During exercise, ventilation for a given work rate is increased in pulmonary hypertension. In the present editorial a new look at the ventilatory behaviour, which may change the common approach to VE/VCO2 relationship analysis, is presented.
Get full access to this article
View all access options for this article.
References
1.
Wasserman K, Hansen JE, Sue DY, et al. Physiology of exercise. In: (eds) Principles of exercise testing and interpretation, 5th ed. Philadelphia, USA: Lippincott Williams & Wilkins–Wolters Kluwer Health, 2012, chapter 2, pp.9–61.
2.
AgostoniPValentiniMMagriD. Disappearance of isocapnic buffering period during increasing work rate exercise at high altitude. Eur J Cardiovasc Prev Rehabil2008; 15: 354–358.
3.
AgostoniPContiniMCattadoriG. Lung function with carvedilol and bisoprolol in chronic heart failure: is beta selectivity relevant?Eur J Heart Fail2007; 9: 827–833.
4.
ArenaRMyersJAbellaJ. Development of a ventilatory classification system in patients with heart failure. Circulation2007; 115: 2410–2417.
5.
GittAKWassermanKKilkowskiC. Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early death. Circulation2002; 106: 3079–3084.
6.
YasunobuYOudizRJSunXG. End-tidal PCO2 abnormality and exercise limitation in patients with primary pulmonary hypertension. Chest2005; 127: 1637–1646.
7.
GroepenhoffHVonk-NoordegraafABoonstraA. Exercise testing to estimate survival in pulmonary hypertension. Med Sci Sports Exerc2008; 40: 1725–1732.
8.
SunXGHansenJEGaratacheaN. Ventilatory efficiency during exercise in healthy subjects. Am J Respir Crit Care Med2002; 166: 1443–1448.
9.
TabetJYBeauvaisFThabutG. A critical appraisal of the prognostic value of the VE/VCO2 slope in chronic heart failure. Eur J Cardiovasc Prev Rehabil2003; 10: 267–272.
10.
FerreiraEMVOta-ArakakiJRamosR. Optimizing th evaluation of excessive exercise ventilation for prognosis assessment in pulmonary arterial hypertension. Eur J Prev Cardiol2013. (Epub ahead of print).
11.
AgostoniPGButlerJCardiac evaluation. In: MurrayJFNadelJA (eds). Textbook of respiratory disease, 2nd edn. Philadelphia: WB Saunders, 1994, pp. 943–962.
