Berbanine: A New Isoquinoline-Isoquinolone Alkaloid from Berberis Vulgaris (Berberidaceae)

Abstract

A new isoquinoline-isoquinolone alkaloid was isolated from the root bark of Berberis vulgaris and named berbanine. The structure was established by spectroscopic methods (including 2D NMR, HR-EI-MS).

Keywords

Berberis vulgaris Berberidaceae Alkaloid Isoquinoline-isoquinolone dimer Berbanine

References

Phillipson

, Roberts

, Zenk

. (1985) The chemistry and biology of isoquinoline alkaloids. Springer-Verlag, Berlin, Germany, 126–128.

Hussain

, Siddiqui

, Shamma

(1989) Berbidine: a simple isoquinoline-isoquinolone dimer. Journal of Natural Products, 52, 317–319.