The essential oil of Satureja cuneifolia Ten. was characterized by a high concentration of the phenolic compounds carvacrol (21.3%) and thymol (9.2%). The in vitro activity of the essential oil against Legionela pneumophila serogroups (SG) 1 and 2-15 and Legionella spp. from different sources, using micro-dilution, showed that L. pneumofila is sensitive to the oil, with MICs ranging from 0.12 to 0.5%, v/v, and a MBC at 0.5 to 1%, v/v. The essential oil of S. cuneifolia was effective in the reduction of Legionellosis infections.
ŠilićČ. (1979) Monography of genera Satureja L., Calamintha Miller, Micromeria Bentham, Acinos Miller and Clinopodium L. in flora of Yugoslavia [In Bosnian]. Zemaljski muzej BiH, Sarajevo
2.
BezićN, DunkićV, RadonićA. (2001) Glandular apparatus and essential oil constituents of Satureja cuneifolia Ten. Acta Biologica Cracoviensis. Series Botanica, 43, 65–68
3.
BezićN, ŠamanićI, DunkićV, BesendorferV, PuizinaJ. (2009) Essential oil composition and internal transcribed spacer (ITS) sequence variability of four South-Croatian Satureja species (Lamiaceae). Molecules, 14, 925–938
4.
SkočibušićM, BezićN, DunkićV. (2004) Variability of Satureja cuneifolia Ten. essential oils and antimicrobial activity depending on the stage of development. European Food Research and Technology, 218, 367–371.
5.
BezićN, SkočibušićM, DunkićV. (2005) Phytochemical composition and antimicrobial activity of Satureja montana L. and Satureja cuneifolia Ten. essential oils. Acta Botanica Croatica, 64, 313–322
6.
SkočibušićM, BezićN, DunkićV. (2006) Phytochemical composition and antimicrobial activities of the essential oils from Satureja subspicata Vis. growing in Croatia. Food Chemistry, 96, 20–28.
7.
MondelloF, GirolamoA, ScaturroM, RicciML. (2009) Determination of Legionella pneumophila susceptibility to Melaleuca alternifolia Cheel (tea tree) oil by an improved broth micro-dilution method under vapour controlled conditions. Journal of Microbiology Methods, 77, 243–248.
8.
ChangCW, ChangWL, ChangST, ChengSS. (2008) Antibacterial activities of plant essential oils against Legionella pneumophila. Water Research, 42, 278–286
9.
OkeF, AslimB, OzturkS, AltundagS. (2009) Essential oil composition, antimicrobial and antioxidant activities of Satureja cuneifolia Ten. Food Chemistry, 112, 874–879
10.
BaydarH, SagdicO, OzkanG, KaradoganT. (2004) Antibacterial activity and composition of essential oils from Origanum, Thymbra and Satureja species with commercial importance in Turkey. Food Control, 15, 169–172.
11.
LambertRJW, SkandamisPN, CootePJ, NychasGJE. (2001) A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. Journal of Applied Microbiology, 91, 453–462.
12.
KremerD, Vitali ČepoD, DunkićV, Dragojević MüllerI, KosalecI, BezićN, StabentheinerE. (2013) Phytochemical and Micromorphological Traits of Geranium dalmaticum and G. macrorrhizum (Geraniaceae). Natural Product Communications, 8, 645–650
13.
AdamsRP. (2007) Identification of essential oil components by gas chromatography/ mass spectroscopy. 4th. ed., Allured Publishing Corporation, Carol Stream IL, USA.