The chemical constituents of the roots of two Ligularia lankongensis samples collected in Yunnan and Sichuan Provinces, China, were investigated, together with the DNA sequence of the atpB-rbcL and ITS regions. Four new highly oxygenated bisabolane-type sesquiterpenes (1 – 4) were obtained. Intraspecific diversity in the DNA sequence was found to be limited.
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2.
NaganoH, HanaiR, YamadaH, MatsushimaM, MiuraY, HoyaT, OzawaM, FujiwaraM, KodamaH, TorihataA, OnukiH, NezuY, KawaiS, YamazakiM, HirotaH, SaitoY, ToriM, OhsakiA, GongX, KurodaC. (2011) Chemical and genetic study of Ligularia duciformis and related species in Sichuan and Yunnan Provinces of China, Chemistry and Biodiversity, in press (DOI: 10.1002/cbdv.201100240); and references cited therein.
3.
NaganoH, MatsushimaM, YamadaH, HanaiR, GongX, KurodaC. (2010) Two new furanoeremophilane sesquiterpenoids from Ligularia oligonema. Natural Product Communications, 5, 1–4.
4.
SaitoY, HattoriM, IwamotoY, TakashimaY, MiharaK, SasakiY, FujiwaraM, SakaokuM, ShimizuA, ChaoX, KurodaC, GongX, HanaiR, ToriM. (2011) Overlapping chemical and genetic diversity in Ligularia lamarum and Ligularia subspicata. Isolation of ten new eremophilanes and a new seco-bakkane compound. Tetrahedron, 67, 2220–2231; and references cited therein.
5.
NaganoH, KandaM, YamadaH, HanaiR, GongX, KurodaC. (2010) Chemical and genetic study of Ligularia anoleuca and L. veitchiana in Yunnan and Sichuan Provinces of China. Helvetica Chimica Acta, 93, 1945–1952; and references cited therein.
6.
TorihataA, ChaoX, KurodaC, HanaiR, HirotaH, GongX. (2009) Chemical and genetic differentiation of Ligularia hodgsonii in Japan and China, Chemistry and Biodiversity, 6, 2184–2191.
7.
NaganoH, TorihataA, MatsushimaM, HanaiR, SaitoY, BabaM, TanioM, OkamotoY, TakashimaY, IchiharaM, GongX, KurodaC, ToriM. (2009) Chemical and genetic study of Ligularia cyathiceps in Yunnan Province of China. Helvetica Chimica Acta, 92, 2071–2081.
8.
ToriM, TanioY, OkamotoY, SaitoY, GongX, KurodaC, HanaiR. (2008) Chemical constituents of Ligularia franchetiana collected in Yunnan Province of China. Heterocycles, 75, 2029–2034.
9.
KurodaC, HanaiR, NaganoH, ToriM, GongX. (2012) Diversity of furanoeremophilanes in major Ligularia species in the Hengduan Mountains. Natural Product Communications, 7, 7, 539–548.
10.
TanAM, HeHP, ZhangM, WangZT, HaoXJ. (2007) Two new sesquiterpenes from Ligularia lankongensis. Helvetica Chimica Acta, 90, 101–104; and references cited therein.
11.
WangQ, ChenT-H, BastowKF, LeeK-H, ChenD-F. (2010) AltaicalarinsA-D, cytotoxic bisabolane sesquiterpenes from Ligularia altaica. Journal of Natural Products, 73, 139–142.
12.
BabaH, YaoitaY, KikuchiM. (2007) Sesquiterpenoids and lactone derivatives from Ligularia dentata. Helvetica Chimica Acta, 90, 1028–1037;
HanaiR, GongX, ToriM, KondoS, OtoseK, OkamotoY, NishihamaT, MurotaA, ShenY, WuS, KurodaC. (2005) Chemical and genetic study of Ligularia tongolensis, Ligularia cymbulifera, and Ligularia atroviolacea in the Hengduan Mountains of China. Bulletin of Chemical Society of Japan, 78, 1302–1308.
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TamuraK, PetersonD, PetersonN, StecherG, NeiM, KumarS. (2011) MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Molecular Biology and Evolution, 28, 2731–2739.
