Two new lignans, named (7R, 8S)-balanophonin (1) and (7R, 8S)-tomentosanan A (2), together with eight known lignans, burselignan (3), (+)-isolariciresinol (4), (+)-lyoniresinol (5), 5-methoxy-(+)-isolariciresinol (6), (-)-syringaresinol (7), (+)-epipinoresinol (8), (-)-(7′S, 8S, 8′ R)-4,4′-dihydroxy-3, 3′, 5, 5′-tetramethoxy-7, 9-epoxy-lignan-9′-ol-7-one (9), and (-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol (10) were isolated from the whole plants of Hedyotis uncinella Hook. et Arn. Structures of these compounds were elucidated through 1H NMR, 13C NMR, 2D NMR, ESI-MS and CD data.
WangRJ, ZhaoNX. (2001) The origin and distribution of genus Hedyotis L. Journal of Tropical and Subtropical Botany, 9, 219-228.
2.
Flora of China. (1999) Science Press, 71, 59.
3.
Flora of China. (1974) Science Press, 3, 304.
4.
LiuYH, XuJ, LiQJ, PanLT. (2013) Chemical constituents of Hedyotis uncinella.Chinese Traditional Patent Medicine, 35, 556-559.
5.
WangQH, PengK, TanLH, DaiHF. (2010) Aquilarin A, a new benzenoid derivative from the fresh stem of Aquilaria sinensis.Molecules, 15, 4011-4016.
6.
MatsudaN, SatoH, YaoitaY, KikuchiM. (1996) Isolation and absolute structures of the neolignan glycosides with the enantiomeric aglycones from the leaves of Viburnum awabuki K. KOCH. Chemical and Pharmaceutical Bulletin, 44, 1122-1123.
7.
LiuQB, HuangXX, YanXJ, BaiM, YuLH, HuC, ZhuT, LiL-Z, SongSJ., (2014) Neolignans from the seeds of Prunus tomentosa (Rosaceae) and their chemotaxonomic interest. Biochemical Systematics and Ecology, 55, 236-240.
