CharalambousCSwobodaSMDickJPerlTLipsettPA. Risk factors and clinical impact of central line infections in the surgical intensive care unit. Arch Surg. 1998;133:1241-1246.
2.
NagashimaGKikuchiTTsuyuzakiH. To reduce catheter-related bloodstream infections: is the subclavian route better than the jugular route for central venous catheterization?J Infect Chemother. 2006;12:363-365.
3.
LeMasterCHSchuurJDPandyaD. Infection and natural history of emergency department-placed central venous catheters. Ann Emerg Med. 2010;56:492-497.
4.
Castellanos-OrtegaASuberviolaBGarcia-AstudilloLA. Impact of the Surviving Sepsis Campaign protocols on hospital length of stay and mortality in septic shock patients: results of a three-year follow-up quasi-experimental study. Crit Care Med. 2010;38:1036-1043.
5.
RiversE. Mixed vs central venous oxygen saturation may be not numerically equal, but both are still clinically useful. Chest. 2006;129:507-508.
6.
RiversEP. Early goal-directed therapy in severe sepsis and septic shock: converting science to reality. Chest. 2006;129:217-218.
7.
JonesAEYiannibasVJohnsonCKlineJA. Emergency department hypotension predicts sudden unexpected in-hospital mortality: a prospective cohort study. Chest. 2006;130:941-946.
8.
MarchickMRKlineJAJonesAE. The significance of non-sustained hypotension in emergency department patients with sepsis. Intensive Care Med. 2009;35:1261-1264.
9.
PoezeMRamsayGGerlachHRubulottaFLevyM. An international sepsis survey: a study of doctors’ knowledge and perception about sepsis. Crit Care. 2004;8:R409-R413.
10.
KingJE. Sepsis in critical care. Crit Care Nurs Clin North Am. 2007;19:77-86.
11.
KimCSSpahlingerDAKinJMCoffeyRJBilliJE. Implementation of lean thinking: one health system’s journey. Jt Comm J Qual Patient Saf. 2009;35:406-413.
12.
NgDVailGThomasSSchmidtN. Applying the Lean principles of the Toyota Production System to reduce wait times in the emergency department. CJEM. 2010;12:50-57.
13.
PuskarichMATrzeciakSShapiroNI; Emergency Medicine Shock Research Network (EMSHOCKNET). Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol. Crit Care Med. 2011;39:2066-2071.
14.
PhuaJNgerngWJLimTK. The impact of a delay in intensive care unit admission for community-acquired pneumonia. Eur Respir J. 2010;36:826-833.
15.
BayleyMDSchwartzJSShoferFS. The financial burden of emergency department congestion and hospital crowding for chest pain patients awaiting admission. Ann Emerg Med. 2005;45:110-117.
16.
GraffLGClarkSRadfordMJ. Critical care by emergency physicians in American and English hospitals. Arch Emerg Med. 1993;10:145-154.
17.
RezendeESilvaJMJrIsolaAMCamposEVAmendolaCPAlmeidaSL. Epidemiology of severe sepsis in the emergency department and difficulties in the initial assistance. Clinics (Sao Paulo). 2008;63:457-464.
18.
HuangDTClermontGDremsizovTTAngusDC. Implementation of early goal-directed therapy for severe sepsis and septic shock: a decision analysis. Crit Care Med. 2007;35:2090-2100.
19.
CroleyWCRothenbergDM. Education of trainees in the intensive care unit. Crit Care Med. 2007;35(2 suppl):S117-S121.
20.
JardenRJQuirkeS. Improving safety and documentation in intrahospital transport: development of an intrahospital transport tool for critically ill patients. Intensive Crit Care Nurs. 2010;26:101-107.
21.
MikkelsenMEGaieskiDFGoyalM. Factors associated with nonadherence to early goal-directed therapy in the ED. Chest. 2010;138:551-558.
22.
HernandezGCastroRRomeroC. Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?J Crit Care. 2011;26:435.e9-435.e14.
23.
KangYRUmSWKohWJ. Initial lactate level and mortality in septic shock patients with hepatic dysfunction. Anaesth Intensive Care. 2011;39:862-867.
24.
CobaVWhitmillMMooneyR. Resuscitation bundle compliance in severe sepsis and septic shock: improves survival, is better late than never. J Intensive Care Med. 2011;26:304-313.
25.
LevrautJIchaiCPetitICiebieraJPPerusOGrimaudD. Low exogenous lactate clearance as an early predictor of mortality in normolactatemic critically ill septic patients. Crit Care Med. 2003;31:705-710.
26.
ArnoldRCShapiroNIJonesAE. Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis. Shock. 2009;32:35-39.
27.
JonesAEShapiroNITrzeciakSArnoldRCClaremontHAKlineJA. Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA. 2010;303:739-746.
28.
ArnoldRCShapiroNIJonesAE. Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis. Shock. 2009;32:35-39.
29.
NguyenHBRiversEPKnoblichBP. Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med. 2004;32:1637-1642.
30.
MerxMWWeberC. Sepsis and the heart. Circulation. 2007;116:793-802.
31.
HollenbergSMAhrensTSAnnaneD. Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med. 2004;32:1928-1948.
32.
OtsujiY. Easy echo diagnosis for hypotension and shock [in Japanese]. J UOEH. 2008;30:431-442.
33.
GriffeeMJMerkelMJWeiKS. The role of echocardiography in hemodynamic assessment of septic shock. Crit Care Clin. 2010;26:365-382.
34.
HiltonAK. Echocardiography is the best cardiovascular ‘monitor’ in septic shock. Crit Care Resusc. 2006;8:247-251.
35.
JosephMXDisneyPJDa CostaRHutchisonSJ. Transthoracic echocardiography to identify or exclude cardiac cause of shock. Chest. 2004;126:1592-1597.
36.
YanagawaYNishiKSakamotoTOkadaY. Early diagnosis of hypovolemic shock by sonographic measurement of inferior vena cava in trauma patients. J Trauma. 2005;58:825-829.
37.
HeZQiaoHZhouW. Assessment of cardiac preload status by pulse pressure variation in patients after anesthesia induction: comparison with central venous pressure and initial distribution volume of glucose [published online ahead of print September 21, 2011]. J Anesth. doi:10.1007/s00540-011-1225-110.1007/s00540-011-1225-1.
38.
GruenewaldMMeybohmPKoernerS. Dynamic and volumetric variables of fluid responsiveness fail during immediate postresuscitation period. Crit Care Med. 2011;39:1953-1959.
KumarARobertsDWoodKE. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34:1589-1596.
41.
KumarAEllisPArabiY. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest. 2009;136:1237-1248.
42.
PinesJM. Timing of antibiotics for acute, severe infections. Emerg Med Clin North Am. 2008;26:245-257.
43.
PinesJMHollanderJEDatnerEMMetlayJP. Pay for performance for antibiotic timing in pneumonia: caveat emptor. Jt Comm J Qual Patient Saf. 2006;32:531-535.
44.
GaieskiDFMikkelsenMEBandRA. Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med. 2010;38:1045-1053.
45.
MurphyCVSchrammGEDohertyJA. The importance of fluid management in acute lung injury secondary to septic shock. Chest. 2009;136:102-109.
SprungCLAnnaneDKehD; CORTICUS Study Group. Hydrocortisone therapy for patients with septic shock. N Engl J Med. 2008;358:111-124.
48.
AnnaneDSebilleVTrocheGRaphaelJCGajdosPBellissantE. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA. 2000;283:1038-1045.
49.
Lipiner-FriedmanDSprungCLLaterrePF. Adrenal function in sepsis: the retrospective Corticus cohort study. Crit Care Med. 2007;35:1012-1018.
ArabiYMAljumahADabbaghO. Low-dose hydrocortisone in patients with cirrhosis and septic shock: a randomized controlled trial. CMAJ. 2010;182:1971-1977.
52.
ArnoldHMMicekSTSkrupkyLPKollefMH. Antibiotic stewardship in the intensive care unit. Semin Respir Crit Care Med. 2011;32:215-227.
53.
TothNRChambersRMDavisSL. Implementation of a care bundle for antimicrobial stewardship. Am J Health Syst Pharm. 2010;67:746-749.
54.
ShimeNSatakeSFujitaN. De-escalation of antimicrobials in the treatment of bacteraemia due to antibiotic-sensitive pathogens in immunocompetent patients. Infection. 2011;39:319-325.
55.
MastertonRG. Antibiotic de-escalation. Crit Care Clin. 2011;27:149-162.
56.
NguyenHBCorbettSWSteeleR. Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality. Crit Care Med. 2007;35:1105-1112.
