We have developed a valved gas collection assembly for high-flow CPAP systems that permits the isolation of expired gases for the analysis and computation of oxygen uptake and carbon dioxide production. Using volunteer subjects we compared the valved assembly with a high-flow valveless CPAP system for volume, pressure, and flow differences at end-expiratory pressure levels of 5, 7, 10, and 12 cm H2O and found that the valve produced no significant differences in the flow/pressure pattern.
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