Three New Isoflavonoids from Erythrina caffra

Abstract

Three new isoflavonoids, 5,7-dihydroxy-2′,4′-dimethoxy-5′-(3-methylbut-2-enyl) isoflavanone (erycaffra A) (1), 5,7-dihydroxy-2′,4′-dimethoxy-5′-(2-hydroxy-3-methylbut-3-enyl)isoflavanone (erycaffra B) (2), and 5,7-dihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)isoflavone (erycaffra C) (3), were isolated from the stem bark of E. caffra Thunb., along with eight known compounds, namely, alpinumisoflavone (4), isoerysenegalensein E (5), β-amyrin (6), oleanolic acid (7), octacosyl-E-ferulate (8), triacontyl-4-hydroxycinnamate (9), n-tetracosyl p-coumarate (10) and octacosan-1-ol (11). The structures were determined on the basis of spectroscopic (1D, 2D-NMR) and MS data and by comparison with literature values.

Keywords

Fabaceae Isoflavanones Isoflavone

References

Tanaka

, Oh-Uchi

, Etoh

, Sako

, Asai

, Fukai

, Sato

, Murata

, Tateishi

(2003) Isoflavonoids from roots of Erythrina zeyheri. Phytochemistry, 64, 753–758.

Miguel-Chavez

R.S.

, Soto-Hernandez

, Ramos-Valdivia

A.C.

, Kite

(2007) Alkaloid production in elicited cell suspension cultures of Erythrina americana Miller. Phytochemistry Review, 6, 167–173.

Chukwujekwu

J.C.

, Van Heerden

F.R.

, Van Staden

(2011) Antibacterial activity of flavonoids from the stem bark of Erythrina caffra Thunb. Phytotherapy Research, 25, 46–48.

Ei-Masry

, Hammoda

H.M.

, Radwan

M.M.

, Ross

S.A.

, Zaatout

H.H.

(2010) C-flavonoidal glycosides from Erythrina caffra flowers. Natural. Product Science, 16, 217–222.

Chacha

, Bojase-Moleta

, Majinda

R.R.T.

(2005) Antimicrobial and radical scavenging flavonoids from the stem wood of Erythrina latissima. Phytochemistry, 66, 99–104.

El-Masry

, Amer

M.E.

, Abdel-Kader

M.S.

, Zaatout

H.H.

(2002) Prenylated flavonoids of Erythrina lysistemon grown in Egypt. Phytochemistry, 60, 783–787.

Wandji

, Awanchiri

S.S.

, Fomum

Z.T.

, Tillequin

, Michel-Daniwicz

(1995) Prenylated isoflavonoids from Erythrina senegalensis. Phytochemistry, 39, 677–681.

Yenesew

, Derese

, Irungu

, Midiwo

J.O.

, Waters

N.C.

, Liyala

, Akala

, Heydenreich

, Peter

M.G.

(2003) Flavonoids and isoflavonoids with antiplasmodial activities from the root bark of Erythrina abyssinica. Planta Medica, 69, 658–661.

Abdel-Kader

M.S.

, Amer

M.E.

, Tang

, Kingston

D.G.

(2006) Two new isoflavone derivatives from the roots of an Egyptian collection of Lotus polyphyllos. Natural Product Research, 20, 922–926.

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