
MonteroDDíaz-CañestroC. Endurance training and maximal oxygen consumption with ageing: Role of maximal cardiac output and oxygen extraction. Eur J Prev Cardiol2015. 2016; 23: 733–743.
2.
MonteroDDiaz-CañestroCLundbyC. Endurance training and VO2max: Role of maximal cardiac output and oxygen extraction. Med Sci Sports Exerc2015; 47: 2024–2033.
3.
AndersenPSaltinB. Maximal perfusion of skeletal muscle in man. J Physiol1985; 366: 233–249.
4.
RichardsonRSGrassiBGavinTP. Evidence of O2 supply-dependent VO2max in the exercise-trained human quadriceps. J Appl Physiol1999; 86: 1048–1053.
KlausenKSecherNHClausenJP. Central and regional circulatory adaptations to one-leg training. J Appl Physiol Respir Environ Exerc Physiol1982; 52: 976–983.
7.
RudBFossOKrustrupP. One-legged endurance training: Leg blood flow and oxygen extraction during cycling exercise. Acta Physiol (Oxf)2012; 205: 177–185.
8.
EspositoFMathieu-CostelloOShabetaiR. Limited maximal exercise capacity in patients with chronic heart failure: Partitioning the contributors. J Am Coll Cardiol2010; 55: 1945–1954.
9.
VellaCARobergsRA. A review of the stroke volume response to upright exercise in healthy subjects. Br J Sports Med2005; 39: 190–195.
10.
BorlaugBAMelenovskyVRussellSD. Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. Circulation2006; 114: 2138–2147.
11.
PhanTTShivuGNAbozguiaK. Impaired heart rate recovery and chronotropic incompetence in patients with heart failure with preserved ejection fraction. Circ Heart Fail2010; 3: 29–34.
12.
GuazziM. Training the left ventricle with preserved ejection fraction or cardiorespiratory fitness? Rocking the boat. Circ Heart Fail2015; 8: 5–7.
13.
BhellaPSPrasadAHeinickeK. Abnormal haemodynamic response to exercise in heart failure with preserved ejection fraction. Eur J Heart Fail2011; 13: 1296–1304.
14.
HaykowskyMJBrubakerPHJohnJM. Determinants of exercise intolerance in elderly heart failure patients with preserved ejection fraction. J Am Coll Cardiol2011; 58: 265–274.
15.
AbudiabMMRedfieldMMMelenovskyV. Cardiac output response to exercise in relation to metabolic demand in heart failure with preserved ejection fraction. Eur J Heart Fail2013; 15: 776–785.
16.
ShimiaieJSherezJAviramG. Determinants of effort intolerance in patients with heart failure: Combined echocardiography and cardiopulmonary stress protocol. JACC Heart Fail2015; 3: 803–814.
17.
DhakalBPMalhotraRMurphyRM. Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: The role of abnormal peripheral oxygen extraction. Circ Heart Fail2015; 8: 286–294.
18.
SantosMOpotowskyARShahAM. Central cardiac limit to aerobic capacity in patients with exertional pulmonary venous hypertension: Implications for heart failure with preserved ejection fraction. Circ Heart Fail2015; 8: 278–285.
