The large mushroom genus Tricholoma (Fr.) Staude comprises hundreds of species growing worldwide. Phytochemical studies on the contents of these mushrooms have been increasing steadily in the last decades; this review is the first complete report about the secondary metabolites isolated to date (January 2018) from the fruiting bodies, with the exclusion of most volatile constituents. The structures, presumed biogenesis, and bioactivities of identified compounds, divided in families according to their biogenesis, are critically discussed. A brief chemotaxonomic discussion of the genus Tricholoma is included in the final part of the review.
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