12-Hydroxycorniculatolide a from the Mangrove Tree,Lumnitzera littorea

Abstract

A new macrocyclic lactone, 12-hydroxycorniculatolide A (1), along with three known compounds, corniculatolide A (2), 12-hydroxy-11-O-methyl-corniculatolide A (3) and 6,7-dimethoxycoumarin (4) were isolated from the methanolic extract of the twigs of Lumnitzera littorea. All compounds were characterized using spectroscopic methods. All compounds were screened against a panel of six Gram positive and five Gram negative bacteria.

Keywords

Lumnitzera littorea Macrocyclic lactone 12-Hydroxycorniculatolide A Antibacterial activity

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