The analysis of functional magnetic resonance imaging (fMRI) time-series data can provide information on task-related activities, functional/effective connectivity among regions and the influences of behavioral/physiologic states on connectivity. This paper illustrates the importance of the neurobiological constraints involved in using statistical parametric mapping (SPM) through Matlab simulation and thus helping the radiologist to interpret the results better. This paper also presents the results and inferences from neuroimaging data of the lip movement experiment using statistical parametric mapping (SPM). The results match with the sensory/motor activation atlas by Penfield and Rasmussen (1950).
FristonKJFrithCDTurnerR: Characterizing evoked hemodynamics with fMRI. NeuroImage2: 157–165, 1995.
7.
FristonKJUngerleiderLGJezzardP: Characterizing modulatory interactions between V1 and V2 in human cortex with fMRI. Hum. Brain Mapp. 2: 211–224, 1995.
8.
FristonKJWilliamsSHowardR: Movement related effects in fMRI time series. Mag. Res. Med.35: 346–355, 1996.
9.
GerardinELehericySPochonJB: Foot, Hand, Face and Eye Representation in the Human Stratum. Cerebral cortex13: 162–169, 2003.
10.
KoelschSFritzTSchulzeK: Adults and children processing music: An fMRI study. NeuroImage25: 1068–1076, 2005.
11.
MroczIKarniAHautS: fMRI of triggerable aurae in musicogenic epilepsy. Neurology60: 705–709, 2003.
12.
PenfieldWRasmussenT: The cerebral cortex of man. New York: Macmillan1950.
13.
SadatoNOkadaTHondaM: Cross-model inter-gartion and plastic changes revealed by lip movement, random-dot motion and sign languages in the hearing and deaf. Cerebral Cortex15: 1113–1122, 2005.
14.
TalairachJTournouxP: Co-planar stereotaxic atlas of the human brain. New York, Thieme1998.
15.
fMRI Brain Mapping Paradigms: Task Requirements and Recommendations — White Paper. Neurognostics, Inc.2006: 1–9.
