One new phenyl ethyl glycoside, 2-(4-hydroxyphenyl)ethyl-O-α-L-arabinofuranosyl-(1→6)-O-β-D-glucopyranoside (1) and 11 known compounds (2-12) were isolated from the twigs of Acer tegmentum. Compound 6 showed potent anti-neuroinflammatory activity against the LPS-stimulated BV-2 microglial cells with tNO production of 25.0±2.5 μM and TNF-α concentration of 617.6±47.1 pg/mL at 30 μM.
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