The aim of this study was to evaluate the antibacterial activity of essential oil from Chamaecyparis obtusa against general infectious microbes and drug resistant strains of clinical origin. The results indicate that both essential oil and non-volatile residue have broad inhibitory activity against test strains. Essential oil and non-volatile residues showed antimicrobial activity not only against general infectious bacteria, but also against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) strains.
(a) KoyamaS., YamaguchiY., TanakaS., MotoyoshiyaJ. (1997) A new substance (Yoshixol) with an interesting antibiotic mechanism from wood oil of Japanese traditional tree (Kiso-Hinoki), Chamaecyparis obtusa.General Pharmacology, 28, 797–804; (b) An BS, Kang JH, Yang H, Jung EM, Kang HS, Choi IG, Park MJ, Jeung EB. (2013) Anti-inflammatory effects of essential oils from Chamaecyparis obtusa via the cyclooxygenase-2 pathway in rats. Molecular Medicine Reports, 8, 255-259; (c) Lee GS, Hong EJ, Gwak KS, Park MJ, Choi KC, Choi IG, Jang JW, Jeung EB. (2010) The essential oils of Chamaecyparis obtusa promote hair growth through the induction of vascular endothelial growth factor gene. Fitoterapia, 81, 17-24; (d) Sieradzki K, Roberts RB, Haber SW, Tomasz A. (1999) The development of vancomycin resistance in a patient with methicillin-resistant Staphylococcus aureus infection. The New England Journal of Medicine, 340, 517-523.
2.
VenkitanarayananK., Kollanoor-JohnyA., DarreM.J., DonoghueA.M., DonoghueD.J. (2013) Use of plant-derived antimicrobials for improving the safety of poultry products. Poultry Science, 92, 493–501.
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(a) ChienT.C., LoS.F., HoC.L. (2014) Chemical composition and anti-inflammatory activity of Chamaecyparis obtusa f. formosana wood essential oil from Taiwan. Natural Product Communications, 9, 723–726; (b) Jin Y, Han D, Tian M, Row KH. (2010) Supercritical CO2 extraction of essential oils from Chamaecyparis obtusa. Natural Product Communications, 5, 461-464; (c) Kasuya H, Hata E, Satou T, Yoshikawa M, Hayashi S, Masuo Y, Koike K. (2013) Effect on emotional behavior and stress by inhalation of the essential oil from Chamaecyparis obtusa. Natural Product Communications, 8, 515-518; (d) Kasuya H, Iida S, Ono K, Satou T, Koike K. (2015) Intracerebral distribution of α-pinene and the anxiolytic-like effect in mice following inhaled administration of essential oil from Chamaecyparis obtusa. Natural Product Communications, 10, 1479-1482; (e) Bae MS, Shin JS, Lee KY, Lee KH, Kim YJ. (2014) Long-range transport of biomass burning emissions based on organic molecular markers and carbonaceous thermal distribution. Science of the Total Environment, 466-467, 56-66.
4.
IwasaT., HigashideE., ShibataM. (1971) Studies of validamycins, new antibiotics. 3. Bioassay methods for the determination of validamycin. Journal of Antibiotics (Tokyo), 24, 114–118.