Abstract
The objective of this study was to compare the images obtained with a new post-processing technique with conventional Inversion Recovery (IR) sequences both on healthy volunteers and on patients with neuronal migration disorders.
The post-processing images were obtained by means of Proton Density and T2-weighted images digital addition and then the resulting images were subtracted to T1-weighted ones. The images obtained had high white/gray matter contrast resolution and were compared to conventional IR scans. Ten healthy volunteers and nine patients with neuronal migration disorders were studied. Both visual comparison and contrast to noise ratio (C/N R) evaluation were carried out, the latter with statistical methods. The visual features of the two kinds of images was the same both on healthy volunteers and on patients, whereas in the post-processed images the C/N R was statistically higher than that of conventional IR.
In conclusion our new technique is a useful tool for investigation of cerebral cortex diseases (i.e. neuronal migration disorders).
Get full access to this article
View all access options for this article.