The essential oil of an Argentine collection of the annual herb Acanthospermum hispidum DC. (Asteraceae), which contains the sesquiterpenoids β-caryophyllene (35.2%), α-bisabolol (11.4%), and germacrene D (11.1%) as major constituents, displayed molluscicidal effects on an adult population of Biomphalaria peregrina Orbigny (LD50 37.8 μg/mL) and produced alteration of the feeding and oviposition behavior of the polyphagous insect Spodoptera frugiperda Smith when incorporated in the larval diet at 250 μg/g. In addition, a selective antibacterial activity was observed against pathogenic strains of Staphylococcus aureus and Enterococcus faecalis (MICs 62.5 and 125 μg/mL), but was inactive at 125 μg/mL against three beneficial lactic acid bacteria. Synergistic interactions were further validated by FIC index determination of the combination of the antibiotics oxacillin and gentamicin and the essential oil on the four pathogenic strains evaluated.
AraújoEL, RandauKP, Sena-FilhoJG, Mendonça PimentelRM, XavierHS. (2008) Acanthospermum hispidum DC. (Asteraceae): perspectives for a phytotherapeutic product. Brazilian Journal of Pharmacognosy, 18, 777–784.
2.
AdjanohounEJ, AdjakidjeV, AhyiMRA, Aké assiL, AkoegninouA, d'AlmeidaJ, ApovoF, BoukefK, ChadareM, CussetG, DramaneK, EyméJ, GassitaJN, GbaguidiN, GoudotéE, GuinkoP, HoungnonP, LoI, KeitaA, KiniffoHV, Kone-BambaD, Musampa NseyyaA, SaadouM, SodogandjiTh, de SouzaS, TchabiA, Zinsou DossaC, ZohounTh. (1989) Contribution aux études ethnobotaniques et floristiques en République Populaire du Bénin. In Médecine traditionnelle et pharmacopée. Agence de Coopération culturelle et technique, Cotonou, 55, 63, 97, 113, 143, 163, 205, 295, 319, 339.
3.
AdjanohounEJ, AhyiMRA, Aké assiL, BaniakinaJ, ChibonP, CussetG, DoulouV, EnzanzaA, EyméJ, GoudotéE, KeitaA, MbembaC, MolletJ, MoutsambotéJM, MpatiJ, SitaP. (1988) Contribution aux études ethnobotaniques et floristiques en République Populaire du Congo. In Médecine traditionnelle et pharmacopée. Agence de Coopération culturelle et technique, Brazzaville, 69, 101, 109.
4.
KerharoJ, AdamJG. (1974) La pharmacopée sénégalaise traditionnelle. In Plantes médicinales et toxiques, Vigot frères, Paris, 202, 221, 250, 289, 512.
5.
ToursarkissianM. (1980) Plantas medicinales de la Argentina. Sus nombres botánicos, vulgares. Usos y distribución geográfica. Hemisferio SurS.A. (Ed.), Buenos Aires, Argentina, 25–42.
6.
Martinez CrovettoR. (1981) Las plantas utilizadas en medicina en el noroeste de Corrientes. Miscelánea, 69, 106–117.
7.
BeroJ, GanfonH, JonvilleMC, FrédérichM, GbaguidiF, DeMolP, MoudachirouM, Quetin-LeclercqJ. (2009) In vitro antiplasmodial activity of plants used in Benin in traditional medicine to treat malaria. Journal of Ethnopharmacology, 122, 439–444.
8.
KrausW, Koll-WeberM, MaileR, WunderT, VoglerB. (1994) Biologically active constituents of tropical and subtropical plants. Pure and Applied Chemistry, 66, 2347–2352.
9.
FleischerTC, AmeadeEPK, SawerIK. (2003) Antimicrobial activity of the leaves and flowering tops of Acanthospermum hispidum. Fitoterapia, 74, 130–132.
10.
SummerfieldA, KeilGM, MettenleiterTC, RzihaHJ, SaalmullerA. (1997) Antiviral activity of an extract from leaves of the tropical plant Acanthospermum hispidum. Antiviral Research, 36, 55–62.
11.
MothanaRA, LindequistU, GruenertR, BednarskiPJ. (2009) Studies of the in vitro anticancer, antimicrobial and antioxidant potentials of selected Yemeni medicinal plants from the island Soqotra. BMC Complementary and Alternative Medicine, 9, 7–17.
12.
LemonicaIP, AlvarengaCMD. (1994) Abortive and teratogenic effect of Acanthospermum hispidum DC and Cajanus cajan (L) Millps in pregnant rats. Journal of Ethnopharmacology, 43, 39–44.
13.
MenutC, MolanguiT, LamatyG, OuambaJM, SilouT, BessièreJM. (1995) Aromatic plants of Tropical Central Africa. XXIV Volatile constituents of Acanthospermum hispidum DC. from the Congo. Journal of Essential Oil Research, 7, 589–592.
14.
JainSR, KarA. (1971) The antibacterial activity of some essential oils and their combinations. Planta Medica, 20, 118–123.
15.
JainSR, JainMR. (1972) Antifungal studies on some indigenous volatile oils and their combinations. Planta Medica, 22, 136–139.
16.
AdamsRP. (2007) Identification of essential oil components by gas chromatography / mass spectroscopy. 4th Ed. Allured Publishing Corporation, Carol Stream, Illinois, USA.
17.
Regnault-RogerC. (1997) The potential of botanical essential oils for insect pest control. Integrated Pest Management Reviews, 2, 25–34.
18.
WHO. (1965) Bulletin of the World Health Organization, 33, 567–581.
19.
GiovanelliA, SilvaCL, MedeirosL, VasconcellosMC. (2002) The molluscicidal activity of niclosamide (Bayluscide WP70®) on Melanoides tuberculata (Thiaridae), a snail associated with habitats of Biomphalaria glabrata (Planorbidae). Memórias do Instituto Oswaldo Cruz, 97, 743–745.
20.
El-KamaliHH, El-NourRO, KhalidSA. (2010) Molluscicidal activity of the essential oils of Cymbopogon nervatus leaves and Boswellia papyrifera resins. Current Research Journal of Biological Sciences, 2, 139–142.
21.
BurtS. (2004) Essential oils: their antibacterial properties and potential applications in foods- a review. International Journal of Food Microbiology, 94, 223–253.
22.
MaggiF, BramucciM, CecchiniC, ComanMM, CresciA, CristalliG, LupidiG, PapaF, QuassintiL, SagratiniG, VittoriS. (2009) Composition and biological activity of essential oil of Achillea ligustica All. (Asteraceae) naturalized in central Italy: Ideal candidate for anti-cariogenic formulations. Fitoterapia, 80, 313–319.
23.
LacroixM, OussalahM, CailletS. (2006) Mechanism of action of Spanish oregano, Chinese cinnamon, and savory essential oils against cell membranes and walls of Escherichia coli O157:H7 and Listeria monocytogenes. Journal of Food Protection, 69, 1046–1055.
24.
PetersenPJ, LabthavikulP, JonesCH, BradfordPA. (2006) In vitro antibacterial activities of tigecycline in combination with other antimicrobial agents determined by chequeboard and time-kill kinetic analysis. Journal Antimicrobial Chemotherapy, 57, 573–576.
25.
Van VuurenSF, ViljoenAM. (2009) Interaction between the non-volatile and volatile fractions on the antimicrobial activity of Tarchonanthus camphoratus. South African Journal of Botany, 75, 505–509.
26.
ColeMD. (1994) Key antifungal, antibacterial and anti-insect assay a critical review. Biochemical Systematics and Ecology, 22, 837–856.
27.
CarpinellaMC, DefagoMT, ValladaresG, PalaciosSM. (2003) Antifeedant and insecticidal properties of a limonoid from Melia azedarach (Meliaceae) with potential use for pest management. Journal of Agricultural and Food Chemistry, 51, 369–374.
28.
Kasten JúniorP, PrecetiACM, ParraJRP. (1978) Dados biológicos comparativos de Spodoptera frugiperda (J.E. Smith, 1797) em duas dietas artificiais e substrato natural. Revista de Agricultura, 53, 68–78.
29.
MarchantYY, BalzaF, AbeysekeraBF, TowersGHN. (1984) Molluscicidal activity of sesquiterpene lactones. Biochemical Systematics and Ecology, 12, 285–286.
CartagenaE, MontanaroS, BardónA. (2008) Improvement of the antibacterial activity of sesquiterpene lactones. Revista Latinoamericana de Química, 36, 43–51.
