Lung Mechanics Determinations at the Bedside: Instrumentation and Clinical Application

Marini JJ , Rodriguez RM , Lamb VJ . Bedside estimation of the inspiratory work of breathing during mechanical ventilation. Chest 1986;89:56–63.

Truwit JD , Marini JJ . Evaluation of thoracic mechanics in the ventilated patient. Part I: Primary measurements. J Crit Care 1988;3(2):133–150.

Gay PC , Rodarte JR , Tayyab M , Hubmayr RD . Evaluation of bronchodilator responsiveness in mechanically ventilated patients. Am Rev Respir Dis 1987;136:880–885.

Pepe PE , Marini JJ . Occult positive end-expiratory pressure in mechanically ventilated patients with airflow obstruction. Am Rev Respir Dis 1982;126:166–170.

Black LF , Hyatt RE . Maximal respiratory pressures. Normal values and relationship to age and sex. Am Rev Respir Dis 1969;99:696–702.

Sahn SA , Lakshminarayan S. Bedside criteria for discontinuation of mechanical ventilation. Chest 1973;63:1002–1005.

Marini JJ , Smith TC , Lamb VJ . Estimation of inspiratory muscle strength in mechanically ventilated patients: The measurement of maximal inspiratory pressure. J Crit Care 1986;1(1):32–38.

Whitelaw WS , Derenne JP , Milic-Emili J. Occlusion pressure as a measure of respiratory center output in conscious man. Respir Physiol 1975;23:181–199.

Holle RHO , Schoene RB , Pavlin EJ . Effect of respiratory muscle weakness on P0.1 induced by partial curarization. J Appl Physiol 1984;57:1150–1157.

Marini JJ , Rodriguez RM , Lamb VJ . The inspiratory workload of patient-initiated mechanical ventilation. Am Rev Respir Dis 1986;134:902–909.

Taylor RF , Marini JJ , Smith TC , Lamb VJ . Bedside estimation of respiratory drive during machine assisted ventilation (abstract). Am Rev Respir Dis 1987;135(4, Part 2):A51.

Rossi A , Gottfried SB , Zocchi L , . Measurement of static compliance of the total respiratory system in patients with acute respiratory failure during mechanical ventilation: The effect of intrinsic positive end-expiratory pressure. Am Rev Respir Dis 1985;131:672–677.

Hoffman BA , Ershowsky P , Krieger BP . Determination of auto-PEEP during spontaneous and controlled ventilation by monitoring changes in end-expiratory thoracic gas volume. Chest 1989;96:613–616.

Marini JJ . Hemodynamic monitoring with the pulmonary artery catheter. Crit Care Clin 1986;2:551–572.

Milic-Emili J , Henderson JAM , Dolovich MB , Trop D , Kaneko K. Regional distribution of inspired gas in the lung. J Appl Physiol 1966;21:749–759.

Marini JJ , Culver BH , Butler J. Effect of positive end-expiratory pressure on canine ventricular function curves. J Appl Physiol: Respirat Environ Exercise Physiol 1981;51:1367–1374.

Milic-Emili J , Mead J , Turner JM . Topography of esophageal pressure as a function of posture in man. J Appl Physiol 1964;19:212–216.

Knowles JH , Henry SK , Rahn H. Possible errors using esophageal balloon in determination of pressure-volume characteristics of the lung and thoracic cage. J Appl Physiol 1959;14:525–530.

Duncan C , Erickson R. Pressures associated with chest tube stripping. Heart Lung 1982;11:166–171.

McMahon SM , Permutt S , Proctor DF . A model to evaluate pleural surface pressure measuring devices. J Appl Physiol 1969;27:886–891.

Macklem PT . Procedures for standardized measurements of lung mechanics. Bethesda MD: National Health Institute, Division of Lung Disease, 1974.

Milic-Emili J , Mead J , Turner JM , . Improved technique for estimating pleural pressure from esophageal balloons. J Appl Physiol 1964;19:207–211.

Gillespie DJ . Comparison of intraesophageal balloon pressure measurements with a nasogastric-esophageal balloon system in volunteers. Am Rev Respir Dis 1982;126:583–585.

Baydur A , Behrakis K , Zin A , Jaeger M , Milic-Emili J. A simple method for assessing the validity of esophageal balloon technique. Am Rev Respir Dis 1982;126:788–791.

Gottfried SB , Rossi A , Higgs BD , . Noninvasive determination of respiratory system mechanics during mechanical ventilation for acute respiratory failure. Am Rev Respir Dis 1985;131:414–420.

Osborn JJ , Wilson RM . Monitoring the mechanical properties of the lung. In: Spence AA , editor. Respiratory monitoring in intensive care. New York: Churchill Livingstone, 1982.

Sullivan WJ , Peters GM , Enright PL . Pneumotachographs: Theory and clinical application. Respir Care 1984;29:736–749.

Gelfand R , Lambertsen CJ , Peterson RE , Slater A. Pneumotachograph for flow and volume measurement in normal and dense atmospheres. J Appl Physiol 1976;41:120–124.

Ruppel G. Manual of pulmonary function testing. 4th ed. St Louis: CV Mosby, 1986.

Grenvik A , Hedstrand U , Sjogren H. Problems in pneumotachography. Acta Anaesthesiol Scand 1966;10:147–155.

McPherson SP . Bedside measurement and monitoring devices. In: Respiratory therapy equipment. 3rd ed. St Louis: CV Mosby, 1985:205–229.

Osborn JJ . A flowmeter for respiratory monitoring. Crit Care Med 1978;6:349–351.

Cox LA , Almeida AP , Robinson JS , Horsley JK . An electronic respirometer. Br J Anaesth 1974;46:302–310.

Blumenfield W , Turney SZ , Denman RJ . A coaxial ultrasonic pneumotachometer. Med Biol Eng 1975;855–862.

Capps JS , Hicks GH . Monitoring non-gas respiratory variables during mechanical ventilation. Respir Care 1987;32:558–571.

Bendixen HH , Egbert LD , Hedley-Whyte J , . Management of patients undergoing prolonged artificial respiration. In: Hedley-Whyte J , Burgess GE , editors. Respiratory care. St Louis: CV Mosby, 1965:149.

Ashutosh K , Auchincloss JH , Gilbert R. Passive spirometry used to evaluate pulmonary function in patients receiving mechanical assistance to ventilation. Chest 1975;68:645–650.

Tuxen DV , Lane S. The effects of ventilatory pattern on hyperinflation, airway pressures, and circulation in mechanical ventilation of patients with severe airflow obstruction. Am Rev Respir Dis 1987;136:872–879.

Bartel LP , Bazik JR , Powner DJ . Compression volume during mechanical ventilation: Comparison of ventilators and tubing circuits. Crit Care Med 1985;13:851–854.

Konno K , Mead J. Measurement of separate volume changes of rib cage and abdomen during breathing. J Appl Physiol 1967;22:407–422.

Hanning CD , Spence AA . Measurement of lung volumes and respiratory frequency. In: Spence AA , editor. Respiratory monitoring in intensive care. New York: Churchill Livingstone, 1982.

Baker LE , Hill DW . The use of electrical impedance techniques for the monitoring of respiratory pattern during anaesthesia. Br J Anaesth 1969;41:2–17.

Ashutosh K , Gilbert R , Auchincloss JH , Erlebacher J , Peppi D. Impedance pneumotachograph and magnetometer methods for monitoring Vr. J Appl Physiol 1974;37:964–966.

Rees PJ , Higenbottam TW , Clark TJH . Use of a single pair of magnetometer coils to monitor breathing patterns in an intensive care unit. Thorax 1980;35:384–388.

Chadha TS , Watson H , Birch S , . Validation of respiratory inductive plethysmography using different calibration procedures. Am Rev Respir Dis 1982;125:644–649.

Dolfin T , Duffty P , Wilkes DL , Bryan MH . Calibration of respiratory induction plethysmography (Respitrace) in infants. Am Rev Respir Dis 1982;126:577–579.

Tobin MJ , Chadha TS , Jenouri G , Birch SJ , Gazeroglu HB , Sackner WH . Breathing patterns. Part 2: Diseased subjects. Chest 1983;84:286–294.

Tobin MJ , Perez W , Guenther SM , . The pattern of breathing during successful and unsuccessful trials of weaning from mechanical ventilation. Am Rev Respir Dis 1986;134:1111–1118.

Marini JJ , Rodriguez RM , Lamb VJ . Involuntary breath stacking. An alternative method for vital capacity estimation in poorly cooperative subjects. Am Rev Respir Dis 1986;134:694–698.

Truwit JD , Marini JJ . Evaluation of thoracic mechanics in the ventilated patient. Part II: Applied mechanics. J Crit Care 1988;3(3):199–213.

Katz JA , Zinn SE , Ozanne GM , Fairley HB . Pulmonary chest wall and lung-thorax elastances in acute respiratory failure. Chest 1981;80:304–311.

Comroe JH , Forster RE , DuBois AB , Briscoe WA , Carlsen E. The lung-Clinical physiology and pulmonary function tests. 2nd ed. Chicago: Year Book Medical Publishers, 1955:178–189.

Rahn H , Otis AB , Chadwick LE , . The pressure-volume diagram of the thorax and lung. Am J Physiol 1946;146:161–178.

Matamis D , LeMaire F , Harf A , Bruin-Buisson C , Ansquer JC , Atlan G. Total respiratory pressure volume curves in the adult respiratory distress syndrome. Chest 1984;86:58–66.

Suter PM , Fairley HB , Isenberg MD . Optimum end-expiratory pressure in patients with acute pulmonary failure. N Engl J Med 1975;292:284–289.

Bone RC . Monitoring ventilatory mechanics in acute respiratory failure. Respir Care 1983;28:597–603.

Von Neergaard K , Wirz K. Die Messung der Stromungs-widerstande in den Atemwegen des Menschen, insbesondere bie Asthma und Emphysem. Z Klin Med 1927;105:51–82.

Briscoe WA , DuBois AB . The relationship between airway resistance, airway conductance and lung volume in subjects of different age and body size. J Clin Invest 1958;37:1279–1285.

Smith TC , Marini JJ . Impact of PEEP on lung mechanics and work of breathing in severe airflow obstruction. The effect of PEEP on auto-PEEP. J Appl Physiol 1988;65:1488–1499.

Truwit J , Marini J. Bedside prediction of auto-PEEP from exponential decay characteristics (abstract). FASEB Journal 1988;2:A1271.

Fallat RJ . Respiratory monitoring. In: Bone RC , editor. Critical care: A comprehensive approach. Park Ridge IL: American College of Chest Physicians, 1984:189–205.

Marini JJ . Monitoring during mechanical ventilation. Clin Chest Med 1988;9:73–100.

Corbeil C , Cantineau JP , Albala M , . Effect of flow and volume on respiratory system resistance in anesthetized-paralyzed humans (abstract). Am Rev Respir Dis 1989;139(4, Part 2):A100.

Bates JH , Rossi A , Milic-Emili J. Analysis of the behaviour of the respiratory system with constant inspiratory flow. J Appl Physiol 1985;58:1840–1848.

Rossi A , Gottfried SB , Higgs BD , Zocchi L , Grassino A , Milic-Emili J. Respiratory mechanics in mechanically ventilated patients with respiratory failure. J Appl Physiol 1985;58:1849–1858.

Mead J , Whittenberger JL . Evaluation of airway interruption technique as a method for measuring airflow resistance. J Appl Physiol 1954;6:408–416.

Von Neergaard K , Wirz K. Uber eine Methode zur Messung der Lungenelastizitat am lebenden Menschen, insbesondere bein Emphysem. Z Klin Med 1927;105:35–51.

Milic-Emili J , Ploysongsang Y. Respiratory mechanics in the adult respiratory distress syndrome. Crit Care Med 1986;14:573–584.

Brody AN . Mechanical compliance and resistance of the lung-thorax calculated from the flow recorded during passive exhalation. Am J Physiol 1954;178:189–196.

Agostoni E , Citterio G , D'Angelo E. Decay rate of inspiratory muscle pressure during expiration in man. Respir Physiol 1979;36:269–285.

Wright P , Marini JJ , Bernard GR . Increased airway resistance contributes to impaired lung mechanics in the adult respiratory distress syndrome (ARDS) (abstract). Am Rev Respir Dis 1988;137(4, Part 2):A137.

Wright PW , Marini JJ , Bernard GR . In vitro versus in vivo comparison of endotracheal tube airflow resistance. Am Rev Respir Dis 1989;140:10–16.

Milic-Emili J. Is weaning an art or a science? Am Rev Respir Dis 1986;134:1107–1108.

Otis AB , Fenn WO , Rahn H. Mechanics of breathing in man. J Appl Physiol 1950;2:592–607.

Marini JJ . Minimizing breathing effort during mechanical ventilation. In: Lemaire F , Zapol WM , editors. Acute respiratory failure. New York: Marcel Dekker, (in press).

Roussos C , Campbell EJM . Respiratory muscle energetics. In: Fishman AP , Macklem PT , Mead J , editors. Handbook of physiology. Bethesda MD: American Physiological Society, 1986:481–510.

Otis AB . The work of breathing. Physiol Rev 1954;34:449–458.

Marini JJ , Smith TC , Lamb VJ . Rapid estimation of the inspiratory work of spontaneous breathing (abstract). Am Rev Respir Dis 1986;133(4, Part 2):A120.

Truwit JD , Marini JJ , Lamb VJ . The work of spontaneous breathing can be predicted noninvasively during mechanical ventilation (abstract). Am Rev Respir Dis 1988;137(4, Part 2):64.

Marini JJ , Capps JS , Culver BH . The inspiratory work of breathing during assisted mechanical ventilation. Chest 1985;87:612–618.

Marini JJ . The role of the inspiratory circuit in the work of breathing during mechanical ventilation. Respir Care 1987;32:419–430.

Petrof BJ , Legare M , Goldberg P , Milic-Emili J , Gottfried SB . Continuous positive airway pressure reduces work of breathing and dyspnea during weaning from mechanical ventilation in severe chronic obstructive pulmonary disease. Am Rev Respir Dis 1990;141:281–289.

Marini JJ . Should PEEP be used in airflow obstruction (editorial)? Am Rev Respir Dis 1989;140:1–3.

Collet PW , Perry C , Engel LA . Pressure-time product, flow, and oxygen cost of resistive breathing in humans. J Appl Physiol 1985;58:1263–1272.

Rochester DF , Bettini G. Diaphragmatic blood flow and oxygen consumption in the dog. J Clin Invest 1976;57:661–672.

Roussos C , Macklem PT . Diaphragmatic fatigue in man. J Appl Physiol 1977;43:189–197.

Milic-Emili J , Grunstein MM . Drive and timing components of ventilation (abstract). Chest 1976;70(Suppl):131–133.

Aubier M , Murciano D , Fournier M , Milic-Emili J , Pariente R , Derenne J-P . Central respiratory drive in acute respiratory failure of patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1980;122:191–199.

Kryger MH , Yacoub O , Dosman J , Macklem PT , Anthonisen NR . Effect of meperidine on occlusion pressure responses to hypercapnia and hypoxia with and without external inspiratory resistance. Am Rev Respir Dis 1976;114:333–340.

Rodarte JR , Rehder K. Dynamics of respiration. In: Fishman AP , Macklem PT , Mead J , editors. Handbook of physiology. Bethesda MD: American Physiological Society, 1986:131–144.

Truwit JD , Lamb VJ , Marini JJ . Validation of a technique to assess maximal inspiratory pressure in poorly cooperative patients (abstract). Am Rev Respir Dis 1989;139(4, Part 2):A98.

Macklem PT . Muscular weakness and respiratory function. N Engl J Med 1986;314:775–776.

Kanarek DJ . Respiratory muscle function and fatigue. In: Miller A , editor. Pulmonary function tests in clinical and occupational lung disease. Orlando FL: Grune & Stratton, 1986:405–411.

Sahn SA , Lakshminarayan S , Petty TL . Weaning from mechanical ventilation. JAMA 1976;235:2208–2212.

Bigland-Ritchie B. Muscle fatigue and the influence of changing neural drive. Clin Chest Med 1984;5:21–34.

Gross D , Grassino A , Ross WRD , Macklem PT . Electromyogram pattern of diaphragmatic fatigue. J Appl Physiol 1979;46:1–7.

Sassoon CSH , Te TT , Mahutte CK , Light RW . Airway occlusion pressure. An important indicator for successful weaning in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1987;135:107–113.

Montgomery AB , Holle RHO , Neagley SR , Pierson DJ , Schoene RB . Prediction of successful ventilator weaning using airway occlusion pressure and hypercapnic challenge. Chest 1987;91:496–499.

Cohen C , Zagelbaum D , Gross D , Roussos C , Macklem PT . Clinical manifestations of inspiratory muscle fatigue. Am J Med 1982;73:308–316.

Krieger BP . Ventilatory pattern monitoring. Respir Care 1990;35:697–708.

Field S , Sanci S , Grassino A. Respiratory muscle oxygen consumption estimated by the diaphragm pressure-time index. J Appl Physiol 1984;57:44–51.

Bellemare F , Grassino A. Effect of pressure and timing of contraction on human diaphragm failure. J Appl Physiol 1982;53:1190–1195.

Grassino A , Macklem PT . Respiratory muscle fatigue and ventilatory failure. Ann Rev Med 1984;35:625–647.

Roussos C. Ventilatory muscle fatigue governs breathing frequency. Bull Eur Physiopathol Respir 1984;20:445–451.