DavidsonM, TempestB, PalmerDL. Bacteriologic diagnosis of acute pneumonia. Comparison of sputum, transtracheal aspirates, and lung aspirates. JAMA1976;235:158–163.
2.
LaForceFM. Hospital-acquired gram-negative rod pneumonias: An overview. Am J Med1981;70:664–669.
3.
StevensRM, TeresD, SkillmanJJ, FinegoldDS. Pneumonia in an intensive care unit. Arch Intern Med1974;134:106–111.
4.
CraigCP, ConnellyS.Effect of intensive care unit nosocomial pneumonia on duration of stay and mortality. Am J Infection Control1984;12:233–238.
5.
BellRC, CoalsonJJ, SmithJD, JohansonWC. Multiple organ system failure and infection in the adult respiratory distress syndrome. Ann Intern Med1983;99:293–298.
6.
HaleyRW, HootonTM, CulverDH, . Nosocomial infections in U.S. hospitals, 1975-1976. Estimated frequency by selected characteristics of patients. Am J Med1981;70:947–959.
7.
JohansonWC, PierceAK, SanfordJP. Changing pharyngeal bacterial flora of hospitalized patients. Emergence of gram-negative bacilli. N Engl J Med1969;281:1137–1140.
8.
BrittMR, SchleupnerCJ, MatsumiyaS.Severity of underlying disease as a predictor of nosocomial infection. JAMA1978;239:1047–1051.
9.
GaribaldiRA, BrittMR, ColemanML, . Risk factors for postoperative pneumonia. Am J Med1981;70:677–680.
10.
HootonTM, HaleyRW, CulverDH. A method for classifying patients according to the nosocomial infection risks associated with diagnoses and surgical procedures. Am J Epidemiol1980;111:556–573.
11.
HuxleyEJ, ViroslavJ, GrayWR, PierceAK. Pharyngeal aspiration in normal adults and patients with depressed consciousness. Am J Med1978;64:564–568.
12.
CameronJL, ReynoldsJ, ZuidemaCD. Aspiration in patients with tracheostomies. Surg Gynecol Obstet1973;136:68–70.
13.
SprayS, ZuidemaG, CameronJL. Aspiration pneumonia. Incidence of aspiration with endotracheal tubes. Am J Surg1976;131:701–703.
14.
CulverGA, MakelHP, BeecherHK. Frequency of aspiration of gastric contents by the lungs during anesthesia and surgery. Ann Surg1951;133:289–292.
15.
van UffelenR, van SaeneHKF, LowenbergA.Oropharyngeal flora as a source of bacteria colonizing the lower airways in patients on artificial ventilation. Intensive Care Med1984;10:233–237.
16.
Du MoulinGC, PatersonDG, Hedley-WhyteJ, LisbonA.Aspiration of gastric bacteria in antacid-treated patients: A frequent cause of postoperative colonisation of the airway. Lancet1982;1:242–245.
17.
BartlettJG, GorbachSL. The triple threat of aspiration pneumonia. Chest1975;68:560–566.
18.
GreenGM. The J Burns Amberson lecture: In defense of the lung. Am Rev Respir Dis1970;102:691–703.
19.
MakiDG. Oropharyngeal ecology. N Engl J Med1970;282:814–815.
20.
MurrayPR, RosenblattJE. Bacterial interference by oropharyngeal and clinical isolates of anaerobic bacteria. J Infect Dis1976;134:281–285.
21.
RosenthalS, TagerI.Prevalence of gram-negative rods in the normal pharyngeal flora. Ann Intern Med1975;83:355–357.
22.
ValentiWM, TrudellRG, BentlyDW. Factors predisposing to oropharyngeal colonization with gram-negative bacilli in the aged. N Engl J Med1978;298:1108–1111.
23.
SandersE.Bacterial interference. I. Its occurrence among the respiratory tract flora and characterization of inhibition of group A streptococci by viridans streptococci. J Infect Dis1969;120:698–707.
24.
WoodsDE, StrausDC, JohansonWCJr, BassJA. Factors influencing the adherence of Pseudomonas aeruginosa to mammalian buccal epithelial cells. Rev Infect Dis1983;5(Suppl):S846–S851.
25.
LorberB, SwensonRM. Bacteriology of aspiration pneumonia. A prospective study of community- and hospital-acquired caes. Ann Intern Med1974;81:329–331.
26.
BjerkestrandG, DigranesA, SchreinerA.Bacteriologic findings in transtracheal aspirates from patients with chronic bronchitis and bronchiectasis. Scand J Respir Dis1975;56:201–207.
27.
Fuxench-LopezZ, Ramirez-RondaCH. Pharyngeal flora in ambulatory alcoholic patients. Prevalence of gram-negative bacilli. Arch Intern Med1978;138:1815–1816.
28.
HaasH, MorrisJF, SamsonS, . Bacterial flora of the respiratory tract in chronic bronchitis: Comparison of transtracheal, fiberbronchoscopic, and oropharyngeal sampling methods. Am Rev Respir Dis1977;116:41–47.
29.
LeesAW, McNaughtW.Bacteriology of lower respiratory tract secretions, sputum, and upper respiratory tract secretions in "normals" and chronic bronchitis. Lancet1959;2:1112–1115.
30.
SmithCB, GoldenCA, KannerRE, RenzettiAD. Hemophilus influenzae and Hemophilus parainfluenzae in chronic obstructive pulmonary disease. Lancet1976;1:1253–1255.
31.
JohansonWG, PierceAK, SanfordJP, ThomasGD. Nosocomial respiratory infections with gram-negative bacilli: The significance of colonization of the respiratory tract. Ann Intern Med1972;77:701–706.
32.
SchwartzSN, DowlingJN, BenkovicC, . Sources of gram-negative bacilli colonizing the trachea of intubated patients. J Infect Dis1978;138:227–231.
33.
SeidenfeldJJ, PohlDF, BellRC, . Incidence, site, and outcome of infections in patients with the adult respiratory distress syndrome. Am Rev Respir Dis1986;134:12–16.
34.
SalataRA, LedermanMM, ShlaesDM, . Diagnosis of nosocomial pneumonia in intubated, intensive care unit patients. Am Rev Respir Dis1987;135:426–432.
AndrewsCP, CoalsonJJ, SmithJD, JohansonWGJr. Diagnosis of nosocomial bacterial pneumonia in acute, diffuse lung injury. Chest1981;80:254–258.
40.
FowlerAA, HammanRF, GoodJT, . Adult respiratory distress syndrome: Risk with common predispositions. Ann Intern Med1983;98:593–597.
41.
MurrayPR, WashingtonJAII. Microscopic and bacteriologic analysis of sputum. Mayo Clin Proc1975;50:339–344.
42.
HeinemanHS, ChawlaJK, LoftonWM. Misinformation from sputum culture without microscopic examination. J Clin Microbiol1977;6:518–527.
43.
BryantLR, TrinkleJK, Mobin-UddinK, . Bacterial colonization profile with tracheal intubation and mechanical ventilation. Arch Surg1972;104:647–651.
44.
BartlettJG, AlexanderJ, MayhewJ, . Should fiberoptic bronchoscopy aspirates be cultured?Am Rev Respir Dis1976;114:73–78.
45.
WimberleyN, FalingLJ, BartlettJG. A fiberoptic bronchoscopy culture. Am Rev Respir Dis1979;119:337–343.
46.
ChastreJ, ViauF, BrunP, . Prospective evaluation of the protected specimen brush for the diagnosis of pulmonary infections in ventilated patients. Am Rev Respir Dis1984;130:924–929.
47.
MatthewEB, HolstromFMG, KasparRL. A simple method for diagnosing pneumonia in intubated or tracheostomized patients. Crit Care Med1977;5:766–81.
48.
BandtPD, BlankN, CastellinoRA. Needle diagnosis of pneumonitis. Value in high-risk patients. JAMA1972;220:1578–1580.
49.
CastellinoRA, BlankN.Etiologic diagnosis of focal pulmonary infection in immunocompromised patients by fluoroscopically guided percutaneous needle aspiration. Radiology1979;132:563–567.
50.
WallaceJM, BatraP, GongH, OvenforaC-O. Percutaneous needle lung aspiration for diagnosing pneumonitis in the patient with acquired immunodeficiency syndrome (AIDS). Am Rev Respir Dis1985;131:389–392.
51.
BroaddusC, DakeMD, StulbargMS, . Bronchoalveolar lavage and transtracheal biopsy for the diagnosis of pulmonary infections in the acquired immunodeficiency syndrome. Ann Intern Med1985;102:747–752.
MontgomeryAB, StagerMA, CarricoCJ, HudsonLD. Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis1985;132:485–489.
55.
GoodpastureHC, RomigDA, VothDW, . A prospective study of tracheobronchial bacterial flora in acutely brain-injured patients with and without antibiotic prophylaxis. J Neurosurg1977;47:228–235.
56.
SpruntK, RedmanW.Evidence suggesting importance of role of interbacterial inhibition in maintaining balance of normal flora. Ann Intern Med1968;68:579–590.
57.
DonowitzGR, MandellGL. Empiric therapy for pneumonia. Rev Infect Dis1983;5(Suppl):S40–S51.
58.
BartlettJG, GorbachSL. Penicillin or clindamycin for primary lung abscess. Ann Intern Med1983;98:546–548.
59.
LevisonME, ManguarCT, LorberG, . Clindamycin compared with penicillin for the treatment of anaerobic lung abscess. Ann Intern Med1983;98:466–468.
60.
FransonTR, DaMertGJ, SethNK, . Institution-specific versus published in-vitro antimicrobial susceptibility data in making formulary decisions. Am J Hosp Pharm1987;44:95–101.
61.
QuinnJP, DiVincenzoDA, FosterJ.Emergence of resistance to ceftazidime during therapy for Enterobacter cloacae infections. J Infect Dis1987;155:942–947.
62.
SandersCC, SandersWE. Emergence of resistance during therapy with newer beta-lactam antibiotics: Role of inducible beta-lactamases and implications for the future. Rev Infect Dis1983;5:639–648.
63.
ArnoffSC, ShlaesDM. Factors that influence the evolution of beta-lactam resistance in beta-lactamase-inducible strains of Enterobacter cloacae and Pseudomanas aeruginosa. J Infect Dis1987;155:936–941.
64.
NeuHC. The emergence of bacterial resistance and its influence on empiric therapy. Rev Infect Dis1983;5(Suppl):S9–S20.
65.
SaltaRA, GebhartRL, PalmerDL, . Pneumonia treated with imipenem/cilastinAm J Med1985;78:104–109.
66.
CipolleRJ, SeifertRD, ZaskeDE, StrateRG. Hospital acquired gram-negative pneumonias: Response rate and dose requirements with individualized tobramycin therapy. Ther Drug Monit1980;2:359–363.
67.
SawchukRJ, ZaskeDE, CipolleRJ, . Kinetic model for gentamicin dosing with the use of individual patient parameters. Clin Pharmacol Ther1977;21:362–365.
68.
MooreRD, LietmanPS, SmithCR. Clinical response to aminoglycoside therapy: Importance of the ratio of peak concentration to minimal inhibitory concentration. J Infect Dis1987;155:93–99.
