We assessed the value of 1HMRS in the diagnosis of astrocytomas and glioblastomas compared with stereotaxic biopsy. 1HMRS is an alternative non-invasive diagnostic tool to predict the presence of malignant gliomas.
CarpinelliGCarapellaCM: Differentiation of glioblastoma multiforme from astrocytomas by in vitro 1H MRS analysis of human brain tumors. Anticancer Res16: 1559–1564, 1996.
2.
BhakooKKLandH: Phosphorylcholine: A putative marker of cancer. Differential regulation of choline metabolites during oncogenic transformation. Proc Soc Mangn Reson Med6: 69, 1996.
3.
KueselACDonnellySM: Mobile lipids and metabolic heterogeneity of brain tumors as detectable by ex vivo 1HMR spectroscopy. NMR Biomed7: 172–180, 1994.
4.
KueselACSutherlandGR: 1HMR spectroscopy of high grade astrocytomas: Mobile lipid accumulation in necrotic tissue. NMR Biomed7: 149–155, 1994.