Abstract
Degradable materials based on poly(α-angelica lactone-co-∊-caprolactone) (PAL-co-PCL) copolymers were successfully synthesized via ring-opening polymerization (ROP) of α-angelica lactone (AL) and ∊-caprolactone (CL). The chemical structures of the PAL-co-PCL were confirmed by 1H NMR and FT-IR measurements. The crystallization behaviour of copolymers was analyzed by XRD patterns, the thermal properties were investigated by DSC and TGA curves. The degradation rate of PAL-co-PCL could be controlled through adjusting the ratio of PAL to PCL in the copolymer as well as the pH values of media.
Get full access to this article
View all access options for this article.
References
1.
Wei X.W.
,
Gong C.Y.
,
Gou M.L.
,
Fu S.Z.
,
Guo Q.F.
,
Shi S.
,
Luo F.
,
Guo G.
,
Qiu L.Y.
, and
Qian Z.Y.
, Int. J. Pharm. , 381 , 2009 , 1 –18 .
2.
Park E.K.
,
Kim S.Y.
,
Lee S.B.
, and
Lee Y.M.
, J. Controlled Release , 109 , 2005 , 158 –168 .
3.
Shi S.
,
Fan M.
,
Wang X.H.
,
Zhao C.J.
,
Wang Y.J.
,
Luo F.
, and
Zhao X.
, and
Qian Z.Y.
, J. Phys. Chem. C. , 114 , 2010 , 21315 –21321 .
4.
Andrew S.
, and
Allen C.
, Biomacromolecules , 11 , 2010 , 1273 –1280 .
5.
Brostrom J.
,
Boss A.
, and
Chronakis I.S.
, Biomacromolecules , 5 , 2004 , 1124 –1134 .
6.
Gong C.Y.
,
Shi S.
,
Dong P.W.
,
Kan B.
,
Gou M.L.
,
Li X.H.
,
Luo F.
,
Zhao X.
, and
Wei Y.Q.
, Int. J. Pharm. , 35 , 2009 , 89 –99 .
7.
Lee J.W.
,
Hua F.J.
, and
Lee D.S.
, J. Controlled Release , 73 , 2001 , 315 –327 .
8.
Miao Z.M.
,
Cheng S.X.
,
Zhang X.Z.
, and
Zuo R.X.
, Biomacromolecules , 7 , 2006 , 2020 –2026 .
9.
Wang F.
,
Bronich T.K.
,
Kabanov A.V.
, and
Roovers R.D.
, Bioconjugate Chem. , 16 , 2005 , 397 –405 .
10.
Lee J.H.
,
Kopeckova P.
,
Kopecek J.
, and
Andrade J.D.
, Biomaterials , 11 , 1990 , 455 –464 .
11.
Dietmar W.
, and
Hutmacher
, Biomaterials , 21 , 2000 , 2529 –2534 .
12.
Ciardelli G.
,
Chiono V.
,
Vozzi G.
,
Pracella M.
,
Ahluwalia A.
,
Barbani N.
,
Cristallini C.
, and
Giusti P.
, Biomacromolecules , 6 , 2005 , 1961 –1976 .
13.
Mattanavee W.
,
Suwantong O.
,
Puthong S.
,
Bunaprasert T.
,
Voravee P.
, and
Supaphol P.
, ACS Appl. Mater. Interfaces , 1 , 2009 , 1076 –1085 .
14.
Curtin S.
,
Trinh P.
,
Bryant S.
, and
Ratner B.
, Biomacromolecules , 9 , 2008 , 3370 –3377 .
15.
Tiaw K.S.
,
Teoh S.H.
,
Chen R.
, and
Hong M.H.
, Biomacromolecules , 8 , 2007 , 807 –816 .
16.
Bae S.J.
,
Suh J.M.
,
Sohn Y.S.
,
Bae Y.H.
,
Kim S.W.
, and
Jeong B.
, Macromolecules , 38 , 2005 , 5260 –5265 .
17.
Xiong M.P.
,
Yaez J.A.
,
Remsberg C.M.
,
Ohgami Y.
,
Kwon G.S.
,
Davies N.M.
, and
Forrest M.L.
, J. Controlled Release , 109 , 2005 , 158 –168 .
18.
Ren J.M.
,
Blencowe A.
, and
Qiao G.G.
, ACS Macro Lett. , 1 , 2012 , 681 –686 .
19.
Du J.Z.
, and
Chen Y.M.
, Macromolecules , 37 , 2004 , 3588 –3594 .
20.
Lee H.
,
Matajaszewski K.
,
Su S.Y.
, and
Sheiko S.S.
, Macromolecules , 41 , 2008 , 6073 –6080 .
21.
Målberg S.
,
Hönglund A.
, and
Albertson A.C.
, Biomacromolecules , 12 , 2011 , 2382 –2388 .
22.
Fiore G.L.
, and
Fraser C.L.
, Macromolecules , 41 , 2008 , 7892 –7897 .
23.
Hua C.
,
Dong C.M.
, and
Wei Y.
, Biomacromolecules , 10 , 2009 , 1140 –1148 .
24.
Garg S.M.
,
Xiong X.B.
, and
Lu C.H.
, Macromolecules , 44 , 2011 , 2058 –2066 .
25.
Khanna K.
,
Varshney S.
, and
KaKKar A.
, Macromolecules , 43 , 2010 , 5688 –5698 .
26.
Yao K.J.
,
Wang J.F.
,
Zheng W.J.
,
Lee J.S.
,
Wu C.P.
,
Chu F.X.
,
He X.M.
, and
Tang C.B.
, Biomacromolecules , 12 , 2011 , 2171 –2177 .
27.
Chen J.C.
,
Liu M.Z.
,
Gong H.H.
,
Huang Y.J.
, and
Chen C.
, J. Phys. Chem. B , 115 , 2011 , 14947 –14955 .
28.
Persenaire O.
,
Alexandre M.
,
Degee P.
, and
Dubois P.
, Biomacromolecules , 2 , 2001 , 288 –294 .
29.
Chen T.
,
Deng T.
, and
Hou X.
, Fine Chem. , 26 , 2009 , 885 –888 .
30.
Potvin J.
,
Sorlien E.
,
Hegner J.
,
DeBoef B.
, and
Lucht B.
, Tetrahedron Lett. , 52 , 2011 , 5891 –5893 .
31.
Chen T.
,
Qin Z.F.
,
Qi Y.Q.
,
Deng T.S.
,
Ge X.J.
,
Wang J.G.
, and
Hou X.L.
, Polym. Chem. , 2 , 2011 , 1190 –1194 .
32.
Lee B.S.
,
Chun B.C.
,
Chung Y.C.
,
Sul K.I.
, and
Cho J.W.
, Macromolecules , 34 , 2001 , 6431 –6437 .
33.
Khan J.H.
,
Schue F.
, and
George G.A.
, Polym. Int. , 58 , 2009 , 296 –301 .
34.
Labet M.
, and
Thielemans W.
, Chem. Soc. Rev. , 38 , 2009 , 3484 –3504 .
35.
Nojima S.
,
Hashizume K.
,
Rohadi A.
, and
Sasaki S.
, Polymer , 38 , 1997 , 2711 –2718 .
36.
Yuan W.Z.
,
Yuan J.Y.
,
Zhang F.B.
, and
Xie X.M.
, Biomacromolecules , 8 , 2007 , 1101 –1108 .