Acetylation of the 3,4-seco-derivatives of betulin, allobetulin and 28-oxyallobetulone gave the 5,19-(2,6-dimethylpyridin-4-yl)-4,23,24,20,29,30-hexanorlupane, and 5-(2,6-dimethylpyridin-4-yl)-4,23,24-trisnor-derivatives of oleanane and ursane.
LeeK-H. (2010) Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach. Journal of Natural Products, 3, 500–516.
2.
ShengH, SunH. (2011) Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases. Natural Product Reports, 28, 543–593.
3.
DehaenW, MashentsevaAA, SeitembetovTS. (2011) Allobetulin and its derivatives: Synthesis and biological activity. Molecules, 3, 2443–2466.
4.
KazakovaOB, SmirnovaIE, KhusnutdinovaEF, ZhukovaOS, FetisovaLV, ApryshkoGN, MedvedevaNI, YamansarovEYu, BaikovaIP, NguyenTT, Thi ThuHD. (2014) Synthesis and Cytotoxicity of Allobetulin Derivatives. Russian Journal of Bioorganic Chemistry, 5, 558–567.
5.
KuoR-Y, QianK, Morris-NatschkeSL, LeeK-H. (2009) Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents. Natural Product Reports, 26, 1321–1344.
6.
AntimonovaAN, PetrenkoNI, ShultsEE, PolienkoYuF, ShakirovMM, IrtegovaIG, PokrovskiiMA, ShermanKM, Grigor'evIA, PokrovskiiAG, TolstikovGA. (2013) Synthetic Transformations of Higher Triterpenoids. XXX. Synthesis and Cytotoxic Activity of Betulonic Acid Amides with Fragments of Nitroxyl Radicals. Russian Journal of Bioorganic Chemistry, 2, 181–185.
7.
KhusnutdinovaEF, LopatinaTV, KazakovaOB, AkhmatshinaGF, KukovinetsOS. (2014) Synthesis and cytotoxicity of triterpene A-seco-acid propargylamides. Chemistry of Natural Compounds, 5, 853–856.
8.
KazakovaOB, GiniyatullinaGV, YamansarovEYu, TolstikovGA. (2010) Betulin and ursolic acid synthetic derivatives as inhibitors of Papilloma virus. Bioorganic & Medicinal Chemistry Letters, 20, 4088–4090.
9.
AronsonJK. (2006) Meyler's Side Effects of Drugs (Fifteenth Edition). The International Encyclopedia of Adverse Drug Reactions and Interactions. Elsevier. Pages 1923–1929.
10.
DietrichJ, HulmeC, HurleyLH. (2010) The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: A structural analysis of the binding interactions of Gleevec, Nexavar, and BIRB-796. Bioorganic & Medicinal Chemistry, 18, 5738–5748.
11.
FlekhterOB, KarachurinaLT, NigmatullinaLR, SapozhnikovaTA, BaltinaLA, ZarudiiFS, GalinFZ, SpirikhinLV, TolstikovGA, PlyasunovaOA, PokrovskiiAG. (2002) Synthesis and Pharmacological Activity of Betulin Dinicotinate. Russian Journal of Bioorganic Chemistry, 6, 494–500.
12.
DzhemilevUM, SelimovFA, TolstikovGA. (2001) Metal complex catalysis in a synthesis of pyridine bases. ARKIVOC, 9, 85–116.
13.
AntimonovaAN, PetrenkoNI, ShakirovMM, Shul'tsEE. (2014) Synthesis of 19-(2,6-dimethylpyrid-4-yl)-20,29,30-trinorlupanes. Chemistry of Natural Compounds, 2, 305–310.
14.
LiT-Sh, WangJ-X, ZhengX-J. (1998) Simple synthesis of allobetulin, 28-oxyallobetulin and related biomarkers from betulin and betulinic acid catalysed by solid acids. Journal of the Chemical Society, Perkin Transactions 1, 3957–3965.
15.
KazakovaOB, KhusnutdinovaEF, MedvedevaNI, LobovAN, SuponitskiiKYu. (2012) Molecular structure of 1,2,6,6,10,16,17-heptamethyl-20-(acetoxymethyl)pentacyclo [12.8.0.02.11.05.10.015.20]docos-17-en-7-yl acetate. Journal of Structural Chemistry, 5, 954–957.
16.
KlinotJ, SumanovaV, VystrcilK. (1972) 3,4-Seco derivatives of betulonic acid. Collection of Czechoslovak Chemical Communications, 2, 603–609.
17.
KazakovaOB, MedvedevaNI, YamansarovEYu, SpirikhinLV, KhusnutdinovaEF, KukovinetsOS, TolstikovGA. (2011) Synthesis of vinyl chloride derivatives based on betulin. [In Russian] Khimiya v Interesah Ustoichivogo Razvitiya, 19, 373–376.