In the present study the chemical composition of the essential oils from aerial parts and flowers of Achillea ligustica All., collected in Lipari (Aeolian Islands) was evaluated by GC and GC-MS. (Z)-Chrysanthenyl acetate was the most abundant component of both oils (29.6% in A1 and 27.8% in F1), followed by viridiflorol (16.8% in A1 and 21.6% in F1), bornyl acetate (8.7% in A1 and 11.6% in F1) and 1,8-cineole (7.4% in A1 and 9.3% in F1). A comparison was made of the composition of the different populations studied so far. Futhermore, the free radical scavenging activity of the oil was determined by DPPH and ABTS methods.
ZagariA. (1996) In Medicinal plants. 4th ed., Vol. 3. Teheran University Publication, Teheran. 106–107; (b) Dodson C, Dummire WW. (2007) Mountain wildflowers of the Southern Rockies. University of New Mexico Press; (c) Honda G, Yelisada E, Tabata M, Sezik E, Fujita T, Takeda Y, Takaishi Y, Tanaka T. (1996) Traditional medicine in Turkey VI. Folk medicine in West Anatolia: Afyon, Kütahya, Denizli, Muĝla, Aydin provinces. Journal of Ethnopharmacology, 53, 75–87; (d) Ross J. (2003) In Combining western herbs and Chinese medicine: principles, practice, and material medica. Greenfields Press, Seattle. 165–181; (e) Saeidnia S, Gohari AR, Mokhber-Dezfuli N, Kuchi F. (2011) A review on phytochemistry and medicinal properties of the genus Achillea. DARU Journal of Pharmaceutical Science, 19, 173–186; (f) Konakchiev A, Todorova M, Mikhova B, Vitkova A, Najdenski H. (2011) Composition and antimicrobial activity of Achillea distans essential oil. Natural Product Communications, 6, 905–906; (g) Falconieri D, Piras A, Porcedda S, Marongiu B, Gonçalves MJ, Cabral C, Cavaleiro C, Salgueiro L. (2011) Chemical composition and biological activity of the volatile extracts of Achillea millefolium. Natural Product Communications, 6, 1527–1530; (h) Tabanca N, Demirci B, Gürbüz İ, Demirci F, Becnel JJ, Wedge DE, Başer KHC. (2011) Essential oil composition of five collections of Achillea biebersteinii from Central Turkey and their antifungal and insecticidal activity. Natural Product Communications, 6, 701–706.
3.
PignattiS. (1982) In Flora d'Italia.Edagricole, Bologna.
4.
BruniA., BalleroM., PoliF. (1997) Quantitative ethnopharmacological study of the Campidano Valley and Urzulei district, Sardinia, Italy. Journal of Ethnopharmacology, 57, 97–124; (b) Bader A, Panizzi L, Cioni PL, Flamini G. (2007) Achillea ligustica: composition and antimicrobial activity of essential oils from the leaves, flowers and some pure constituents. Central European Journal of Biology, 2, 206–212; (c) Atzei AD. (2003) In Le Piante nella Tradizione Popolare della Sardegna. Carlo Delfino Editor, Sassari, p. 66; (d) Simonpoli P. (1993) In Arburi, Arbe, Arbigliule, Savoirs Populaires sur les Plantes de Corse. Parc Naturel Régional de la Corse, Ajaccio; (e) Guarrera PM. (1999) Traditional anthelmintic, antiparasitic and repellent uses of plants in Central Italy. Journal of Ethnopharmacology, 68, 183–192.
5.
GrergerH., ZderoC., BohlmannF. (1984) Pyrrolidine and piperidine amides from Achillea. Phytochemistry, 23, 1503–1505; (b) Bruno M, Herz W. (1988) Guaianolides and other constituents of Achillea ligustica. Phytochemistry, 27, 1871–1872; (c) Tzakou O, Couladis M, Verykikodou E, Loukis A. (1995) Leaf flavonoids of Achillea ligustica and Achillea holosericea. Biochemical Systematics and Ecology, 23, 569–570; (d) Ahmed AA, Gati T, Hussein TA, Ali AT, Tzakou OA, Couladis MA, Mabry JT, Toth G. (2003) Ligustolide A and B, two novel sesquiterpenes with rare skeletons and three 1,10-seco-guaianolide derivatives from Achillea ligustica. Tetrahedron, 59, 3729–3735; (e) Boudjerda A, Zater H, Benayache S, Chalchat JC, Gonzalez-Platas J, Leon F, Brouard I, Bermejo J, Benayache F. (2008) A new guaianolide and other constituents from Achillea ligustica. Biochemical Systematics and Ecology, 36, 461–466; (f) Hegazy MF, Mohamed AEH, El-Sayed MA, Ohta S. (2008) A new chlorine-containing sesquiterpene lactone from Achillea ligustica. Zeitschrift für Naturforschung, 63b, 105–107; (g) Tuberoso CIG, Montoro P, Piacente S, Corona G, Deiana M, Dessì MA, Pizza C, Cabras P. (2009) Flavonoid characterization and antioxidant activity of hydroalcoholic extracts from Achillea ligustica All. Journal of Pharmaceutical and Biomedical Analysis, 50, 440–448; (h) Mahmoud AA, Al-Shihry SS, Hegazy MEF. (2012) A New epimeric sesquiterpene lactone from Achillea ligustica. Records of Natural Products, 6, 21–27.
6.
ConfortiF., LoizzoM.R., StattiG.A., MenichiniF. (2005) Comparative radical scavenging and antidiabetic activities of methanolic extract and fractions from Achillea ligustica All. Biological and Pharmaceutical Bulletin, 28, 1791–1794; (b) Tzakou O, Loukis A, Verykokidou E, Roussis V. (1995) Chemical constituents of the essential oil of Achillea ligustica All. from Greece. Journal of Essential Oil Research, 7, 549–550; (c) Maffei M, Germano F, Doglia G, Chialva F. (1993) Essential oils, chromosome numbers and karyotypes from Italian Achillea species. Part II. Journal of Essential Oil Research, 5, 61–70; (d) Tuberoso CIG, Kowalczyk A, Coroneo V, Russo MT, Dessi S, Cabras P. (2005) Chemical composition and antioxidant, antimicrobial, and antifungal activities of the essential oil of Achillea ligustica All. Journal of Agricultural and Food Chemistry, 53, 10148–10153; (e) Muselli A, Pau M, Desjobert JM, Foddai M, Usai M, Costa J. (2009)Volatile constituents of Achillea ligustica All. by HS-SPME/GC/GC-MS. comparison with essential oils obtained by hydrodistillation from Corsica and Sardinia. Chomatographia, 69, 575–585; (f) Filippi JJ, Lanfranchi DA, Prado S, Baldovini N, Meierhenrich UJ. (2006) Composition, enantiomeric distribution, and antibacterial activity of the essential oil of Achillea ligustica All. from Corsica. Journal of Agricultural and Food Chemistry, 54, 6308–6313; (g) Maggi F, Bramucci M, Cecchini C, Coman MM, Cresci A, Cristalli G, Lupidi G, Papa F, Quassinti L, Sagratini G, Vittori S. (2009) Composition and biological activity of essential oil of Achillea ligustica All. (Asteraceae) naturalized in Central Italy: ideal candidate for anti-cariogenic formulations. Fitoterapia, 80, 313–319; (h) Cecchini C, Silvi S, Cresci A, Piciotti A, Caprioli G, Papa F,. Sagratini G, Vittori S, Maggi F. (2012) Antimicrobial efficacy of Achillea ligustica All. (Asteraceae) essential oils against reference and isolated oral microorganisms. Chemistry & Biodiversity, 9, 12–24; (i) Radulović N, Zlatković B, Palić R, Stojanović G. (2007) Chemotaxonomic significance of the Balkan Achillea volatiles. Natural Product Communications, 2, 453–474.
7.
ConfortiF., MenichiniF., FormisanoC., RiganoD., SenatoreF., BrunoM., RosselliS., çelikS. (2012) Anthemis wiedemanniana essential oil prevents LPS-induced production of NO in RAW 264.7 macrophages and exerts antiproliferative and antibacterial activities in vitro. Natural Product Research, 26, 1594–1601; (b) Zito P, Sajeva M, Bruno M, Maggio A, Rosselli S, Formisano C, Senatore F. (2010) Essential oil composition of stems and fruits of Caralluma europaea N.E.Br. (Apocynaceae). Molecules, 15, 627–638.
8.
SacchettiG., MaiettiS., MuzzoliM., ScagliantiM., ManfrediniS., RadiceM., BruniR. (2005) Comparative evaluation of 11 essential oils of different origin as functional antioxidants, antiradicals and antimicrobials in foods. Food Chemistry, 91, 621–632; (b) Soares JR, Dins TCP, Cunha AP, Ameida LM. (1997) Antioxidant activity of some extracts of Thymus zygis. Free Radical Research, 26, 469–478; (c) Hanato T, Kagawa H, Yasuhara X, Okuda T. (1988) Two new flavonoids and other constituents in licorice root: their relative astringency and radical scavenging effect. Chemical & Pharmaceutical Bulletin, 36, 1090–1097; (d) Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. (1999) Antioxidant activity applying an improved ABTS radical decolorization assay. Free Radical Biology and Medicine, 26, 1231–1237.
