Rapid recurrent brain metastases are reported in a 51-year-old farmer. He did not receive post-operative whole-brain radiotherapy (WBRT) after complete resection of one single cerebellar tumor that was subsequently confirmed to be a metastasis from lung squamous cell carcinoma. The mechanisms of such a rapid relapse are discussed together with the roles of adjuvant WBRT.
SoffiettiRRudaRMutaniR: Management of brain metastases. J Neurol249: 1357–1369, 2002.
2.
CoxJDYesnerR: Adenocarcinoma of the lung/recent results from VA Lung Group. Am Rev Resp Dis120: 1025–1029, 1979.
3.
SchellingerPDMeinckHMThronA: Diagnostic accuracy of MRI compared to CT in patients with brain metastases. J Neurooncol44: 275–281, 1999.
4.
SzeGMilanoEJohnsonC: Detection of brain metastases: Comparison of contrast-enhanced MR with unenhanced MR and unenhanced CT. Am J Neuroradiol11: 785–791, 1990.
MintzACairncrossJG: Treatment of a single brain metastasis. The role of radiation following surgical resection. JAMA280: 1527–1529, 1998.
7.
PatchellRATibbsPARegineWE: Postoperative radiotherapy in the treatment of single metastases to the brain. JAMA280: 1485–1489, 1998.
8.
SchackertG: Surgery of brain metastases-pro and contra. Onkologie25: 480–481, 2002.
9.
SchiffD: Single brain metastasis. Curr Treat Options Neurol3: 89–99, 2001.
10.
YuhWTTaliETNguyenHD: The effect of contrast dose, imaging time, and lesion size in the MR detection of intracerebral metastasis. Am J Neuroradiol16: 373–380, 1995.
11.
Peretti-VitonPTaiebDVitonJM: Contrast-enhanced magnetization transfer MRI in metastatic lesions of the brain. Neuroradiology40: 783–787, 1998.
12.
ArbitEWronskiMBurtM: The treatment of patients with recurrent brain metastases: A retrospective analysis of 109 patients with nonsmall cell lung cancer. Cancer76: 765–773, 1995.