A phytochemical study of a Venezuelan species Hydrocotyle multifida led to the isolation of five oleanane-type glycosides: two previously undescribed and three known ones. Their structures were established by 2D NMR spectroscopic techniques and mass spectrometry as 3-O-β-D-galactopyranosyl-(1→2)-[α-L-arabinopyranosyl-(1→3)]-β-D-glucuronopyranosyloleanolic acid and 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→2)-β-D-glucuronopyrano-syloleanolic acid. These results represent a significative contribution to the chemotaxonomy of the Hydrocotyle genus.
NicolasA.N., PlunkettG.M. (2009) The demise of subfamily Hydrocotyloideae (Apiaceae) and the re-alignment of its genera across the entire order Apiales. Molecular Phylogenetics and Evolution, 53, 134–151.
2.
BriceñoB., MorilloG. (2002) Catálogo abreviado de las plantas con flores de los páramos de Venezuela. Parte I. Dicotiledóneas (Magnoliopsida). Acta Botánica Venezuélica, 25, 1–46.
3.
SaikiaP., DekaD.C. (2013) Mineral content of some wild green leafy vegetables of North-East India. Journal of Chemical and Pharmaceutical Research, 5, 117–121.
4.
HongL., GuoZ., HuangK., WeiS., LiuB., MengS., LongC. (2015) Ethnobotanical study on medicinal plants used by Maonan people in China. Journal of Ethnobiology and Ethnomedicine, 11, 32.
HuongT.N.L., PhungN.K.P., SuongN.N. (2009) Chemical examination of Hydrocotyle bonariensis L. (Apiaceae). Vietnam Journal of Chemistry, 47, 542–546.
7.
Della GrecaM., FiorentinoA., MonacoP., PreviteraL. (1994) Oleanane glycosides from Hydrocotyle ranunculoides.Phytochemistry, 36, 1479–1483.
8.
MatsushitaA., SasakiY., WarashinaT., MiyaseT., NoguchiH., Vander VeldeD. (2004) Hydrocotylosides I-VII, new oleanane saponins from Hydrocotyle sibthorpioides.Journal of Natural Products, 67, 384–388.
9.
SosaA., Rosquete PorcarC., RojasL.B., PouységuL., QuideauS., PaululatT., Mitaine-OfferA.C., Lacaille-DuboisM.A. (2011) New triterpenoid and ergostane glycosides from the leaves of Hydrocotyle umbellata L. Helvetica Chimica Acta, 94, 1850–1859.
10.
IwamotoM., OkabeH., YamamuchiT. (1985) Studies on the constituents of Momordica cochinchinensis Spreng. II. Isolation and characterization of the root saponins, Momordins I, II and III. Chemical & Pharmaceutical Bulletin, 33, 1–7.
11.
Sánchez-ContrerasS., Díaz-LanzaA.M., BernabéM. (2000) Four new triterpenoid saponins from the roots of Bupleurum rigidum.Journal of Natural Products, 63, 1479–1482.
12.
NieR-L, MoritaT., KasaiR., ZhouJ., WuC-Y, TanakaO. (1984) Saponins from chinese medicinal plants. (1). Isolation and structures of Hemslosides. Planta Medica, 50, 322–327.
13.
HaraS., OkabeH., MihashiK. (1987) Gas-liquid chromatographic separation of aldose enantiomers as trimethylsilyl ethers of methyl 2-(polyhydroxyalkyl)-thiazolidine-4(R)-carboxylates. Chemical & Pharmaceutical Bulletin, 35, 501–506.
14.
AndriamisainaN., Mitaine-OfferA.C., PruvotB., ChlubaJ., MiyamotoT., TanakaC., Lacaille-DuboisM.A. (2018) Phytochemistry of Weigela x “kosteriana variegata”. Natural Product Communications, 13, 403–406.
15.
ChavasiriW., PrukchareonW., SawasdeeP., ZungsontipornS. (2005) Allelochemicals from Hydrocotyle umbellata Linn. in: Proc. 4th World Congr. Allelopath. “Establishing Sci. Base,” pp. 339–342.
