Weakness and sensory changes are common complaints in both the inpatient and the outpatient setting. However, this presentation remains a diagnostic challenge to clinicians due to the many possible underlying etiologies. The initial evaluation of weakness and sensory changes starts a thorough history and physical examination to guide the diagnostic process. In this article, we present the case of an elderly woman with complaints of weakness and sensory changes to highlight a step-wise approach to diagnosis and management.
KameshLHarperLSavageC. ANCA-positive vasculitis. J Am Soc Nephrol. 2002;13(7):1953–1960.
2.
RossiCMDi ComiteG. The clinical spectrum of the neurologic involvement of vasculitides. J Neurol Sci. 2009;285(1-2):13–21.
3.
VaglioABuzioCZwerinaJ. Eosinophilic granulomatosis with polyangiitis (Churg Strauss): state of the art. Eur J Allergy Clin Immunol. 2013;68(3):261–273.
4.
KeoghK.Leukotriene receptor antagonists and Churg-Strauss syndrome: cause, trigger or merely an association. Drug Saf. 2007;30(10):837–843.
5.
SinicoRABotteroP. Churg Strauss angiitis. Best Pract Res Clin Rheumatol. 2009;23(3):355–366.
6.
CattaneoLChiericiEPavoneL. Peripheral neuropathy in Wegener’s granulomatosis, Churg Strauss syndrome and microscopic polyangiitis. J Neurol Neurosurg Psychiatry. 2007;78(10):1119–1123.
7.
LanhamJGElkonKBPuseyCDHughesGR. Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg Strauss syndrome. Medicine. 1984:63(2):65–81.
8.
ComarmondCPagnouxCKhellafM. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): clinical characteristics and long term follow-up of the 383 patients enrolled in the French Vasculitis Study Group Cohort. Arthritis Rheum. 2013;65(1):271–281.
9.
WattsRLaneSHanslikT. Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiologic studies. Ann Rheum Dis. 2007;66(2):222–227.
