Ethanolic extracts of Salvia officinalis leaves demonstrated antibacterial activity against Bacillus cereus. Fractionation of the extracts led to the isolation of the most active antibacterial compound, which, from spectroscopic and LC-MS evidence, was proved to be the diterpene, methyl carnosate.
PearsonDA, FrankelEN, AeschbachR, GermanJB. (1997) Inhibition of endothelial cell-mediated oxidation of low-density lipoprotein by rosemary and plant phenolics. Journal of Agricultural and Food Chemistry, 45, 578–582.
2.
MiladinovićD, MiladinovićL. (2000) Antimicrobial activity of essential oil of sage from Serbia. Facta Universitatis, 2, 97–100.
MiuraK, KikuzakiH, NakataniN. (2001) Apianane terpenoids from Salvia officinalis. Phytochemistry, 58, 1171–1175.
5.
RustaiyanA, MasoudiS, Tabatabaei-AnarakiM. (2007) Terpenoids from Iranian Salvia species. Natural Product Communications, 2, 1031–1042.
6.
MurkoD, RamicS, KekicM. (1974) Tannins of Salvia officinalis and their change during storage. Planta Medica, 25, 295–300.
7.
WangM, KikuzakiH, ZhuN, SangS, NakataniN, HoCT. (2000) Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis). Journal of Agricultural and Food Chemistry, 48, 235–238.
8.
CuvelierME, RichardH, BersetC. (1996) Antioxidative activity and phenolic composition of pilot-plant and commercial extracts of sage and rosemary. Journal of the American Oil Chemists’ Society, 73, 645–652.
9.
LuY, FooLY. (2000) Flavonoid and phenolic glycosides from Salvia officinalis. Phytochemistry, 55, 263–267.
10.
LuY, FooLY, WongH. (1999) Sagecoumarin, a novel caffeic acid trimer from Salvia officinalis. Phytochemistry, 52, 1149–1152.
11.
TadaM, OkunoK, ChibaK, OhnishiE, YoshiiT. (1994) Antiviral diterpenes from Salvia officinalis. Phytochemistry, 35, 539–541.
12.
BrieskornCH, KapadiaZ. (1980) Constituents of Salvia officinalis. XXIV: Triterpenes and pristan in leaves of Salvia officinalis. Planta Medica, 38, 86–89.
13.
CherevatyiVS, VashenkoTN, ShishkovGZ. (1980) Comparative evaluation of the antibacterial action of different extracts from Salvia officinalis. Rastitel'nye Resursy, 16, 137–139
14.
Anonymus. (1994) Salviae folium (Salbeiblaetter), Bundesanzeiger Nr. 90/1985, Bundesanzeiger Nr. 50/1990. In Verffentliche Monographien. Bekanntmachung her die Zulassung und Registrierung von Arzneimitteln. Entwurf der Aufberetung-kommission fr den humanmedi zinischen Bereich, phytotherapeutische Therapie-richtung und Stoffgruppe (Kommission E), Bundesinstitut fr Arzneimittel und Medizinprodukte Berlin, pp. 464
15.
FaragRS, SalemFL, BadeiAZMA, HassaneinDE. (1986) Biochemical studies on the essential oil of some medicinal plants. Fette Seifen Anstrichmittel, 88, 69–72.
16.
JanicsákG, ZupkóI, MáthéI, HohmannJ. (2010) Comparative study of the antioxidant activities of eleven Salvia species. Natural Product Communications, 5, 227–230
17.
SchwartzK, TernesW. (1992) Antioxidative constituents of Rosmarinus officinalis and Salvia officinalis. II Isolation of carnosic acid and formation of other phenolic diterpenes. Zeitschrift für Lebensmittel Untersuchung und Forschung, 195, 99–103.
18.
CuvelierME, BersetC, RichardH. (1994) Antioxidant constituents in sage (Salvia officinalis). Journal of Agricultural and Food Chemistry, 42, 665–669
19.
KoşarM, DormanHJD, BaşerKHC, HiltunenR. (2010) Salvia officinalis L.: Composition and antioxidant-related activities of a crude extract and selected sub-fractions. Natural Product Communications, 5, 1453–1456.
20.
MamadalievaNZ, EgamberdievaD, ClimatiE, TriggianiD, CeccarelliD, SultanovSA, NigmatullaevOM, AzimovaShS, TiezziA. (2009) The cytotoxic activities of four Salvia species native from Uzbekistan. Uzbek Biology Journal, 3–7.
21.
BernadesWA, LucariniL, TozattiMG, SouzaMG, SilvaML, FilhoAA, MartinsCH, CrottiAE, PaulettiPM, GroppoM, CunhaWR. (2010) Antimicrobial activity of Rosmarinus officinalis against oral pathogens: relevance of carnosic acid and carnosol. Chemistry & Biodiversity, 7, 1835–1840.
22.
TadaM, OhkandaT, KurabeJ. (2010) Synthesis of carnosic acid and carnosol, anti-oxidants in rosemary, from pisiferic acid, the major constituent of Sawara. Chemical & Pharmaceutical Bulletin, 58, 27–29.
23.
DuraipandiyanV, AyyanarM, IgnacimuthuS. (2006) Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India. BMC Complementary and Alternative Medicine, 6(35), 1–7.
