Here we report a challenging case of a 52-year-old man presenting with subacute constipation, urinary retention, impotence, absent Achilles reflexes, and hypoesthesia in S2-S5 dermatomes. We review the clinical decision-making as the symptoms evolved and diagnostic testing changed over time. Once the diagnosis is settled, we discuss the sign and symptoms, additional diagnostic tools, treatment options and prognosis.
SavoldiFKaufmannTJFlanaganEPToledanoMWeinshenkerBG. Elsberg syndrome a rarely recognized cause of cauda equina syndrome and lower thoracic myelitis. Neurol Neuroimmunol Neuroinflamm. 2017;4(4):e355.
4.
BeristainXBiagioA. The neurological masquerade of intravascular lymphomatosis. Arch Neurol. 2002;59(3):439–443.
5.
PonzoniMFerreriAJM. Intravascular lymphoma: a neoplasm of ‘homeless’ lymphocytes?Hematol Oncol. 2006;24(3):105–112.
6.
KumarNKeeganBMRodriguezFJHammackJEKantarciOH. Intravascular lymphoma presenting as a longitudinally-extensive myelitis: diagnostic challenges and etiologic clues. J Neurol Sci. 2011;303(1-2):146–149.
7.
AbuzinadahAAlmalikYShabani-RadMT, et al.Cauda equina syndrome secondary to intravascular lymphoma. Neurol Clin Pract. 2012;2(2):158–161.
8.
FischerMIglsederSGramsA, et al.Intravascular large B-cell lymphoma mimicking central nervous system vasculitis. J Clin Case Rep. 2016;6(4):3–8.
9.
OrwatDENicholasIB. Intravascular large B-cell lymphoma. Arch Pathol Lab Med. 2012;136(3):333–338.
10.
MuraseTNakamuraSKawauchiK, et al.An Asian variant of intravascular large B-cell lymphoma: clinical, pathological and cytogenetic approaches to diffuse large B-cell lymphoma associated with haemophagocytic syndrome. Br J Haematol. 2000;111(3):826–834.
11.
CoulibalyBMesturouxLPetitBMagyLLabrousseF. Intravascular large B-cell lymphoma presenting as cauda equina syndrome and showing aberrant cytokeratin expression: a diagnostic challenge. Pathology. 2014;46(3):241–244.
12.
LacomisDSmithTWLongRR. Angiotropic lymphoma (intravascular large cell lymphoma) presenting with cauda equina syndrome. Clin Neurol Neurosurg. 1992;94(4):311–315.
13.
YuYGovindarajanR. Intravascular large B-cell lymphoma presenting as an isolated cauda equina–conus medullaris syndrome—a case report. J Spinal Cord Med. 2018;43(4):556–559.
14.
BaumannTPHurwitzNKaramitopolou-DiamantisEProbstAHerrmannRSteckAJ. Diagnosis and treatment of intravascular lymphomatosis. Arch Neurol. 2000;57(3):374–377.
15.
Tahsili-FahadanPRashidiACiminoPJBucelliRCKeyrouzSG. Neurologic manifestations of intravascular large B-cell lymphoma. Neurol Clin Pract. 2015;6(1):55–60.