Pistacides A and B (1–2), two new flavonoid glycosides, have been isolated from the methanolic extract of the aerial parts of Pistacia integerrima, along with 2′-hydroxyisoorientin (3), echioidinin 2′-O-β-D-(6″-O-acetyl) glucopyranoside (4), chrysoeriol (5), and diandraflavone A (6), reported for the first time from this species. Their structures were elucidated by spectroscopic analysis including 2D NMR, FAB-MS, and acidic hydrolysis.
NasirE., AliS.I. (1983) Anacardiaceae. Flora of Pakistan, NasirY.J. (Ed.). Nazir Print Works, Karachi, No. 152. 11.
2.
ChopraR.N., ChopraI.C., HandaK.L., KapoorL.D. (1982) Indigenous Drugs of India, 2nd ed. Academic Publishers, Delhi. 377–379.
3.
(a) ChopraR.N., BadhwarR.K., GhoshS. (1965) Poisonous Plants of India.Indian Council of Agricultural Research, New Delhi. 270; (b) Pant S, Samant SS. (2010) Ethnobotanical observations in the Mornaula Reserve Forest of Kumoun, West Himalaya, India. Ethnobotanical Leaflets, 14, 193–217.
4.
AnsariS.H., AliM. (1996) Analgesic and anti-inflammatory activity of tetracyclic triterpenoids isolated from Pistacia integerrima galls. Fitoterapia, 67, 103–105.
5.
AhmadN.S., WaheedA., FarmanM., QayyumA. (2010) Analgesic and anti-inflammatory effects of Pistacia integerrima extracts in mice. Journal of Ethnopharmacology, 129, 250–253.
6.
AhmadN.S., FarmanM., NajmiM.H., MianK.B., HassanA. (2008) Pharmacological basis for use of Pistacia integerrima leaves in hyperuricemia and gout. Journal of Ethnopharmacology, 117, 478–482.
7.
(a) AnsariS.H., AliM., QadryJ.S. (1993) Three new tetracyclic triterpenoids from galls of Pistacia integerrima Stew. Pharmazie, 48, 215–217;(b) Ansari SH, Ali M, Qadry JS. (1994) New tetracyclic triterpenoids from Pistacia integerrima galls. Pharmazie, 49, 356–357; (c) Farman M. (2005) Contribution to the study of flavonoids from two species of Pistacia (Anacardiaceae). A Doctoral Thesis, Quaid-i-Azam University, Islamabad, Pakistan.
8.
AhmadS., AliM., AnsariS.H. (2011) Phenolic constituents from the galls of Pistacia integerrima Stewart. Indian Journal of Chemistry, 50B, 115–118.
9.
UddinG., RaufA., IrfanM., Waliullah, KhanI., AliM., TaimurM., Ur-RehmanI., Samiullah. (2011) Phytochemical screening of Pistacia chinensis var. integerrima. Middle-East Journal of Scientific Research, 7, 707–711.
10.
AhmadS., AliM., AnsariS.H., AhmedF. (2010) Phytoconstituents from the galls of Pistacia integerrima Stewart. Journal of Saudi Chemical Society, 14, 409–412.
11.
MabryT.J., MarkhamK.R., ThomasM.B. (1970) The Systematic Identification of Flavonoids.Springer-Verlag, New York, 81 and 211.
12.
(a) MarkhamK.R., WollenweberE., SchillingG. (1987) Structure revision for two C-methylflavanones from Pityrogramma-Pallida. Journal of Plant Physiology, 131, 45–48;(b) Maltese F, Erkelens C, Kooy FVD, Choi YH, Verpoorte R. (2009) Identification of natural epimeric flavanone glycosides by NMR spectroscopy. Food Chemistry, 116, 575–579.
13.
AgrawalP.K. (1989) Carbon-13 NMR of Flavanoids, Elsevier, Amsterdam, 41–182.
14.
(a) MongkolsukS., DeanF.M. (1964) Pinostrobin and alpinetin from Kaempferia pandurata. Journal of the Chemical Society, 4654–4655; (b) Batterham TJ, Highet RJ. (1964) Nuclear magnetic spectra of flavonoids. Australian Journal of Chemistry, 17, 428–439.
KomatsuM., YokoeI., ShiratakiY. (1978) Studies on the constituents of Sophora spp. Part 13. Constituents of the aerial parts of Sophora tomentosa part 2. Chemical and Pharmaceutical Bulletin, 26, 3863–3870.
17.
Narian-NandK. (1977) Flavonoids from Vernonia fasciculate Michx. Isolation of genkwanin and a new flavone disaccharide, fasciculation. Journal of the Chemical Society, Perkin Transactions 1, 1018–1020.
18.
NorbaekR., BrandtK., KondoT. (2000) Identification of flavone C-glycosides including a new flavonoid chromophore from barley leaves (Hordeum vulgare L.) by improved NMR techniques. Journal of Agricultural and Food Chemistry, 48, 1703–1707.
19.
ReddyM.V.B., KishoreP.H., RaoC.V., GunasekarD., CauxC., BodoB. (2003) New 2′-oxygenated flavonoids from Andrographis affinis. Journal of Natural Products, 66, 295–297.
HsiehP.W., ChangF.R., LeeK.H., HwangT.L., ChangS.M., WuY.C.A. (2004) New anti-HIV alkaloid, drymaritin, and a new C-glycoside flavonoid, diandraflavone, from Drymaria diandra. Journal of Natural Products, 67, 1175–1177.
