The syndrome bronchopulmonary dysplasia (BPD) is a well-known complication of mechanical ventilation, tracheal intubation, and oxygen therapy in the newborn. However, its appearance in the adult has been reported only recently. We describe the clinical course and autopsy findings of a young woman who developed BPD during mechanical ventilation despite our attempts to reduce inspired oxygen concentration (FIO2) and a trial of high frequency jet ventilation (HFJV). (Respir Care 1985;30:759-763.)
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References
1.
NorthwayWHJr, RosanRC, PorterDY. Pulmonary disease following respiratory therapy of hyaline-membrane disease: Bronchopulmonary dysplasia. N Engl J Med1967;276:357–368.
2.
PuseyVA, MacPhersonRI, ChernickV.Pulmonary fibroplasia following prolonged artificial ventilation of newborn infants. Can Med Assoc J1969;100:451–457.
3.
BarnesND, GloverWJ, HullD, MilnerAD. Effects of prolonged positive pressure ventilation in infancy. Lancet1969;2:1096–1099.
4.
AndersonRW, StricklandMB. Pulmonary complications of oxygen therapy in the neonate. Arch Pathol1971;91:506–513.
5.
LamarreA, LinsaoL, ReillyBJ, SwyerPR, LevisonH.Residual pulmonary abnormalities in survivors of idiopathic respiratory distress syndrome. Am Rev Respir Dis1973;108:56–63.
6.
LakshminarayanS, StanfordRE, PettyTL. Prognosis after recovery from adult respiratory distress syndrome. Am Rev Respir Dis1976;113:7–16.
7.
KleinJJ, Van HaeringenJR, SluiterHJ, HollowayR, PesetR.Pulmonary function after recovery from the adult respiratory distress syndrome. Chest1976;69:350–355.
8.
HurstJH, DeHavenCB, BransonRD, SolomkinJS. HFJV and hypothermia in ARDS. Crit Care Med (in press).
9.
TaghizadehA, ReynoldsEOR. Pathogenesis of broncho-pulmonary dysplasia following hyaline-membrane disease. Am J Pathol1976;82:241–258.
10.
NorthwayWH, PetriceksR, CantyE, BenschKG. Maturation as a factor in pulmonary oxygen toxicity: A preliminary report. J Pediatr1979;95:859–864.
11.
BrownER. Increased risk of bronchopulmonary dysplasia in infants with patent ductus arteriosus. J Pediatr1979;95:865–866.
12.
FarrellPM. Vitamin E deficiency in premature infants. J Pediatr1979;95:869–872.
13.
StahlmanMT, CheathamW, GrayME. The role of air-dissection in bronchopulmonary dysplasia. J Pediatr1979;95:878–882.
14.
FarrellP.BPD—Causes, prevention, and therapy: Discussion. J Pediatr1979;95:885–888.
15.
PhillipAGS. Oxygen plus pressure plus time: The etiology of bronchopulmonary dysplasia. Pediatrics1975;55:44–50.
16.
ChurgA, GoldenJ, FligelS, HoggJC. Bronchopulmonary dysplasia in the adult. Am Rev Respir Dis1983;127:117–120.
17.
BanerjeeCK, GirlingDJ, WigglesworthJS. Pulmonary fibroplasia in newborn babies treated with oxygen and artificial ventilation. Arch Dis Child1972;47:509–518.
18.
EdwardsDK, DyerUM, NorthwayWHJr. Twelve years experience with bronchopulmonary dysplasia. Pediatrics1977;59:839–846.
19.
de LemosR, WolfsdorfJ, NachmanR, . Lung injury from oxygen in lambs; The role of artificial ventilation. Anesthesiology1969;30:609–618.
20.
PyrlesVC. Staphylcoccal pneumonia in infancy and childhood. Pediatrics1958;21:609–623.
21.
ConwayDJ. The origin of lung cysts in childhood. Arch Dis Child1951;26:504–529.
22.
BoissettGF. Subpleural emphysema complicating staphy-lococcal and other pneumonias. J Pediatr1972;81:259–266.
23.
JohansonWG, PierceAK, SanfordJP, ThomasGD. Nosocomial respiratory infections with gram-negative bacilli. Ann Intern Med1972;77:701–706.
24.
JohansonWG, WoodsDE, ChaudhuriT.Association of respiratory tract colonization with adherence of gram-negative bacilli to epithelial cells. J Infect Dis1979;139:667–673.
25.
JohansonWG, HiguchiJH, ChaudhuriT, WoodsDE. Bacterial adherence to epithelial cells in bacillary colonization of the respiratory tract. Am Rev Respir Dis1980;121:55–63.
26.
LamyM, FallatRJ, KoenigerE, . Pathologic features and mechanisms of hypoxemia in adult respiratory distress syndrome. Am Rev Respir Dis1976;114:267–284.
CullenDJ, CalderaDL. The incidence of ventilator-induced pulmonary barotrauma in critically ill patients. Anesthesiology1979;50:185–190.
29.
ReinesHD. Manifestations of barotrauma in acute respiratory failure. Am J Surg1981;47:421–425.
30.
KumarA, PontoppidanH, FalkeK.Pulmonary barotrauma during mechanical ventilation. Crit Care Med1973;1:181–186.
31.
RobertsonCH, HallDL, HoggJC. A description of lung distortion due to localized pleural stress. J Appl Physiol1973;34:344–350.
32.
FroeseAB. High frequency ventilation: A critical assessment. In:ShoemakerWS, ed. Critical care: State of the art. Fullerton CA: Society of Critical Care Medicine, 1984:1–53.
33.
BeamerWC, ProughDS, RoysterRL, JohnstonWE, JohnsonJC. High frequency jet ventilation produces auto-PEEP. Crit Care Med1984;12:734–737.