A series of fatty acids were rapidly dereplicated and partially identified from the flowerpot fungus, Leucocoprinus birnbaumii using HPLC-NMR and HPLC-MS. Subsequent off-line isolation unequivocally established the structures, and anti-microbial testing concluded that the fatty acids displayed moderate but selective anti-microbial activity. This represents the first report of these compounds occurring in this particular terrestrial fungus.
AroraD. (1986) Mushrooms Demystified. Ten Speed Press, California.
2.
HallIR, StephensonSC, BuchananPK, YunW, ColeALJ. (2003) Edible and Poisonous Mushrooms of the World. Timber Press, Cambridge, UK.
3.
GoyalR, MisraPS, PathakNC. (1990-1991) Cultivation and nutritive value of Leucocoprinus birnbaumii. Acta Botanica Hungarica, 36, 181–185.
4.
BartschA, BrossM, SpitellerP, SpitellerM, SteglichW. (2005) Birnbaumin A and B: Two unusual 1-hydroxyindole pigments from the “flower pot parasol” Leucocoprinus birnbaumii. Angewandte Chemie, International Edition, 44, 2957–2959.
5.
PrivettOS, NickellC. (1962) Determination of structure of unsaturated fatty acids via reductive ozonolysis. Journal of the American Oil Chemists’ Society, 39, 414–419.
6.
SunC, CurtisJM. (2013) Locating double bonds in lipids - New approaches to the use of ozonolysis. Lipid Technology, 25, 279–282.
7.
FurnissBS, HannafordAJ, SmithPWG, TatchellAR. (1989) Vogel's Textbook of Practical Organic Chemistry. Longman Group UK Limited, Essex, UK
8.
SmithMB, MarchJ. (2001) March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure. Wiley, New York.
RustanAC, DrevonCA. (2001) Fatty acids: Structures and properties, eLS. John Wiley & Sons, Ltd, Chichester, UK.
11.
LedouxM, JuanedaP, SebedioJ-L. (2007) Trans fatty acids: definition and occurrence in foods. European Journal of Lipid Science and Technology, 109, 891–900.
12.
KabaraJJ, SwieczkowskiDM, ConleyAJ, TruantJP. (1972) Fatty acids and derivatives as antimicrobial agents. Antimicrobial Agents and Chemotherapy, 2, 23–28.
13.
DilikaF, BremnerPD, MeyerJJM. (2000) Antibacterial activity of linoleic and oleic acids isolated from Helichrysum pedunculatum: a plant used during circumcision rites. Fitoterapia, 71, 450–452.
14.
MishraPM, SreeA, BaliarsinghS. (2009) Antibacterial study and fatty acid analysis of lipids of the sponge Myrmekioderma granulata. Chemistry of Natural Compounds, 45, 621–624.
15.
SulimanMB, NourAH, YusoffMM, NourAH, KuppusamyP, YuvarajAR, AdamMS. (2013) Fatty acid composition and antibacterial activity of Swietenia macrophylla King seed oil. African Journal of Plant Science, 7, 300–303.
16.
DesboisAP, LawlorKC. (2013) Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus. Marine Drugs, 11, 4544–4557.
17.
SmallcombeSH, PattSL, KeiferPA. (1995) WET solvent solvent suppression and its application to LC NMR and high-resolution NMR spectroscopy. Journal of Magnetic Resonance, Series A, 117, 295–303.
