Two new secoiridoid glycosides, named ethyl secologanoside (1) and 6′-O-α-L-arabinopyranosyl demethylsecologanol (2), together with three known ones, secologanoside (3), secoxyloganin (4), and loniceroside (5), were isolated from the dried buds of Lonicera macranthoides. The structures of the new compounds were determined on the basis of detailed spectroscopic analyses and acidic hydrolysis.
ChenM, WuW, ShenG., LuoS, LiH. (1994) Chemical constituents of Lonicera macranthoides Hand.-Mazz part V. Isolation and structures of macranthoin F and G. Yaoxue Xuebao, 29, 617–620
2.
MaoQ, CaoD, JiaX. (1993) Studies on the chemical constituents of Lonicera macranthoides Hand.-Mazz. Yao Xue Xue Bao, 28, 273–281
3.
ShiJ, ChenX, WanL. (1999) Hepatoprotective effects of some constituents of Lonicera fulvotomentosa Hsu et S.C. Cheng, and L. macranthoides Hand.-Mazz. against carbon tetrachloride- and D-galactosamine-induced liver injuries in mice and rats. Zhongguo Zhongyao Zazhi, 24, 363–364
4.
WangJ, ZhaoX, QiQ, TaoL, ZhaoQ. (2009) Macranthoside B, a hederagenin saponin extracted from Lonicera macranthoides and its anti-tumor activities in vitro and in vivo. Food and Chemical Toxicology, 47, 1716–1721.
5.
ChenC, QiL, LiH, LiP, YiL, MaH. (2007) Simultaneous determination of iridoids, phenolic acids, flavonoids, and saponins in Flos Lonicerae and Flos Lonicerae Japonicae by HPLC-DAD-ELSD coupled with principal component analysis. Journal of Separation Science, 30, 3181–3192
6.
ChenY, ZhaoY, WangM, SunH, DongY, FengX. (2012) The first chlorogenic acid ester saponin from Lonicera macranthoides. Chemistry of Natural Compounds, 47, 940–943
7.
ChenY, ShanY, ZhaoY, WangQ, WangM, FengX, LiangJ. (2012) Two new triterpenoid saponins from Lonicera macranthoides. Chinese Chemical Letters, 23, 325–328
8.
ChenY, FengX, WangM, JiaX, ZhaoY, DongY. (2009) Triterpene glycosides from Lonicera. II. Isolation and structural determination of glycosides from flower buds of Lonicera macranthoides. Chemistry of Natural Compounds, 45, 514–518
9.
ChenM, LuoS, LiH. (1990) Chemical constituents of Lonicera macranthoides Hand.-Mazz. I. Structure of macranthoiside I. Chinese Chemical Letters, 1, 219–220
10.
ChaiX, LiS, LiP. (2005) Quality evaluation of Flos Lonicerae through a simultaneous determination of seven saponins by HPLC with ELSD. Journal of Chromatography A, 1070, 43–48.
EinaggarLJ, BealJL. (1980) Iridoids. A review. Journal of Natural Products, 43, 649–707
13.
KitajimaM, FujiiN, YoshinoF, SudoH, SaitoK, AimiN, TakayamaH. (2005) Camptothecins and two new monoterpene glucosides from Ophiorrhiza liukiuensis. Chemical and Pharmaceutical Bulletin, 53, 1355–1358.