Two New Eremophilane Sesquiterpenes and One New Resorcinol from Ligularia Knorringiana

Abstract

Two new eremophilane sesquiterpenes, 12-oxa-1β, 5β,8,9aβ-tetramethyl-4α,5-ethano-4aβ-hydroxy-7β,10aβ-epoxy-9β-angeloyloxy-1,2,3,4,4a,5,6,7,9,9a,10,10a-dodecahydro-anthracen-13-on (knorringianalarin A, 1) and 6,9-dien-8-oxoeremophil-12-nor-11-ketone (knorringianalarin B, 2), and a new resorcinol, 4-acetyl-6-(2-methylpropionyl)-1,3-resorcinol (knorringianalarin C, 3) were isolated from the roots and rhizomes of Ligularia knorringiana, together with three known eremophilane sesquiterpenes (4–6). The structures of the new compounds were identified by spectroscopic methods including 2D-NMR techniques.

Keywords

Ligularia knorringiana Eremophilane sesquiterpenes Resorcinol Knorringianalarin A Knorringianalarin B Knorringianalarin C

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